Reactome | hist2h2l [nucleoplasm]

hist2h2l [nucleoplasm]

Stable Identifier

R-DRE-4568647-6

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

nucleoplasm

Synonyms

AcK22-HIST1H2BA, Q6PC60

Locations in the PathwayBrowser

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Chromatin organization (Danio rerio)

- Chromatin modifying enzymes (Danio rerio)
  - HATs acetylate histones (Danio rerio)
    - EP300 acetylates histone H2A, H2B, H3, H4 (Danio rerio)
      - AcK-histone H2A, H2B, H3, H4 [nucleoplasm] (Danio rerio)
        
        AcK(6,13,16,21)- histone H2B [nucleoplasm] (Danio rerio)
        
        AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Danio rerio)
        
        AcK(7,14,17,22)-HIST1H2BA [nucleoplasm] (Danio rerio)
        
        Homologues of AcK22-HIST1H2BA [nucleoplasm] (Danio rerio)
        
        hist2h2l [nucleoplasm] (Danio rerio)
  - HDACs deacetylate histones (Danio rerio)
    - HDAC10 deacetylates histone (Danio rerio)
      - Acetylated core histone octamer [nucleoplasm] (Danio rerio)
        
        Acetylated histone H2A:H2B [nucleoplasm] (Danio rerio)
        
        AcK(6,13,16,21)- histone H2B [nucleoplasm] (Danio rerio)
        
        AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Danio rerio)
        
        AcK(7,14,17,22)-HIST1H2BA [nucleoplasm] (Danio rerio)
        
        Homologues of AcK22-HIST1H2BA [nucleoplasm] (Danio rerio)
        
        hist2h2l [nucleoplasm] (Danio rerio)
    - HDAC1:2-containing complex deacetylate histones (Danio rerio)
      - Acetylated core histone octamer [nucleoplasm] (Danio rerio)
        
        Acetylated histone H2A:H2B [nucleoplasm] (Danio rerio)
        
        AcK(6,13,16,21)- histone H2B [nucleoplasm] (Danio rerio)
        
        AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Danio rerio)
        
        AcK(7,14,17,22)-HIST1H2BA [nucleoplasm] (Danio rerio)
        
        Homologues of AcK22-HIST1H2BA [nucleoplasm] (Danio rerio)
        
        hist2h2l [nucleoplasm] (Danio rerio)
    - HDAC3 containing complexes deacetylate histone (Danio rerio)
      - Acetylated core histone octamer [nucleoplasm] (Danio rerio)
        
        Acetylated histone H2A:H2B [nucleoplasm] (Danio rerio)
        
        AcK(6,13,16,21)- histone H2B [nucleoplasm] (Danio rerio)
        
        AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Danio rerio)
        
        AcK(7,14,17,22)-HIST1H2BA [nucleoplasm] (Danio rerio)
        
        Homologues of AcK22-HIST1H2BA [nucleoplasm] (Danio rerio)
        
        hist2h2l [nucleoplasm] (Danio rerio)
    - HDAC8 deacetylates histones (Danio rerio)
      - Acetylated core histone octamer [nucleoplasm] (Danio rerio)
        
        Acetylated histone H2A:H2B [nucleoplasm] (Danio rerio)
        
        AcK(6,13,16,21)- histone H2B [nucleoplasm] (Danio rerio)
        
        AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Danio rerio)
        
        AcK(7,14,17,22)-HIST1H2BA [nucleoplasm] (Danio rerio)
        
        Homologues of AcK22-HIST1H2BA [nucleoplasm] (Danio rerio)
        
        hist2h2l [nucleoplasm] (Danio rerio)

External Reference Information

External Reference

UniProt:Q6PC60

Gene Names

hist2h2l

Reference Genes

BioGPS Gene:386920 hist2h2l

CTD Gene:386920 hist2h2l

ENSEMBL:ENSDARG00000068996

ENSEMBL:ENSDARG00000112150 hist2h2l

KEGG Gene (Danio rerio):386920 hist2h2l

Monarch:386920 hist2h2l

NCBI Gene:386920 hist2h2l

Reference Transcript

RefSeq:NM_200117.1 hist2h2l

Other Identifiers

12969381

13282086

386920

A_15_P157991

BC059463.1

DRER07199

Dr.24294.1.A1_at

Dr.5231.1.S1_at

ENSDART00000055913

ENSDART00000055913_1

ENSDART00000055913_2

GO:0000786

GO:0003674

GO:0003677

GO:0005575

GO:0005622

GO:0005694

GO:0032991

GO:0043226

GO:0046982

LOLS10790

MADDr01005078

NM_200117

OTTDART00000009607

TC238221

ZV700S00004146

Participates

as a member of

Homologues of AcK22-HIST1H2BA [nucleoplasm] (Danio rerio)

Other forms of this molecule

hist2h2l [nucleoplasm]

Inferred From

AcK22-HIST1H2BA [nucleoplasm] (Homo sapiens)

Modified Residues

Name

N6-acetyl-L-lysine at 22 (in Homo sapiens)

Coordinate

PsiMod Name

N6-acetyl-L-lysine [MOD:00064]

PsiMod Definition

A protein modification that effectively converts an L-lysine residue to N6-acetyl-L-lysine.

Cross References

RefSeq

NP_956411.1

Ensembl

ENSDART00000186233, ENSDARG00000112150, ENSDARP00000156959, ENSDARP00000055912, ENSDARG00000068996, ENSDART00000055913

PRO

Q6PC60