Reactome | rpl34 [cytosol]

rpl34 [cytosol]

Stable Identifier

R-DRE-72458

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

cytosol

Synonyms

RPL34, Q7ZWJ7

Locations in the PathwayBrowser

Expand all

Metabolism of RNA (Danio rerio)

- Nonsense-Mediated Decay (NMD) (Danio rerio)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Danio rerio)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Danio rerio)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Danio rerio)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Danio rerio)
        
        80S ribosome [cytosol] (Danio rerio)
        
        60S ribosomal complex [cytosol] (Danio rerio)
        
        rpl34 [cytosol] (Danio rerio)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Danio rerio)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Danio rerio)
        
        80S ribosome [cytosol] (Danio rerio)
        
        60S ribosomal complex [cytosol] (Danio rerio)
        
        rpl34 [cytosol] (Danio rerio)
    - SMG6 hydrolyzes mRNA with premature termination codon (Danio rerio)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Danio rerio)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Danio rerio)
        
        80S ribosome [cytosol] (Danio rerio)
        
        60S ribosomal complex [cytosol] (Danio rerio)
        
        rpl34 [cytosol] (Danio rerio)
    - p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Danio rerio)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Danio rerio)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Danio rerio)
        
        80S ribosome [cytosol] (Danio rerio)
        
        60S ribosomal complex [cytosol] (Danio rerio)
        
        rpl34 [cytosol] (Danio rerio)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Danio rerio)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Danio rerio)
        
        80S ribosome [cytosol] (Danio rerio)
        
        60S ribosomal complex [cytosol] (Danio rerio)
        
        rpl34 [cytosol] (Danio rerio)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Danio rerio)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Danio rerio)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Danio rerio)
        
        80S ribosome [cytosol] (Danio rerio)
        
        60S ribosomal complex [cytosol] (Danio rerio)
        
        rpl34 [cytosol] (Danio rerio)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Danio rerio)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Danio rerio)
        
        80S ribosome [cytosol] (Danio rerio)
        
        60S ribosomal complex [cytosol] (Danio rerio)
        
        rpl34 [cytosol] (Danio rerio)

External Reference Information

External Reference

UniProt:Q7ZWJ7

Gene Names

rpl34

Reference Genes

BioGPS Gene:394097 rpl34

ENSEMBL:ENSDARG00000029500

KEGG Gene (Danio rerio):394097 rpl34

Monarch:394097 rpl34

NCBI Gene:394097 rpl34

Reference Transcript

Other Identifiers

13232041

394097

BC062280

CUST_21863_PI428451953

DRER04903

DRER25243

DRER28954

DRER44693

Dr.15867.1.S1_at

ENSDART00000040771

ENSDART00000040771_1

ENSDART00000040771_2

GO:0003735

GO:0005198

GO:0005840

GO:0006412

GO:0043226

GT_Xhyb_XM_005166535.1_182855

LOLS11781

MADDr01008364

NM_201122

OTTDART00000025350

OTTDART00000025351

Participates

as a component of

Inferred From

RPL34 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_957416.1, XP_005166592.1

ZFIN

ZDB-GENE-040426-1033

Ensembl

ENSDART00000040771, ENSDARP00000108075, ENSDART00000181067, ENSDARP00000040770, ENSDART00000123520, ENSDARG00000029500, ENSDARP00000155419

PRO

Q7ZWJ7

PDB

7OYA, 7OYB

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