Reactome | col5a3b [endoplasmic reticulum lumen]

col5a3b [endoplasmic reticulum lumen]

Stable Identifier

R-DRE-2023574

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

endoplasmic reticulum lumen

Synonyms

3x4Hyp-3Hyp-GalHyl-COL4A4, A0A0R4IN07

Locations in the PathwayBrowser

Expand all

Extracellular matrix organization (Danio rerio)

- Collagen formation (Danio rerio)
  - Collagen biosynthesis and modifying enzymes (Danio rerio)
    - COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates (Danio rerio)
      - COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides [endoplasmic reticulum lumen] (Danio rerio)
        
        Galactosyl-hydroxylysyl collagen propeptides [endoplasmic reticulum lumen] (Danio rerio)
        
        3,4-Hyp 5-Gal-Hyl collagen propeptides [endoplasmic reticulum lumen] (Danio rerio)
        
        col5a3b [endoplasmic reticulum lumen] (Danio rerio)
      - Galactosyl-hydroxylysyl collagen propeptides [endoplasmic reticulum lumen] (Danio rerio)
        
        3,4-Hyp 5-Gal-Hyl collagen propeptides [endoplasmic reticulum lumen] (Danio rerio)
        
        col5a3b [endoplasmic reticulum lumen] (Danio rerio)
    - Galactosylation of collagen propeptide hydroxylysines by PLOD3 (Danio rerio)
      - PLOD3:Fe2+ dimer:Galactosyl-hydroxylysyl collagen propeptides [endoplasmic reticulum membrane] (Danio rerio)
        
        Galactosyl-hydroxylysyl collagen propeptides [endoplasmic reticulum lumen] (Danio rerio)
        
        3,4-Hyp 5-Gal-Hyl collagen propeptides [endoplasmic reticulum lumen] (Danio rerio)
        
        col5a3b [endoplasmic reticulum lumen] (Danio rerio)
    - Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2. (Danio rerio)
      - COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides [endoplasmic reticulum lumen] (Danio rerio)
        
        Galactosyl-hydroxylysyl collagen propeptides [endoplasmic reticulum lumen] (Danio rerio)
        
        3,4-Hyp 5-Gal-Hyl collagen propeptides [endoplasmic reticulum lumen] (Danio rerio)
        
        col5a3b [endoplasmic reticulum lumen] (Danio rerio)
    - Glucosylation of collagen propeptide hydroxylysines (Danio rerio)
      - PLOD3:Fe2+ dimer:Galactosyl-hydroxylysyl collagen propeptides [endoplasmic reticulum membrane] (Danio rerio)
        
        Galactosyl-hydroxylysyl collagen propeptides [endoplasmic reticulum lumen] (Danio rerio)
        
        3,4-Hyp 5-Gal-Hyl collagen propeptides [endoplasmic reticulum lumen] (Danio rerio)
        
        col5a3b [endoplasmic reticulum lumen] (Danio rerio)
    - PLOD3:Fe2+ dimer:Galactosyl-hydroxylysyl collagen propeptides dissociates (Danio rerio)
      - Galactosyl-hydroxylysyl collagen propeptides [endoplasmic reticulum lumen] (Danio rerio)
        
        3,4-Hyp 5-Gal-Hyl collagen propeptides [endoplasmic reticulum lumen] (Danio rerio)
        
        col5a3b [endoplasmic reticulum lumen] (Danio rerio)
      - PLOD3:Fe2+ dimer:Galactosyl-hydroxylysyl collagen propeptides [endoplasmic reticulum membrane] (Danio rerio)
        
        Galactosyl-hydroxylysyl collagen propeptides [endoplasmic reticulum lumen] (Danio rerio)
        
        3,4-Hyp 5-Gal-Hyl collagen propeptides [endoplasmic reticulum lumen] (Danio rerio)
        
        col5a3b [endoplasmic reticulum lumen] (Danio rerio)
    - Procollagen triple helix formation (Danio rerio)
      - Collagen and procollagen triple helices:Serpin H1 [endoplasmic reticulum lumen] (Danio rerio)
        
        Collagen and procollagen triple helices [endoplasmic reticulum lumen] (Danio rerio)
        
