Reactome | phospho-irs4a [plasma membrane]

phospho-irs4a [plasma membrane]

Stable Identifier

R-DRE-2424302

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

plasma membrane

Synonyms

p-Y-IRS4, E7FCJ4

Locations in the PathwayBrowser

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Signal Transduction (Danio rerio)

- Signaling by Receptor Tyrosine Kinases (Danio rerio)
  - Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Danio rerio)
    - IGF1R signaling cascade (Danio rerio)
      - IRS-related events triggered by IGF1R (Danio rerio)
        
        IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 (Danio rerio)
        
        IGF1,2:p-IGF1R:p-IRS1,2,4 [plasma membrane] (Danio rerio)
        
        p-IRS1,2,4 [plasma membrane] (Danio rerio)
        
        phospho-irs4a [plasma membrane] (Danio rerio)

External Reference Information

External Reference

UniProt:E7FCJ4

Gene Names

irs4a

Reference Genes

BioGPS Gene:100329897 irs4a

CTD Gene:100329897 irs4a

ENSEMBL:ENSDARG00000086551

KEGG Gene (Danio rerio):100329897 irs4a

Monarch:100329897 irs4a

NCBI Gene:100329897 irs4a

Reference Transcript

RefSeq:XM_002666075.5 irs4a

Other Identifiers

100329897

13118486

A_15_P550982

CUST_19407_PI428451953

DRER27159

GO:0003674

GO:0005158

GO:0005575

GO:0005622

GO:0005737

GO:0005829

GO:0005886

GO:0007165

GO:0008150

GO:0008286

GO:0043548

JP011474

XM_687561

Participant Of

hasMember

p-IRS1,2,4 [plasma membrane]

Other forms of this molecule

irs4a [plasma membrane]

Inferred From

p-Y-IRS4 [plasma membrane] (Homo sapiens)

Modified Residues

Name

O4'-phospho-L-tyrosine at unknown position

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

RefSeq

XP_002666121.3

ZFIN

ZDB-GENE-120215-92

Ensembl

ENSDARP00000110181, ENSDART00000126092, ENSDARG00000086551

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