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zgc:92282 [cytosol]
Stable Identifier
R-DRE-68744
Type
Protein [EntityWithAccessionedSequence]
Species
Danio rerio
Compartment
cytosol
Synonyms
PSMB2, Q6DHI9
Locations in the PathwayBrowser
Expand all
Cell Cycle (Danio rerio)
Cell Cycle Checkpoints (Danio rerio)
G1/S DNA Damage Checkpoints (Danio rerio)
p53-Dependent G1/S DNA damage checkpoint (Danio rerio)
p53-Dependent G1 DNA Damage Response (Danio rerio)
Stabilization of p53 (Danio rerio)
Autodegradation of the E3 ubiquitin ligase COP1 (Danio rerio)
Proteasome mediated degradation of COP1 (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
zgc:92282 [cytosol] (Danio rerio)
G2/M Checkpoints (Danio rerio)
GTSE1 facilitates proteasome-mediated degradation of TP53 (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
zgc:92282 [cytosol] (Danio rerio)
Cell Cycle, Mitotic (Danio rerio)
Mitotic G2-G2/M phases (Danio rerio)
G2/M Transition (Danio rerio)
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis (Danio rerio)
Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
zgc:92282 [cytosol] (Danio rerio)
Proteasome-mediated degradation of PolyUb-FBXL7 (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
zgc:92282 [cytosol] (Danio rerio)
The role of GTSE1 in G2/M progression after G2 checkpoint (Danio rerio)
GTSE1 facilitates proteasome-mediated degradation of TP53 (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
zgc:92282 [cytosol] (Danio rerio)
S Phase (Danio rerio)
Synthesis of DNA (Danio rerio)
Switching of origins to a post-replicative state (Danio rerio)
CDK-mediated phosphorylation and removal of Cdc6 (Danio rerio)
Ubiquitinated Cdc6 is degraded by the proteasome (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
zgc:92282 [cytosol] (Danio rerio)
Ubiquitin-dependent degradation of Cyclin D (Danio rerio)
Proteasome mediated degradation of Cyclin D1 (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
zgc:92282 [cytosol] (Danio rerio)
Cellular responses to stimuli (Danio rerio)
Cellular responses to stress (Danio rerio)
Cellular response to chemical stress (Danio rerio)
KEAP1-NFE2L2 pathway (Danio rerio)
26S proteasome degrades Ub-NFE2L2 (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
zgc:92282 [cytosol] (Danio rerio)
ub UBXN7 is degraded by the 26S proteasome (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
zgc:92282 [cytosol] (Danio rerio)
DNA Replication (Danio rerio)
Synthesis of DNA (Danio rerio)
Switching of origins to a post-replicative state (Danio rerio)
CDK-mediated phosphorylation and removal of Cdc6 (Danio rerio)
Ubiquitinated Cdc6 is degraded by the proteasome (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
zgc:92282 [cytosol] (Danio rerio)
Gene expression (Transcription) (Danio rerio)
RNA Polymerase II Transcription (Danio rerio)
Generic Transcription Pathway (Danio rerio)
Transcriptional regulation by RUNX1 (Danio rerio)
RUNX1 regulates transcription of genes involved in differentiation of HSCs (Danio rerio)
26S proteasome degrades TP73 polyubiquitinated by ITCH (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
zgc:92282 [cytosol] (Danio rerio)
Immune System (Danio rerio)
Adaptive Immune System (Danio rerio)
Class I MHC mediated antigen processing & presentation (Danio rerio)
Antigen processing-Cross presentation (Danio rerio)
Cross-presentation of soluble exogenous antigens (endosomes) (Danio rerio)
Proteasomal clevage of exogenous antigen (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
zgc:92282 [cytosol] (Danio rerio)
Antigen processing: Ubiquitination & Proteasome degradation (Danio rerio)
Proteasomal cleavage of substrate (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
zgc:92282 [cytosol] (Danio rerio)
Signaling by the B Cell Receptor (BCR) (Danio rerio)
Downstream signaling events of B Cell Receptor (BCR) (Danio rerio)
Activation of NF-kappaB in B cells (Danio rerio)
Ubiquitinated IkB is degraded (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
zgc:92282 [cytosol] (Danio rerio)
Metabolism (Danio rerio)
Metabolism of amino acids and derivatives (Danio rerio)
Metabolism of polyamines (Danio rerio)
Regulation of ornithine decarboxylase (ODC) (Danio rerio)
26S proteosome degrades ODC holoenzyme complex (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
zgc:92282 [cytosol] (Danio rerio)
Metabolism of RNA (Danio rerio)
Regulation of mRNA stability by proteins that bind AU-rich elements (Danio rerio)
AUF1 (hnRNP D0) binds and destabilizes mRNA (Danio rerio)
AUF1:mRNA complex is destroyed (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
zgc:92282 [cytosol] (Danio rerio)
Metabolism of proteins (Danio rerio)
