Reactome | col5a2a [endoplasmic reticulum lumen]

col5a2a [endoplasmic reticulum lumen]

Stable Identifier

R-DRE-2172925-2

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

endoplasmic reticulum lumen

Synonyms

3x4Hyp-COL16A1, F1QT86

Locations in the PathwayBrowser

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Extracellular matrix organization (Danio rerio)

- Collagen formation (Danio rerio)
  - Collagen biosynthesis and modifying enzymes (Danio rerio)
    - Collagen chain trimerization (Danio rerio)
      - Association of procollagen type XVI (Danio rerio)
        
        Alpha-1(XVI) chains [endoplasmic reticulum lumen] (Danio rerio)
        
        Homologues of 3x4Hyp-COL16A1 [endoplasmic reticulum lumen] (Danio rerio)
        
        col5a2a [endoplasmic reticulum lumen] (Danio rerio)
        
        C-linked procollagen type XVI trimer [endoplasmic reticulum lumen] (Danio rerio)
        
        Alpha-1(XVI) chains [endoplasmic reticulum lumen] (Danio rerio)
        
        Homologues of 3x4Hyp-COL16A1 [endoplasmic reticulum lumen] (Danio rerio)
        
        col5a2a [endoplasmic reticulum lumen] (Danio rerio)
    - Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen (Danio rerio)
      - Prolyl 3-hydroxylases:Fe2+:4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Danio rerio)
        
        4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Danio rerio)
        
        Homologues of 3x4Hyp-COL16A1 [endoplasmic reticulum lumen] (Danio rerio)
        
        col5a2a [endoplasmic reticulum lumen] (Danio rerio)
    - P3HB binds 4-Hyp-collagen propeptides (Danio rerio)
      - 4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Danio rerio)
        
        Homologues of 3x4Hyp-COL16A1 [endoplasmic reticulum lumen] (Danio rerio)
        
        col5a2a [endoplasmic reticulum lumen] (Danio rerio)
      - Prolyl 3-hydroxylases:Fe2+:4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Danio rerio)
        
        4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Danio rerio)
        
        Homologues of 3x4Hyp-COL16A1 [endoplasmic reticulum lumen] (Danio rerio)
        
        col5a2a [endoplasmic reticulum lumen] (Danio rerio)
    - P4HB:4-Hyp collagen propeptides dissociates (Danio rerio)
      - 4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Danio rerio)
        
        Homologues of 3x4Hyp-COL16A1 [endoplasmic reticulum lumen] (Danio rerio)
        
        col5a2a [endoplasmic reticulum lumen] (Danio rerio)
      - 4-Hyp collagen propeptides:P4HB [endoplasmic reticulum lumen] (Danio rerio)
        
        4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Danio rerio)
        
        Homologues of 3x4Hyp-COL16A1 [endoplasmic reticulum lumen] (Danio rerio)
        
        col5a2a [endoplasmic reticulum lumen] (Danio rerio)
    - Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines (Danio rerio)
      - Lysyl hydroxylases:Lysyl hydroxylase procollagen substrates [endoplasmic reticulum membrane] (Danio rerio)
        
        Lysyl hydroxylase procollagen substrates [endoplasmic reticulum lumen] (Danio rerio)
        
        4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Danio rerio)
        
        Homologues of 3x4Hyp-COL16A1 [endoplasmic reticulum lumen] (Danio rerio)
        
        col5a2a [endoplasmic reticulum lumen] (Danio rerio)
    - Procollagen triple helix formation (Danio rerio)
      - Collagen and procollagen triple helices:Serpin H1 [endoplasmic reticulum lumen] (Danio rerio)
        
        Collagen and procollagen triple helices [endoplasmic reticulum lumen] (Danio rerio)
        
        Non-fibrillar collagens [endoplasmic reticulum lumen] (Danio rerio)
        
        C-linked procollagen type XVI trimer [endoplasmic reticulum lumen] (Danio rerio)
        
