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What is Reactome ?
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K63-Ub [cytosol]
Stable Identifier
R-DRE-450143
Type
Set [DefinedSet]
Species
Danio rerio
Compartment
cytosol
Synonyms
K63-ubiquitin
Locations in the PathwayBrowser
Expand all
Immune System (Danio rerio)
Adaptive Immune System (Danio rerio)
TCR signaling (Danio rerio)
Downstream TCR signaling (Danio rerio)
Auto-ubiquitination of TRAF6 (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
Ubiquitination of NEMO by TRAF6 (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
Cytokine Signaling in Immune system (Danio rerio)
FLT3 Signaling (Danio rerio)
RAF/MAP kinase cascade (Danio rerio)
RAS processing (Danio rerio)
USP17L2 deubiquitinates RCE1 (Danio rerio)
PolyUb [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
Signaling by Interleukins (Danio rerio)
Interleukin-1 family signaling (Danio rerio)
Interleukin-1 signaling (Danio rerio)
Activated TAK1 mediates phosphorylation of the IKK Complex (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
Pellino ubiquitinates IRAK1 (Danio rerio)
hp-IRAK1: p-Pellino-1,2,(3):UBE2N:UBE2V1:K63polyUb [cytosol] (Danio rerio)
UBE2N:UBE2V1:K63polyUb [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Danio rerio)
Activated TAK1 mediates phosphorylation of the IKK Complex (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
TRAF6 is K63 poly-ubiquitinated (Danio rerio)
hp-IRAK1:3xTRAF6:3xUBE2N:UBE2V1:K63polyUb [cytosol] (Danio rerio)
UBE2N:UBE2V1:K63polyUb [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
hp-IRAK1:3xTRAF6 binds UBE2N:UBE2V1:K63-polyUb (Danio rerio)
UBE2N:UBE2V1:K63polyUb [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
hp-IRAK1:3xTRAF6:3xUBE2N:UBE2V1:K63polyUb [cytosol] (Danio rerio)
UBE2N:UBE2V1:K63polyUb [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
hp-IRAK1:p-Pellino, IRAK4:p-Pellino bind UBE2N:UBE2V1 (Danio rerio)
IRAK1:Pellino:E2 complexes [cytosol] (Danio rerio)
IRAK4: p-Pellino-1,2,3:UBE2N:UBE2V1:K63polyUb [cytosol] (Danio rerio)
UBE2N:UBE2V1:K63polyUb [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
hp-IRAK1: p-Pellino-1,2,(3):UBE2N:UBE2V1:K63polyUb [cytosol] (Danio rerio)
UBE2N:UBE2V1:K63polyUb [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
UBE2N:UBE2V1:K63polyUb [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
Interleukin-17 signaling (Danio rerio)
MAP kinase activation (Danio rerio)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Danio rerio)
Activated TAK1 phosphorylates MKK4/MKK7 (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
activated TAK1 mediates p38 MAPK activation (Danio rerio)
activated human TAK1 phosphorylates MKK3/MKK6 (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
TNFR2 non-canonical NF-kB pathway (Danio rerio)
TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
Innate Immune System (Danio rerio)
Alpha-protein kinase 1 signaling pathway (Danio rerio)
Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex (Danio rerio)
ALPK1:ADP-heptose:p-T9-TIFA:polyUb-TRAF6:TAK1:TAB1:TAB2/TAB3: free polyUb chain [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
ALPK1:ADP-heptose:p-T9-TIFA:polyUb-TRAF6:p-T184,T187-TAK1:TAB1:TAB2/TAB3: free polyUb chain [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
C-type lectin receptors (CLRs) (Danio rerio)
CLEC7A (Dectin-1) signaling (Danio rerio)
K63polyUb-TRAF6 ubiquitinates TAK1 (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
TRAF6 oligomer autoubiquitinates (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
Ubiquitination of NEMO by TRAF6 (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
Fc epsilon receptor (FCERI) signaling (Danio rerio)
FCERI mediated NF-kB activation (Danio rerio)
Auto-ubiquitination of TRAF6 (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
Ubiquitination of NEMO by TRAF6 (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways (Danio rerio)
NOD1/2 Signaling Pathway (Danio rerio)
Activated TAK1 mediates phosphorylation of the IKK Complex (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
CYLD deubiquitinates NEMO (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PAMP:NOD oligomer:RIP2:K63-pUb-K285-NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
K63 polyubiquitinated RIP2 associates with the TAK1 complex (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:TAK1 complex [plasma membrane] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
RIP2 induces K63-linked ubiquitination of NEMO (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PAMP:NOD oligomer:RIP2:K63-pUb-K285-NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
RIP2 is K63 polyubiquitinated (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
TAK1 is activated (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:TAK1 complex [plasma membrane] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
TNFAIP3 (A20) deubiquitinates RIP2 (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
Toll-like Receptor Cascades (Danio rerio)
Toll Like Receptor 10 (TLR10) Cascade (Danio rerio)
MyD88 cascade initiated on plasma membrane (Danio rerio)
IRAK1 recruits IKK complex (Danio rerio)
Pellino ubiquitinates hp-IRAK1 (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
IRAK2 mediated activation of TAK1 complex (Danio rerio)
Activated TRAF6 synthesizes unanchored polyubiquitin chains (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [plasma membrane] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
MAP kinase activation (Danio rerio)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Danio rerio)
