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MCM4:MCM6:MCM7 [nucleoplasm]
Stable Identifier
R-DRE-69018
Type
Complex
Species
Danio rerio
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Cell Cycle (Danio rerio)
Cell Cycle, Mitotic (Danio rerio)
Mitotic G1 phase and G1/S transition (Danio rerio)
G1/S Transition (Danio rerio)
Activation of the pre-replicative complex (Danio rerio)
CDK and DDK associate with the Mcm10:pre-replicative complex (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM2-7 [nucleoplasm] (Danio rerio)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM2-7 [nucleoplasm] (Danio rerio)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
Cdc45 associates with the pre-replicative complex at the origin (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM2-7 [nucleoplasm] (Danio rerio)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM2-7 [nucleoplasm] (Danio rerio)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
Cdt1 is displaced from the pre-replicative complex (Danio rerio)
MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM2-7 [nucleoplasm] (Danio rerio)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM10:pre-replicative complex [nucleoplasm] (Danio rerio)
pre-replicative complex [nucleoplasm] (Danio rerio)
MCM2-7 [nucleoplasm] (Danio rerio)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM2-7 [nucleoplasm] (Danio rerio)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM2-7 [nucleoplasm] (Danio rerio)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
DNA polymerase alpha:primase binds at the origin (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM2-7 [nucleoplasm] (Danio rerio)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
DNA polymerase epsilon binds at the origin (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM2-7 [nucleoplasm] (Danio rerio)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 (Danio rerio)
MCM10:pre-replicative complex [nucleoplasm] (Danio rerio)
pre-replicative complex [nucleoplasm] (Danio rerio)
MCM2-7 [nucleoplasm] (Danio rerio)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
pre-replicative complex [nucleoplasm] (Danio rerio)
MCM2-7 [nucleoplasm] (Danio rerio)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
Mcm2-7 is phosphorylated by DDK (Danio rerio)
MCM2-7 [nucleoplasm] (Danio rerio)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
p-MCM2-7 [nucleoplasm] (Danio rerio)
MCM2-7 [nucleoplasm] (Danio rerio)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
S Phase (Danio rerio)
Synthesis of DNA (Danio rerio)
Switching of origins to a post-replicative state (Danio rerio)
Mcm4,6,7 trimer forms and associates with the replication fork (Danio rerio)
MCM2-7 [nucleoplasm] (Danio rerio)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
Orc1 removal from chromatin (Danio rerio)
Orc1 is phosphorylated by cyclin A/CDK2 (Danio rerio)
pre-replicative complex (Orc1-minus) [nucleoplasm] (Danio rerio)
MCM2-7 [nucleoplasm] (Danio rerio)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
pre-replicative complex [nucleoplasm] (Danio rerio)
MCM2-7 [nucleoplasm] (Danio rerio)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
DNA Replication (Danio rerio)
DNA Replication Pre-Initiation (Danio rerio)
Activation of the pre-replicative complex (Danio rerio)
CDK and DDK associate with the Mcm10:pre-replicative complex (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM2-7 [nucleoplasm] (Danio rerio)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM2-7 [nucleoplasm] (Danio rerio)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
Cdc45 associates with the pre-replicative complex at the origin (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM2-7 [nucleoplasm] (Danio rerio)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM2-7 [nucleoplasm] (Danio rerio)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
Cdt1 is displaced from the pre-replicative complex (Danio rerio)
MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM2-7 [nucleoplasm] (Danio rerio)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM10:pre-replicative complex [nucleoplasm] (Danio rerio)
pre-replicative complex [nucleoplasm] (Danio rerio)
MCM2-7 [nucleoplasm] (Danio rerio)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM2-7 [nucleoplasm] (Danio rerio)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM2-7 [nucleoplasm] (Danio rerio)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
DNA polymerase alpha:primase binds at the origin (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM2-7 [nucleoplasm] (Danio rerio)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
DNA polymerase epsilon binds at the origin (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM2-7 [nucleoplasm] (Danio rerio)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 (Danio rerio)
MCM10:pre-replicative complex [nucleoplasm] (Danio rerio)
pre-replicative complex [nucleoplasm] (Danio rerio)
MCM2-7 [nucleoplasm] (Danio rerio)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
pre-replicative complex [nucleoplasm] (Danio rerio)
MCM2-7 [nucleoplasm] (Danio rerio)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
Mcm2-7 is phosphorylated by DDK (Danio rerio)
MCM2-7 [nucleoplasm] (Danio rerio)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
p-MCM2-7 [nucleoplasm] (Danio rerio)
MCM2-7 [nucleoplasm] (Danio rerio)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
Assembly of the pre-replicative complex (Danio rerio)
Formation of MCM2-7 complex (Danio rerio)
MCM2-7 [nucleoplasm] (Danio rerio)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM2 binds MCM4:MCM6:MCM7 heterotrimer (Danio rerio)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4, MCM6 and MCM7 form a heterotrimer (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
Synthesis of DNA (Danio rerio)
Switching of origins to a post-replicative state (Danio rerio)
Mcm4,6,7 trimer forms and associates with the replication fork (Danio rerio)
MCM2-7 [nucleoplasm] (Danio rerio)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
Orc1 removal from chromatin (Danio rerio)
Orc1 is phosphorylated by cyclin A/CDK2 (Danio rerio)
pre-replicative complex (Orc1-minus) [nucleoplasm] (Danio rerio)
MCM2-7 [nucleoplasm] (Danio rerio)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
pre-replicative complex [nucleoplasm] (Danio rerio)
MCM2-7 [nucleoplasm] (Danio rerio)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
mcm4 [nucleoplasm]
(Danio rerio)
mcm6 [nucleoplasm]
(Danio rerio)
mcm7 [nucleoplasm]
(Danio rerio)
Participates
as an output of
Mcm4,6,7 trimer forms and associates with the replication fork (Danio rerio)
MCM4, MCM6 and MCM7 form a heterotrimer (Danio rerio)
as an input of
MCM2 binds MCM4:MCM6:MCM7 heterotrimer (Danio rerio)
as a component of
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Danio rerio)
Inferred From
MCM4:MCM6:MCM7 [nucleoplasm]
(Homo sapiens)
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