Reactome | RHOA:GTP [plasma membrane]

RHOA:GTP [plasma membrane]

Stable Identifier

R-DRE-5665993

Type

Complex

Species

Danio rerio

Compartment

plasma membrane

Locations in the PathwayBrowser

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

GTP [cytosol]
RHOA [plasma membrane] (Danio rerio)

Participates

as an input of

RHOA GAPs stimulate RHOA GTPase activity (Danio rerio)
RHOA binds effectors at the plasma membrane (Danio rerio)
RHOA:GTP translocates to the ER membrane (Danio rerio)
RHOA:GTP binds RHPN1 or RHPN2 (Danio rerio)
Inactivation of Rho-GTP by p190RhoGAP (Danio rerio)
RHOA:GTP:Mg2+ binds ROCK1,ROCK2 (Danio rerio)
RHOA:GTP binds ROCK, activating it (Danio rerio)
ROCK activation by RHO (Danio rerio)
ARHGAP35 binds RHOA:GTP (Danio rerio)

as a component of

RHOA:GTP:cytosolic RHOA effectors [plasma membrane] (Danio rerio)
RHOA:GTP:RHPN1,RHPN2 [plasma membrane] (Danio rerio)
Activated ROCK:RhoA/B/C:GTP [plasma membrane] (Danio rerio)
p-Y1105-ARHGAP35:RHOA:GTP [cytosol] (Danio rerio)

as an output of

RHOA GEFs activate RHOA (Danio rerio)
NGEF exchanges GTP for GDP on RHOA (Danio rerio)
Activation of Rho by LARG and PDZ-RhoGEF (Danio rerio)
GEFs activate RhoA,B,C (Danio rerio)

Inferred From

RHOA/B/C:GTP [plasma membrane] (Homo sapiens)

RHOA:GTP [plasma membrane] (Homo sapiens)

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