Activated TAK1 phosphorylates MKK4/MKK7 (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
activated TAK1 mediates p38 MAPK activation (Danio rerio)
activated human TAK1 phosphorylates MKK3/MKK6 (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Danio rerio)
Activated TAK1 mediates phosphorylation of the IKK Complex (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
Toll Like Receptor 2 (TLR2) Cascade (Danio rerio)
Toll Like Receptor TLR1:TLR2 Cascade (Danio rerio)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Danio rerio)
IRAK1 recruits IKK complex (Danio rerio)
Pellino ubiquitinates hp-IRAK1 (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
IRAK2 mediated activation of TAK1 complex (Danio rerio)
Activated TRAF6 synthesizes unanchored polyubiquitin chains (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [plasma membrane] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
MAP kinase activation (Danio rerio)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Danio rerio)
Activated TAK1 phosphorylates MKK4/MKK7 (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
activated TAK1 mediates p38 MAPK activation (Danio rerio)
activated human TAK1 phosphorylates MKK3/MKK6 (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Danio rerio)
Activated TAK1 mediates phosphorylation of the IKK Complex (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
Toll Like Receptor TLR6:TLR2 Cascade (Danio rerio)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Danio rerio)
IRAK1 recruits IKK complex (Danio rerio)
Pellino ubiquitinates hp-IRAK1 (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
IRAK2 mediated activation of TAK1 complex (Danio rerio)
Activated TRAF6 synthesizes unanchored polyubiquitin chains (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [plasma membrane] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
MAP kinase activation (Danio rerio)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Danio rerio)
Activated TAK1 phosphorylates MKK4/MKK7 (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
activated TAK1 mediates p38 MAPK activation (Danio rerio)
activated human TAK1 phosphorylates MKK3/MKK6 (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Danio rerio)
Activated TAK1 mediates phosphorylation of the IKK Complex (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
Toll Like Receptor 3 (TLR3) Cascade (Danio rerio)
MAP kinase activation (Danio rerio)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Danio rerio)
Activated TAK1 phosphorylates MKK4/MKK7 (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
activated TAK1 mediates p38 MAPK activation (Danio rerio)
activated human TAK1 phosphorylates MKK3/MKK6 (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Danio rerio)
Activated TAK1 mediates phosphorylation of the IKK Complex (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
Toll Like Receptor 4 (TLR4) Cascade (Danio rerio)
MyD88-independent TLR4 cascade (Danio rerio)
TRIF(TICAM1)-mediated TLR4 signaling (Danio rerio)
MAP kinase activation (Danio rerio)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Danio rerio)
Activated TAK1 phosphorylates MKK4/MKK7 (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
activated TAK1 mediates p38 MAPK activation (Danio rerio)
activated human TAK1 phosphorylates MKK3/MKK6 (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Danio rerio)
Activated TAK1 mediates phosphorylation of the IKK Complex (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
TRAF6-mediated induction of TAK1 complex within TLR4 complex (Danio rerio)
Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
Activation of TAK1 complex bound to activated TLR4 complex (Danio rerio)
activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:activated TAK1 complex [endosome membrane] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Danio rerio)
IRAK1 recruits IKK complex (Danio rerio)
Pellino ubiquitinates hp-IRAK1 (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
IRAK2 mediated activation of TAK1 complex (Danio rerio)
Activated TRAF6 synthesizes unanchored polyubiquitin chains (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [plasma membrane] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
MAP kinase activation (Danio rerio)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Danio rerio)
Activated TAK1 phosphorylates MKK4/MKK7 (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
activated TAK1 mediates p38 MAPK activation (Danio rerio)
activated human TAK1 phosphorylates MKK3/MKK6 (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Danio rerio)
Activated TAK1 mediates phosphorylation of the IKK Complex (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
Toll Like Receptor 5 (TLR5) Cascade (Danio rerio)
MyD88 cascade initiated on plasma membrane (Danio rerio)
IRAK1 recruits IKK complex (Danio rerio)
Pellino ubiquitinates hp-IRAK1 (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
IRAK2 mediated activation of TAK1 complex (Danio rerio)
Activated TRAF6 synthesizes unanchored polyubiquitin chains (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [plasma membrane] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
MAP kinase activation (Danio rerio)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Danio rerio)
Activated TAK1 phosphorylates MKK4/MKK7 (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
activated TAK1 mediates p38 MAPK activation (Danio rerio)
activated human TAK1 phosphorylates MKK3/MKK6 (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Danio rerio)
Activated TAK1 mediates phosphorylation of the IKK Complex (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Danio rerio)
