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ERCC3 [nucleoplasm]
Stable Identifier
R-DRE-67439
Type
Protein [EntityWithAccessionedSequence]
Species
Danio rerio
Compartment
nucleoplasm
Synonyms
Q7ZVV1
Locations in the PathwayBrowser
Expand all
DNA Repair (Danio rerio)
Nucleotide Excision Repair (Danio rerio)
Global Genome Nucleotide Excision Repair (GG-NER) (Danio rerio)
Dual Incision in GG-NER (Danio rerio)
5'- incision of DNA by ERCC1:ERCC4 in GG-NER (Danio rerio)
GG-NER incision complex:5'-incised damaged DNA [nucleoplasm] (Danio rerio)
TFIIH Core [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
GG-NER incision complex:Open bubble dsDNA [nucleoplasm] (Danio rerio)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Danio rerio)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Danio rerio)
TFIIH Core [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
Formation of Incision Complex in GG-NER (Danio rerio)
Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER (Danio rerio)
GG-NER incision complex:Open bubble dsDNA [nucleoplasm] (Danio rerio)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Danio rerio)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Danio rerio)
TFIIH Core [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Danio rerio)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Danio rerio)
TFIIH Core [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
CHD1L is recruited to GG-NER site (Danio rerio)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Danio rerio)
TFIIH Core [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Danio rerio)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Danio rerio)
TFIIH Core [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA (Danio rerio)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Danio rerio)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Danio rerio)
TFIIH Core [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Danio rerio)
TFIIH Core [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
TFIIH binds GG-NER site to form a verification complex (Danio rerio)
TFIIH [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Danio rerio)
TFIIH [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
Transcription-Coupled Nucleotide Excision Repair (TC-NER) (Danio rerio)
Dual incision in TC-NER (Danio rerio)
5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER (Danio rerio)
TC-NER incision complex [nucleoplasm] (Danio rerio)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Danio rerio)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Danio rerio)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Danio rerio)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Danio rerio)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Danio rerio)
TFIIH [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Danio rerio)
TFIIH [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER (Danio rerio)
TC-NER incision complex [nucleoplasm] (Danio rerio)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Danio rerio)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Danio rerio)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Danio rerio)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Danio rerio)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Danio rerio)
TFIIH [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Danio rerio)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Danio rerio)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Danio rerio)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Danio rerio)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Danio rerio)
TFIIH [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
ERCC2-facilitated RNA Pol II backtracking in TC-NER (Danio rerio)
TC-NER pre-incision complex [nucleoplasm] (Danio rerio)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Danio rerio)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Danio rerio)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Danio rerio)
TFIIH [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Danio rerio)
Ubiquitinated,hyperphosphorylated RNA Pol II:Partially open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Danio rerio)
Ubiquitinated,hyperphosphorylated RNA Pol II:Partially open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Danio rerio)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Danio rerio)
TFIIH [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
ERCC3-facilitated RNA Pol II backtracking in TC-NER (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Danio rerio)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Danio rerio)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Danio rerio)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Danio rerio)
TFIIH [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Danio rerio)
Ubiquitinated,hyperphosphorylated RNA Pol II:Partially open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Danio rerio)
Ubiquitinated,hyperphosphorylated RNA Pol II:Partially open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Danio rerio)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Danio rerio)
TFIIH [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
Formation of TC-NER Pre-Incision Complex (Danio rerio)
UVSSA:USP7 deubiquitinates ERCC6 (Danio rerio)
TC-NER pre-incision complex [nucleoplasm] (Danio rerio)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Danio rerio)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Danio rerio)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Danio rerio)
TFIIH [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1:UVSSA:USP7:XAB2 complex:XPA:TCEA1:HMGN1:EP300 [nucleoplasm] (Danio rerio)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Danio rerio)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6 [nucleoplasm] (Danio rerio)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Danio rerio)