Post-translational protein modification (Danio rerio)
Deubiquitination (Danio rerio)
UCH proteinases (Danio rerio)
ADRM1 binds 26S proteasome (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
zgc:92282 [cytosol] (Danio rerio)
ADRM1:26S proteasome [cytosol] (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
zgc:92282 [cytosol] (Danio rerio)
ADRM1:26S proteaseome binds UCHL5 (Danio rerio)
ADRM1:26S proteasome [cytosol] (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
zgc:92282 [cytosol] (Danio rerio)
ADRM1:26S proteasome:UCHL5 [cytosol] (Danio rerio)
ADRM1:26S proteasome [cytosol] (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
zgc:92282 [cytosol] (Danio rerio)
Ub-specific processing proteases (Danio rerio)
ADRM1:26S proteaseome binds USP14 (Danio rerio)
ADRM1:26S proteasome [cytosol] (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
zgc:92282 [cytosol] (Danio rerio)
ADRM1:26S proteasome:USP14 [cytosol] (Danio rerio)
ADRM1:26S proteasome [cytosol] (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
zgc:92282 [cytosol] (Danio rerio)
Neddylation (Danio rerio)
26S proteasome degrades HIFalpha (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
zgc:92282 [cytosol] (Danio rerio)
26S proteasome degrades Ub-NFE2L2 (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
zgc:92282 [cytosol] (Danio rerio)
ub UBXN7 is degraded by the 26S proteasome (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
zgc:92282 [cytosol] (Danio rerio)
Signal Transduction (Danio rerio)
Intracellular signaling by second messengers (Danio rerio)
PIP3 activates AKT signaling (Danio rerio)
PTEN Regulation (Danio rerio)
Regulation of PTEN stability and activity (Danio rerio)
Proteasome degrades polyubiquitinated PTEN (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
zgc:92282 [cytosol] (Danio rerio)
MAPK family signaling cascades (Danio rerio)
MAPK6/MAPK4 signaling (Danio rerio)
MAPK6 is degraded by the 26S proteasome (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
zgc:92282 [cytosol] (Danio rerio)
Signaling by Hedgehog (Danio rerio)
Hedgehog 'off' state (Danio rerio)
Degradation of GLI1 by the proteasome (Danio rerio)
GLI1 is degraded by the proteasome after ubiquitination by ITCH (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
zgc:92282 [cytosol] (Danio rerio)
GLI3 is processed to GLI3R by the proteasome (Danio rerio)
GLI3 is partially degraded by the proteasome to yield the GLI3 repressor (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
zgc:92282 [cytosol] (Danio rerio)
Hedgehog ligand biogenesis (Danio rerio)
Hh C-terminal fragments are degraded by the proteasome (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
zgc:92282 [cytosol] (Danio rerio)
Signaling by WNT (Danio rerio)
Beta-catenin independent WNT signaling (Danio rerio)
PCP/CE pathway (Danio rerio)
Asymmetric localization of PCP proteins (Danio rerio)
PRICKLE1 is degraded by the proteasome (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
zgc:92282 [cytosol] (Danio rerio)
TCF dependent signaling in response to WNT (Danio rerio)
Degradation of AXIN (Danio rerio)
Ubiquitinated AXIN is degraded by the proteasome (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
zgc:92282 [cytosol] (Danio rerio)
Degradation of DVL (Danio rerio)
Ubiquitinated DVL is degraded by the proteasome (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
zgc:92282 [cytosol] (Danio rerio)
Transport of small molecules (Danio rerio)
ABC-family proteins mediated transport (Danio rerio)
misfolded CFTR is degraded by the 26S proteasome (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
zgc:92282 [cytosol] (Danio rerio)
External Reference Information
External Reference
UniProt:Q6DHI9
Gene Names
zgc:92282
Reference Genes
BioGPS Gene:436882 zgc:92282
ENSEMBL:ENSDARG00000031511
ENSEMBL:ENSDARG00000031511.5 zgc:92282
KEGG Gene (Danio rerio):436882 zgc:92282
Monarch:436882 zgc:92282
NCBI Gene:436882 zgc:92282
Reference Transcript
RefSeq:NM_001002609.1 zgc:92282
Other Identifiers
13071507
436882
A_15_P103824
A_15_P106758
A_15_P521097
A_15_P675401
DRER04940
Dr.7341.1.A1_at
ENSDART00000041114
ENSDART00000041114_1
ENSDART00000041114_2
GO:0000502
GO:0005634
GO:0005737
GO:0005839
GO:0010498
GO:0019774
GO:0030163
GO:0043226
GO:0051603
GT_Spec_NM_001002609.1_239784
GT_Xhyb_XM_005170167.1_45701
MADDr01001911
NM_001002609
ZV700S00006095
Participates
as a component of
26S proteasome [cytosol] (Danio rerio)
Other forms of this molecule
zgc:92282 [nucleoplasm]
Inferred From
PSMB2 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001002609.1
ZFIN
ZDB-GENE-040718-353
Ensembl
ENSDARP00000041113
,
ENSDART00000041114
,
ENSDARG00000031511
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