MyD88 dependent cascade initiated on endosome (Danio rerio)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Danio rerio)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation (Danio rerio)
Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation
(Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Danio rerio)
Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex upon TLR7/8 or 9 stimulation (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [endosome membrane] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [endosome membrane] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [endosome membrane] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
MAP kinase activation (Danio rerio)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Danio rerio)
Activated TAK1 phosphorylates MKK4/MKK7 (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
activated TAK1 mediates p38 MAPK activation (Danio rerio)
activated human TAK1 phosphorylates MKK3/MKK6 (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Danio rerio)
Activated TAK1 mediates phosphorylation of the IKK Complex (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
Toll Like Receptor 9 (TLR9) Cascade (Danio rerio)
MyD88 dependent cascade initiated on endosome (Danio rerio)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Danio rerio)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation (Danio rerio)
Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation
(Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Danio rerio)
Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex upon TLR7/8 or 9 stimulation (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [endosome membrane] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [endosome membrane] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [endosome membrane] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
MAP kinase activation (Danio rerio)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Danio rerio)
Activated TAK1 phosphorylates MKK4/MKK7 (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
activated TAK1 mediates p38 MAPK activation (Danio rerio)
activated human TAK1 phosphorylates MKK3/MKK6 (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Danio rerio)
Activated TAK1 mediates phosphorylation of the IKK Complex (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
Metabolism of proteins (Danio rerio)
Post-translational protein modification (Danio rerio)
Deubiquitination (Danio rerio)
Josephin domain DUBs (Danio rerio)
ATXN3 deubiquitinates polyUb-PARK2 (Danio rerio)
PolyUb [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
ATXN3 family cleave Ub chains (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PARK2 autoubiquitinates (Danio rerio)
PolyUb [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
Metalloprotease DUBs (Danio rerio)
BRISC complex deubiquitinates NLRP3 (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PSMD14 cleaves K63-linked ubiquitin (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
STAMBPL1 is a deubiquitinase (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
Ovarian tumor domain proteases (Danio rerio)
TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1 (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
TNFAIP3 (A20) deubiquitinates RIP2 (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
Ub-specific processing proteases (Danio rerio)
CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
USP10 deubiquitinates SNX3, CFTR (Danio rerio)
PolyUb [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
USP11 deubiquitinates NFKBIA (Danio rerio)
PolyUb [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
USP13 deubiquitinates BECN1,USP10 (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 (Danio rerio)
PolyUb [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
USP18 deubiquitinates TAK1:TAB1 (Danio rerio)
PolyUb [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
USP19 deubiquitinates RNF123 (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
USP20, USP33 deubiquitinate ADRB2 (Danio rerio)
PolyUb [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
USP21 deubiquitinates RIPK1,DDX58 (Danio rerio)
PolyUb [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
USP33 deubiquitinates CCP110,ARRB (Danio rerio)
PolyUb [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
USP4 deubiquitinate TRAF2,TRAF6 (Danio rerio)
PolyUb [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
USP5 cleaves polyubiquitin (Danio rerio)
USP5:PolyUb [cytosol] (Danio rerio)
PolyUb [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
Signal Transduction (Danio rerio)
Death Receptor Signalling (Danio rerio)
TNF signaling (Danio rerio)
TNFR1-induced NFkappaB signaling pathway (Danio rerio)
BIRC(cIAP1/2) ubiquitinates RIPK1 (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
MAPK family signaling cascades (Danio rerio)
MAPK1/MAPK3 signaling (Danio rerio)
RAF/MAP kinase cascade (Danio rerio)
RAS processing (Danio rerio)
USP17L2 deubiquitinates RCE1 (Danio rerio)
PolyUb [cytosol] (Danio rerio)
K63polyUb [cytosol] (Danio rerio)
K63-Ub [cytosol] (Danio rerio)
Participants
members
rps27a [cytosol] (Danio rerio)
uba52 [cytosol] (Danio rerio)
Ub-63-UBB(1-76) [cytosol] (Danio rerio)
Ub-139-UBB(77-152) [cytosol] (Danio rerio)
Ub-215-UBB(153-228) [cytosol] (Danio rerio)
ubc [cytosol] (Danio rerio)
Participant Of
output
ATXN3 family cleave Ub chains
PSMD14 cleaves K63-linked ubiquitin
STAMBPL1 is a deubiquitinase
repeatedUnit
K63polyUb [cytosol]
Inferred From
K63-Ub [cytosol] (Homo sapiens)
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