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VAV1,2,3 [cytosol]
Stable Identifier
R-DRE-430172
Type
Set [DefinedSet]
Species
Danio rerio
Compartment
cytosol
Synonyms
VAV1,VAV2,VAV3
Locations in the PathwayBrowser
Expand all
Developmental Biology (Danio rerio)
Nervous system development (Danio rerio)
Axon guidance (Danio rerio)
EPH-Ephrin signaling (Danio rerio)
EPH-ephrin mediated repulsion of cells (Danio rerio)
SFKs phosphorylate VAV2,3 (Danio rerio)
EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:VAV2,VAV3 [plasma membrane] (Danio rerio)
VAV1,2,3 [cytosol] (Danio rerio)
p-EPHs bind VAV2,3 (Danio rerio)
EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:VAV2,VAV3 [plasma membrane] (Danio rerio)
VAV1,2,3 [cytosol] (Danio rerio)
VAV1,2,3 [cytosol] (Danio rerio)
Hemostasis (Danio rerio)
Platelet activation, signaling and aggregation (Danio rerio)
GPVI-mediated activation cascade (Danio rerio)
p-SLP-76 binds VAV (Danio rerio)
VAV1,2,3 [cytosol] (Danio rerio)
p-SLP-76:VAV [cytosol] (Danio rerio)
VAV1,2,3 [cytosol] (Danio rerio)
Immune System (Danio rerio)
Innate Immune System (Danio rerio)
DAP12 interactions (Danio rerio)
DAP12 signaling (Danio rerio)
Phosphorylation of PLC-gamma by p-BTK/p-SYK (Danio rerio)
p-5Y-LAT:GRB2:SOS1:GADS:p-3Y-SLP-76:PLCG:VAV:p-Y223,Y551-BTK [plasma membrane] (Danio rerio)
VAV1,2,3 [cytosol] (Danio rerio)
p-5Y-LAT:GRB2:SOS:GADS:p-3Y-SLP-76:p-2Y-BTK:VAV:p-PLCG [plasma membrane] (Danio rerio)
VAV1,2,3 [cytosol] (Danio rerio)
Recruitment of VAV and BTK to p-SLP-76 (Danio rerio)
VAV1,2,3 [cytosol] (Danio rerio)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG:VAV:BTK:PIP3 [plasma membrane] (Danio rerio)
VAV1,2,3 [cytosol] (Danio rerio)
Release of p-PLCG1 (Danio rerio)
p-5Y-LAT:GRB2:SOS:GADS:p-3Y-SLP-76:p-2Y-BTK:VAV [plasma membrane] (Danio rerio)
VAV1,2,3 [cytosol] (Danio rerio)
p-5Y-LAT:GRB2:SOS:GADS:p-3Y-SLP-76:p-2Y-BTK:VAV:p-PLCG [plasma membrane] (Danio rerio)
VAV1,2,3 [cytosol] (Danio rerio)
Fc epsilon receptor (FCERI) signaling (Danio rerio)
FCERI mediated Ca+2 mobilization (Danio rerio)
Autophosphorylation of BTK/ITK (Danio rerio)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-2Y-TEC kinases [plasma membrane] (Danio rerio)
VAV1,2,3 [cytosol] (Danio rerio)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-TEC kinases:PIP3 [plasma membrane] (Danio rerio)
VAV1,2,3 [cytosol] (Danio rerio)
Hydrolysis of PIP2 by PLCG (Danio rerio)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-2Y-BTK/p-2Y-ITK:PIP3 [plasma membrane] (Danio rerio)
VAV1,2,3 [cytosol] (Danio rerio)
Phosphorylation of TEC kinases by p-SYK (Danio rerio)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:TEC kinases:PIP3 [plasma membrane] (Danio rerio)
VAV1,2,3 [cytosol] (Danio rerio)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-TEC kinases:PIP3 [plasma membrane] (Danio rerio)
VAV1,2,3 [cytosol] (Danio rerio)
FCERI mediated MAPK activation (Danio rerio)
Phosphorylation and activation of VAV (Danio rerio)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV [plasma membrane] (Danio rerio)
VAV1,2,3 [cytosol] (Danio rerio)
Recruitment of VAV to p-SLP-76 (Danio rerio)
VAV1,2,3 [cytosol] (Danio rerio)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV [plasma membrane] (Danio rerio)
VAV1,2,3 [cytosol] (Danio rerio)
Fcgamma receptor (FCGR) dependent phagocytosis (Danio rerio)
Regulation of actin dynamics for phagocytic cup formation (Danio rerio)
Phosphorylation of VAV (Danio rerio)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:VAV [plasma membrane] (Danio rerio)
VAV1,2,3 [cytosol] (Danio rerio)
Recruitment of VAV1 to p-6Y-SYK (Danio rerio)
VAV1,2,3 [cytosol] (Danio rerio)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:VAV [plasma membrane] (Danio rerio)
VAV1,2,3 [cytosol] (Danio rerio)
Signal Transduction (Danio rerio)
Signaling by Receptor Tyrosine Kinases (Danio rerio)
Signaling by VEGF (Danio rerio)
VEGFA-VEGFR2 Pathway (Danio rerio)
Src kinases phosphorylate VAV (Danio rerio)
PIP3:VAV1,2,3 [plasma membrane] (Danio rerio)
VAV1,2,3 [cytosol] (Danio rerio)
VAV exchanges GTP for GDP on RAC1, activating it (Danio rerio)
VAV1,2,3 [cytosol] (Danio rerio)
Participants
members
vav2 [cytosol] (Danio rerio)
vav3b [cytosol] (Danio rerio)
Participant Of
input
p-EPHs bind VAV2,3
p-SLP-76 binds VAV
Recruitment of VAV and BTK to p-SLP-76
Recruitment of VAV to p-SLP-76
Recruitment of VAV1 to p-6Y-SYK
hasComponent
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:VAV [plasma membrane]
EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:VAV2,VAV3 [plasma membrane]
p-5Y-LAT:GRB2:SOS1:GADS:p-3Y-SLP-76:PLCG:VAV:p-Y223,Y551-BTK [plasma membrane]
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG:VAV:BTK:PIP3 [plasma membrane]
p-5Y-LAT:GRB2:SOS:GADS:p-3Y-SLP-76:p-2Y-BTK:VAV [plasma membrane]
p-5Y-LAT:GRB2:SOS:GADS:p-3Y-SLP-76:p-2Y-BTK:VAV:p-PLCG [plasma membrane]
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV [plasma membrane]
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-2Y-BTK/p-2Y-ITK:PIP3 [plasma membrane]
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-2Y-TEC kinases [plasma membrane]
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-TEC kinases:PIP3 [plasma membrane]
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:TEC kinases:PIP3 [plasma membrane]
p-SLP-76:VAV [cytosol]
PIP3:VAV1,2,3 [plasma membrane]
Inferred From
VAV family [cytosol] (Homo sapiens)
VAV2,VAV3 [cytosol] (Homo sapiens)
VAV1,2,3 [cytosol] (Homo sapiens)
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