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rapgef1b [cytosol]
Stable Identifier
R-DRE-913472
Type
Protein [EntityWithAccessionedSequence]
Species
Danio rerio
Compartment
cytosol
Synonyms
RAPGEF1, E7F4B2
Locations in the PathwayBrowser
Expand all
Immune System (Danio rerio)
Cytokine Signaling in Immune system (Danio rerio)
Signaling by Interleukins (Danio rerio)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Danio rerio)
Regulation of signaling by CBL (Danio rerio)
CBL:CRKL binds RAPGEF1 (Danio rerio)
p(Y700,731,774)-CBL:CRK:RAPGEF1 [cytosol] (Danio rerio)
rapgef1b [cytosol] (Danio rerio)
rapgef1b [cytosol] (Danio rerio)
Signal Transduction (Danio rerio)
Signaling by Receptor Tyrosine Kinases (Danio rerio)
Signaling by MET (Danio rerio)
MET promotes cell motility (Danio rerio)
MET activates RAP1 and RAC1 (Danio rerio)
RAPGEF1 activates RAP1 (Danio rerio)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:RAPGEF1 [plasma membrane] (Danio rerio)
rapgef1b [cytosol] (Danio rerio)
rapgef1b [cytosol] (Danio rerio)
RAPGEF1 binds CRK,CRKL (Danio rerio)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:RAPGEF1 [plasma membrane] (Danio rerio)
rapgef1b [cytosol] (Danio rerio)
rapgef1b [cytosol] (Danio rerio)
Signaling by NTRKs (Danio rerio)
Signaling by NTRK1 (TRKA) (Danio rerio)
Signalling to ERKs (Danio rerio)
Prolonged ERK activation events (Danio rerio)
Frs2-mediated activation (Danio rerio)
p-FRS2:CRKL binds C3G (Danio rerio)
Active TrkA receptor:p-FRS2:CRKL:RAPGEF1 [endosome membrane] (Danio rerio)
rapgef1b [cytosol] (Danio rerio)
rapgef1b [cytosol] (Danio rerio)
Signaling by PDGF (Danio rerio)
Downstream signal transduction (Danio rerio)
p130Cas and C3G bind PDGFR bound Crk (Danio rerio)
PDGF:Phospho-PDGF receptor dimer:Crk:p130Cas:C3G [plasma membrane] (Danio rerio)
rapgef1b [cytosol] (Danio rerio)
rapgef1b [cytosol] (Danio rerio)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Danio rerio)
Signaling by Rho GTPases (Danio rerio)
RHO GTPase cycle (Danio rerio)
RAC3 GTPase cycle (Danio rerio)
RAC3 binds effectors at the plasma membrane (Danio rerio)
RAC3 effectors [cytosol] (Danio rerio)
rapgef1b [cytosol] (Danio rerio)
RAC3:GTP:RAC3 effectors [plasma membrane] (Danio rerio)
RAC3 effectors [cytosol] (Danio rerio)
rapgef1b [cytosol] (Danio rerio)
External Reference Information
External Reference
UniProt:E7F4B2
Gene Names
rapgef1b
Reference Genes
BioGPS Gene:394101 rapgef1b
CTD Gene:394101 rapgef1b
ENSEMBL:ENSDARG00000015971
KEGG Gene (Danio rerio):394101 rapgef1b
Monarch:394101 rapgef1b
NCBI Gene:394101 rapgef1b
Reference Transcript
RefSeq:NM_001328346.1 rapgef1b
Other Identifiers
13107505
13113284
13278868
394101
A_15_P194731
A_15_P445035
A_15_P676566
CUST_2892_PI428451953
DRER38721
DRER44837
Dr.24314.1.S1_at
ENSDART00000015576
ENSDART00000015576_2
ENSDART00000098624_1
ENSDART00000098624_2
GO:0003674
GO:0005085
GO:0007165
GO:0007264
GO:0008150
GO:0019899
LOLS02712
MADDr01001008
NM_201126
XM_683591
XM_685508
ZV700S00004150
Participates
as a component of
p-CRKL:RAPGEF1 [cytosol] (Danio rerio)
p(Y700,731,774)-CBL:CRK:RAPGEF1 [cytosol] (Danio rerio)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:RAPGEF1 [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer:Crk:p130Cas:C3G [plasma membrane] (Danio rerio)
Active TrkA receptor:p-FRS2:CRKL:RAPGEF1 [endosome membrane] (Danio rerio)
as a candidate of
RAC3 effectors [cytosol] (Danio rerio)
as an input of
CBL:CRKL binds RAPGEF1 (Danio rerio)
RAPGEF1 binds CRK,CRKL (Danio rerio)
p130Cas and C3G bind PDGFR bound Crk (Danio rerio)
p-FRS2:CRKL binds C3G (Danio rerio)
Inferred From
RAPGEF1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001315275.1
Ensembl
ENSDARP00000111128
,
ENSDARG00000015971
,
ENSDART00000123759
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