Reactome | il12rb2 [plasma membrane]

il12rb2 [plasma membrane]

Stable Identifier

R-DRE-449671-2

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

plasma membrane

Synonyms

IL13RA1, A8WH97

Locations in the PathwayBrowser

Expand all

Immune System (Danio rerio)

- Cytokine Signaling in Immune system (Danio rerio)
  - Signaling by Interleukins (Danio rerio)
    - Interleukin-4 and Interleukin-13 signaling (Danio rerio)
      - IL13RA1 binds TYK2 (Danio rerio)
        
        Homologues of IL13RA1 [plasma membrane] (Danio rerio)
        
        il12rb2 [plasma membrane] (Danio rerio)
        
        IL13RA1:TYK2 [plasma membrane] (Danio rerio)
        
        Homologues of IL13RA1 [plasma membrane] (Danio rerio)
        
        il12rb2 [plasma membrane] (Danio rerio)
      - IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated (Danio rerio)
        
        IL13:IL13RA:TYK2:IL4R:JAK2:JAK1 [plasma membrane] (Danio rerio)
        
        IL13:IL13RA:TYK2:IL4R:JAK2 [plasma membrane] (Danio rerio)
        
        IL13:IL13RA:TYK2 [plasma membrane] (Danio rerio)
        
        IL13RA1:TYK2 [plasma membrane] (Danio rerio)
        
        Homologues of IL13RA1 [plasma membrane] (Danio rerio)
        
        il12rb2 [plasma membrane] (Danio rerio)
      - JAK1 binds IL4R in IL13-bound IL13R type II (Danio rerio)
        
        IL13:IL13RA:TYK2:IL4R:JAK2 [plasma membrane] (Danio rerio)
        
        IL13:IL13RA:TYK2 [plasma membrane] (Danio rerio)
        
        IL13RA1:TYK2 [plasma membrane] (Danio rerio)
        
        Homologues of IL13RA1 [plasma membrane] (Danio rerio)
        
        il12rb2 [plasma membrane] (Danio rerio)
        
        IL13:IL13RA:TYK2:IL4R:JAK2:JAK1 [plasma membrane] (Danio rerio)
        
        IL13:IL13RA:TYK2:IL4R:JAK2 [plasma membrane] (Danio rerio)
        
        IL13:IL13RA:TYK2 [plasma membrane] (Danio rerio)
        
        IL13RA1:TYK2 [plasma membrane] (Danio rerio)
        
        Homologues of IL13RA1 [plasma membrane] (Danio rerio)
        
        il12rb2 [plasma membrane] (Danio rerio)
      - SOCS5,(SOCS1) bind IL4RA (Danio rerio)
        
        IL4:IL4R:JAK2:IL13RA1:TYK2 [plasma membrane] (Danio rerio)
        
        IL13RA1:TYK2 [plasma membrane] (Danio rerio)
        
        Homologues of IL13RA1 [plasma membrane] (Danio rerio)
        
        il12rb2 [plasma membrane] (Danio rerio)
        
        IL4:IL4R:JAK2:IL13RA:TYK2:SOCS5,(SOCS1) [plasma membrane] (Danio rerio)
        
        IL4:IL4R:JAK2:IL13RA1:TYK2 [plasma membrane] (Danio rerio)
        
        IL13RA1:TYK2 [plasma membrane] (Danio rerio)
        
        Homologues of IL13RA1 [plasma membrane] (Danio rerio)
        
        il12rb2 [plasma membrane] (Danio rerio)

External Reference Information

External Reference

UniProt:A8WH97

Gene Names

il12rb2

Reference Genes

BioGPS Gene:100134971 il12rb2

ENSEMBL:ENSDARG00000052157

KEGG Gene (Danio rerio):100134971 il12rb2

Monarch:100134971 il12rb2

NCBI Gene:100134971 il12rb2

Reference Transcript

RefSeq:NM_001113505.1 il12rb2

Other Identifiers

100134971

13221634

13302030

A_15_P222481

CJ002473

CJ002474

CJ002475

CUST_12449_PI428451958

CUST_20509_PI428451953

CUST_20595_PI428451953

DRER01994

DRER37650

DRER46823

ENSDART00000016388

GO:0003674

GO:0004896

GO:0005515

GO:0005575

GO:0005886

GO:0007165

GO:0008150

GO:0009897

GO:0016020

GO:0016021

GO:0019221

GO:0019955

GO:0032991

GO:0043235

GT_Spec_XM_002662478.2_107453

GT_Xhyb_NM_001113505.1_107462

JP002662

JP002663

JP002664

Participant Of

hasMember

Homologues of IL13RA1 [plasma membrane]

Other forms of this molecule

phospho-il12rb2 [plasma membrane]

il12rb2 [plasma membrane]

Inferred From

IL13RA1 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001106977.1

Ensembl

ENSDART00000016388, ENSDARP00000005204, ENSDARG00000052157