Reactome | phospho-btk [cytosol]

phospho-btk [cytosol]

Stable Identifier

R-DRE-2685603-2

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

cytosol

Synonyms

p-Y551-BTK, F8W3B7

Locations in the PathwayBrowser

Expand all

Immune System (Danio rerio)

- Innate Immune System (Danio rerio)
  - Fc epsilon receptor (FCERI) signaling (Danio rerio)
    - FCERI mediated Ca+2 mobilization (Danio rerio)
      - Autophosphorylation of BTK/ITK (Danio rerio)
        
        Homologues of p-Y551-BTK [cytosol] (Danio rerio)
        
        phospho-btk [cytosol] (Danio rerio)
        
        p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-TEC kinases:PIP3 [plasma membrane] (Danio rerio)
        
        p-TEC kinases [cytosol] (Danio rerio)
        
        Homologues of p-Y551-BTK [cytosol] (Danio rerio)
        
        phospho-btk [cytosol] (Danio rerio)
      - Hydrolysis of PIP2 by PLCG (Danio rerio)
        
        p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-2Y-BTK/p-2Y-ITK:PIP3 [plasma membrane] (Danio rerio)
        
        p-TEC kinases [cytosol] (Danio rerio)
        
        Homologues of p-Y551-BTK [cytosol] (Danio rerio)
        
        phospho-btk [cytosol] (Danio rerio)
      - Phosphorylation of TEC kinases by p-SYK (Danio rerio)
        
        p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-TEC kinases:PIP3 [plasma membrane] (Danio rerio)
        
        p-TEC kinases [cytosol] (Danio rerio)
        
        Homologues of p-Y551-BTK [cytosol] (Danio rerio)
        
        phospho-btk [cytosol] (Danio rerio)

External Reference Information

External Reference

UniProt:F8W3B7

Gene Names

btk

Reference Genes

BioGPS Gene:568653 btk

ENSEMBL:ENSDARG00000004433

Monarch:568653 btk

NCBI Gene:568653 btk

Reference Transcript

RefSeq:XM_691995.7 btk

Other Identifiers

13016595

13016597

568653

A_15_P108416

A_15_P452610

CJ006515

CJ006516

CJ007140

CJ007141

CJ011221

CJ011222

CJ012598

CJ013428

CJ013489

CUST_13360_PI428451953

CUST_7369_PI428451958

DRER01111

DRER46848

Dr.12317.1.A1_at

ENSDART00000009758

ENSDART00000009758_1

ENSDART00000009758_2

GO:0000166

GO:0002250

GO:0002376

GO:0003674

GO:0004672

GO:0004713

GO:0004715

GO:0005515

GO:0005524

GO:0006464

GO:0006468

GO:0007165

GO:0007267

GO:0008150

GO:0009952

GO:0016301

GO:0016310

GO:0016740

GO:0018108

GO:0030178

GO:0035556

GO:0043167

GO:0046872

GO:0048856

GO:0060828

GT_Spec_XM_691995.5_407775

JP006913

JP006914

JP007538

JP007539

XM_691995

XM_692197

ZV700S00000637

Participant Of

hasMember

Homologues of p-Y551-BTK [cytosol]

Other forms of this molecule

phospho-btk [cytosol]

phospho-btk [plasma membrane]

btk [cytosol]

Inferred From

p-Y551-BTK [cytosol] (Homo sapiens)

Modified Residues

Name

O4'-phospho-L-tyrosine at 551 (in Homo sapiens)

Coordinate

551

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

RefSeq

XP_697087.4

Ensembl

ENSDARG00000004433, ENSDART00000148737, ENSDARP00000124430