        Non-fibrillar collagens [endoplasmic reticulum lumen] (Danio rerio)
        
        C-linked procollagen type IV trimers [endoplasmic reticulum lumen] (Danio rerio)
        
        C-linked procollagen alpha-3(IV), alpha-4(IV) alpha-5(IV) trimer [endoplasmic reticulum lumen] (Danio rerio)
        
        col5a3b [endoplasmic reticulum lumen] (Danio rerio)
      - Procollagen C-linked trimers [endoplasmic reticulum lumen] (Danio rerio)
        
        C-linked procollagen type IV trimers [endoplasmic reticulum lumen] (Danio rerio)
        
        C-linked procollagen alpha-3(IV), alpha-4(IV) alpha-5(IV) trimer [endoplasmic reticulum lumen] (Danio rerio)
        
        col5a3b [endoplasmic reticulum lumen] (Danio rerio)
    - Secretion of collagens (Danio rerio)
      - Collagens and tropocollagens:Serpin H1 [endoplasmic reticulum lumen] (Danio rerio)
        
        Collagens and tropocollagens [endoplasmic reticulum lumen] (Danio rerio)
        
        Non-fibrillar collagens [endoplasmic reticulum lumen] (Danio rerio)
        
        C-linked procollagen type IV trimers [endoplasmic reticulum lumen] (Danio rerio)
        
        C-linked procollagen alpha-3(IV), alpha-4(IV) alpha-5(IV) trimer [endoplasmic reticulum lumen] (Danio rerio)
        
        col5a3b [endoplasmic reticulum lumen] (Danio rerio)

External Reference Information

External Reference

UniProt:A0A0R4IN07

Gene Names

col5a3b

Reference Genes

ENSEMBL:ENSDARG00000101816

Other Identifiers

100463515

12959802

A_15_P308456

A_15_P549992

CUST_28466_PI428451953

CUST_28470_PI428451953

CUST_8835_PI428451958

DRER01711

DRER50125

ENSDART00000097946

ENSDART00000097946_2

GO:0003674

GO:0005198

GO:0005201

GO:0005575

GO:0005576

GO:0005594

GO:0005604

GO:0005615

GO:0008150

GO:0030198

GO:0030312

GO:0031012

GO:0032991

GT_Spec_NM_001190758.1_156396

XM_688785

Participates

as a candidate of

3,4-Hyp 5-Gal-Hyl collagen propeptides [endoplasmic reticulum lumen] (Danio rerio)

as a component of

C-linked procollagen alpha-3(IV), alpha-4(IV) alpha-5(IV) trimer [endoplasmic reticulum lumen] (Danio rerio)

Other forms of this molecule

col5a3b [endoplasmic reticulum lumen]

col5a3b [extracellular region]

Inferred From

Alpha-4(IV) chains [endoplasmic reticulum lumen] (Homo sapiens)

3x4Hyp-3Hyp-GalHyl-COL4A4 [endoplasmic reticulum lumen] (Homo sapiens)

Modified Residues

Name

(2S,4R)-4-hydroxyproline at unknown position

PsiMod Name

(2S,4R)-4-hydroxyproline

PsiMod Definition

A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline

Name

(2S,4R)-4-hydroxyproline at unknown position

PsiMod Name

(2S,4R)-4-hydroxyproline

PsiMod Definition

A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline

Name

(2S,4R)-4-hydroxyproline at unknown position

PsiMod Name

(2S,4R)-4-hydroxyproline

PsiMod Definition

A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline

Name

(2S,3S)-3-hydroxyproline at unknown position

PsiMod Name

(2S,3S)-3-hydroxyproline

PsiMod Definition

A protein modification that effectively converts an L-proline residue to 3-hydroxy-L-proline.

Name

O5-galactosyl-L-hydroxylysine at unknown position

PsiMod Name

O5-galactosyl-L-hydroxylysine

PsiMod Definition

A protein modification that effectively converts an L-lysine residue to O5-galactosyl-L-hydroxylysine.

Cross References

Ensembl

ENSDART00000158011, ENSDARP00000136818, ENSDARG00000101816