        Alpha-1(XVI) chains [endoplasmic reticulum lumen] (Danio rerio)
        
        Homologues of 3x4Hyp-COL16A1 [endoplasmic reticulum lumen] (Danio rerio)
        
        col5a2a [endoplasmic reticulum lumen] (Danio rerio)
      - Procollagen C-linked trimers [endoplasmic reticulum lumen] (Danio rerio)
        
        C-linked procollagen type XVI trimer [endoplasmic reticulum lumen] (Danio rerio)
        
        Alpha-1(XVI) chains [endoplasmic reticulum lumen] (Danio rerio)
        
        Homologues of 3x4Hyp-COL16A1 [endoplasmic reticulum lumen] (Danio rerio)
        
        col5a2a [endoplasmic reticulum lumen] (Danio rerio)
    - Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines (Danio rerio)
      - 4-Hyp collagen propeptides:P4HB [endoplasmic reticulum lumen] (Danio rerio)
        
        4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Danio rerio)
        
        Homologues of 3x4Hyp-COL16A1 [endoplasmic reticulum lumen] (Danio rerio)
        
        col5a2a [endoplasmic reticulum lumen] (Danio rerio)
    - Secretion of collagens (Danio rerio)
      - Collagens and tropocollagens:Serpin H1 [endoplasmic reticulum lumen] (Danio rerio)
        
        Collagens and tropocollagens [endoplasmic reticulum lumen] (Danio rerio)
        
        Non-fibrillar collagens [endoplasmic reticulum lumen] (Danio rerio)
        
        C-linked procollagen type XVI trimer [endoplasmic reticulum lumen] (Danio rerio)
        
        Alpha-1(XVI) chains [endoplasmic reticulum lumen] (Danio rerio)
        
        Homologues of 3x4Hyp-COL16A1 [endoplasmic reticulum lumen] (Danio rerio)
        
        col5a2a [endoplasmic reticulum lumen] (Danio rerio)

External Reference Information

External Reference

UniProt:F1QT86

Gene Names

col5a2a

Reference Genes

ENSEMBL:ENSDARG00000031678

Other Identifiers

13269034

564821

A_15_P111574

A_15_P201966

A_15_P495557

A_15_P724011

CUST_25764_PI428451953

CUST_25765_PI428451953

CUST_25766_PI428451953

CUST_25767_PI428451953

DRER43216

Dr.741.1.S1_at

ENSDART00000033544

ENSDART00000033544_1

ENSDART00000033544_2

ENSDART00000041807

ENSDART00000048817

GO:0003674

GO:0005198

GO:0005201

GO:0005515

GO:0005575

GO:0005576

GO:0005588

GO:0005615

GO:0008150

GO:0030198

GO:0031012

GO:0032991

GO:0043167

GO:0046872

LOLS14471

MADDr01004942

MADDr01009612

OTTDART00000001874

OTTDART00000001971

TC238653

XM_678324

ZV700S00006112

Participant Of

hasMember

Homologues of 3x4Hyp-COL16A1 [endoplasmic reticulum lumen]

Other forms of this molecule

col5a2a [endoplasmic reticulum lumen]

col5a2a [extracellular region]

Inferred From

3x4Hyp-COL16A1 [endoplasmic reticulum lumen] (Homo sapiens)

Modified Residues

Name

(2S,4R)-4-hydroxyproline at unknown position

PsiMod Name

(2S,4R)-4-hydroxyproline

PsiMod Definition

A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline

Name

(2S,4R)-4-hydroxyproline at unknown position

PsiMod Name

(2S,4R)-4-hydroxyproline

PsiMod Definition

A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline

Name

(2S,4R)-4-hydroxyproline at unknown position

PsiMod Name

(2S,4R)-4-hydroxyproline

PsiMod Definition

A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline

Cross References

Ensembl

ENSDARG00000031678, ENSDART00000144744, ENSDARP00000122378