TFIIH [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
Gene expression (Transcription) (Danio rerio)
RNA Polymerase II Transcription (Danio rerio)
Generic Transcription Pathway (Danio rerio)
Transcriptional Regulation by TP53 (Danio rerio)
TP53 Regulates Transcription of DNA Repair Genes (Danio rerio)
CDK12 phosphorylates RNA Pol II CTD at DNA repair genes (Danio rerio)
CCNK:CDK12:CDK12-Phosphorylated Elongation Complex at DNA repair genes [nucleoplasm] (Danio rerio)
CDK12-Phosphorylated Elongation Complex [nucleoplasm] (Danio rerio)
TFIIH [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
CCNK:CDK12:Elongation Complex at DNA Repair Genes [nucleoplasm] (Danio rerio)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Danio rerio)
TFIIH [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
RNA Pol II CTD phosphorylation and interaction with CE (Danio rerio)
Activation of GT (Danio rerio)
RNA Pol II with phosphorylated CTD: CE complex [nucleoplasm] (Danio rerio)
TFIIH [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex (Danio rerio)
Pol II transcription complex containing extruded transcript to +30 [nucleoplasm] (Danio rerio)
TFIIH [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
Phosphorylation (Ser5) of RNA pol II CTD (Danio rerio)
Pol II transcription complex containing extruded transcript to +30 [nucleoplasm] (Danio rerio)
TFIIH [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
Pol II transcription complex with (ser5) phosphorylated CTD containing extruded transcript to +30 [nucleoplasm] (Danio rerio)
TFIIH [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
RNA Polymerase II CTD (phosphorylated) binds to CE (Danio rerio)
Pol II transcription complex with (ser5) phosphorylated CTD containing extruded transcript to +30 [nucleoplasm] (Danio rerio)
TFIIH [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
RNA Pol II with phosphorylated CTD: CE complex [nucleoplasm] (Danio rerio)
TFIIH [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (Danio rerio)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Danio rerio)
TFIIH [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
RNA Pol II with phosphorylated CTD: CE complex [nucleoplasm] (Danio rerio)
TFIIH [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
Metabolism of RNA (Danio rerio)
mRNA Capping (Danio rerio)
Activation of GT (Danio rerio)
RNA Pol II with phosphorylated CTD: CE complex [nucleoplasm] (Danio rerio)
TFIIH [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
Capping complex formation (Danio rerio)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Danio rerio)
TFIIH [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
Capping complex (initial) [nucleoplasm] (Danio rerio)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Danio rerio)
TFIIH [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
Dissociation of transcript with 5'-GMP from GT (Danio rerio)
Capping complex (GpppN..) [nucleoplasm] (Danio rerio)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Danio rerio)
TFIIH [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
Capping complex (with freed 5'- GMP) [nucleoplasm] (Danio rerio)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Danio rerio)
TFIIH [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
Formation of the CE:GMP intermediate complex (Danio rerio)
Capping complex (intermediate) [nucleoplasm] (Danio rerio)
Covalent CE:GMP intermediate complex [nucleoplasm] (Danio rerio)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Danio rerio)
TFIIH [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
Capping complex (hydrolyzed) [nucleoplasm] (Danio rerio)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Danio rerio)
TFIIH [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme (Danio rerio)
Capping complex (hydrolyzed) [nucleoplasm] (Danio rerio)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Danio rerio)
TFIIH [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
Capping complex (initial) [nucleoplasm] (Danio rerio)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Danio rerio)
TFIIH [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
RNA Polymerase II CTD (phosphorylated) binds to CE (Danio rerio)
Pol II transcription complex with (ser5) phosphorylated CTD containing extruded transcript to +30 [nucleoplasm] (Danio rerio)
TFIIH [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
RNA Pol II with phosphorylated CTD: CE complex [nucleoplasm] (Danio rerio)
TFIIH [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (Danio rerio)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Danio rerio)
TFIIH [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
RNA Pol II with phosphorylated CTD: CE complex [nucleoplasm] (Danio rerio)
TFIIH [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA (Danio rerio)
Capping complex (intermediate) [nucleoplasm] (Danio rerio)
Covalent CE:GMP intermediate complex [nucleoplasm] (Danio rerio)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Danio rerio)
TFIIH [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
Capping complex (GpppN..) [nucleoplasm] (Danio rerio)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Danio rerio)
TFIIH [nucleoplasm] (Danio rerio)
ERCC3 [nucleoplasm] (Danio rerio)
External Reference Information
External Reference
UniProt:Q7ZVV1
Reference Genes
BioGPS Gene:324323
ENSEMBL:ENSDARG00000002402
KEGG Gene (Danio rerio):324323
Monarch:324323
NCBI Gene:324323
Reference Transcript
RefSeq:NM_201582.1
Participates
as a component of
TFIIH Core [nucleoplasm] (Danio rerio)
TFIIH [nucleoplasm] (Danio rerio)
Inferred From
ERCC3 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_963876.1
ZFIN
ZDB-GENE-030131-3043
PRO
Q7ZVV1
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