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PB1 [nucleoplasm]
Stable Identifier
R-FLU-188843
Type
Protein [EntityWithAccessionedSequence]
Species
Influenza A virus
Compartment
nucleoplasm
GO Cellular Component
host cell nucleoplasm
(0044095)
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Influenza Infection (Homo sapiens)
Influenza Life Cycle (Homo sapiens)
Export of Viral Ribonucleoproteins from Nucleus (Homo sapiens)
NEP/NS2 Interacts with the Cellular Export Machinery (Homo sapiens)
Binding of vRNP:M1:NEP complex to CRM1 export receptor (Homo sapiens)
vRNP Export Complex [nucleoplasm] (Homo sapiens)
vRNP:M1:NEP [nucleoplasm] (Influenza A virus)
vRNP:M1 for Export [nucleoplasm] (Influenza A virus)
vRNP destined for Export [nucleoplasm] (Influenza A virus)
PB1 [nucleoplasm] (Influenza A virus)
vRNP:M1:NEP [nucleoplasm] (Influenza A virus)
vRNP:M1 for Export [nucleoplasm] (Influenza A virus)
vRNP destined for Export [nucleoplasm] (Influenza A virus)
PB1 [nucleoplasm] (Influenza A virus)
vRNP Export through the nuclear pore (Homo sapiens)
vRNP Export Complex [nucleoplasm] (Homo sapiens)
vRNP:M1:NEP [nucleoplasm] (Influenza A virus)
vRNP:M1 for Export [nucleoplasm] (Influenza A virus)
vRNP destined for Export [nucleoplasm] (Influenza A virus)
PB1 [nucleoplasm] (Influenza A virus)
Viral RNP Complexes in the Host Cell Nucleus (Homo sapiens)
Binding of M1 to vRNP (Homo sapiens)
vRNP destined for Export [nucleoplasm] (Influenza A virus)
PB1 [nucleoplasm] (Influenza A virus)
vRNP:M1 for Export [nucleoplasm] (Influenza A virus)
vRNP destined for Export [nucleoplasm] (Influenza A virus)
PB1 [nucleoplasm] (Influenza A virus)
Binding of NEP/NS2 to vRNP:M1 (Homo sapiens)
vRNP:M1 for Export [nucleoplasm] (Influenza A virus)
vRNP destined for Export [nucleoplasm] (Influenza A virus)
PB1 [nucleoplasm] (Influenza A virus)
vRNP:M1:NEP [nucleoplasm] (Influenza A virus)
vRNP:M1 for Export [nucleoplasm] (Influenza A virus)
vRNP destined for Export [nucleoplasm] (Influenza A virus)
PB1 [nucleoplasm] (Influenza A virus)
Newly synthesized vRNP for export (Homo sapiens)
PB1 [nucleoplasm] (Influenza A virus)
vRNP destined for Export [nucleoplasm] (Influenza A virus)
PB1 [nucleoplasm] (Influenza A virus)
Influenza Viral RNA Transcription and Replication (Homo sapiens)
Viral Messenger RNA Synthesis (Homo sapiens)
Assembly of an Active Transcription Complex (Homo sapiens)
Viral Polymerase [nucleoplasm] (Influenza A virus)
PB1 [nucleoplasm] (Influenza A virus)
vRNA Transcription Complex [nucleoplasm] (Influenza A virus)
Viral Polymerase [nucleoplasm] (Influenza A virus)
PB1 [nucleoplasm] (Influenza A virus)
Elongation, Polyadenylation and Termination (Homo sapiens)
Initiated vRNA Transcription Complex [nucleoplasm] (Influenza A virus)
Viral Polymerase [nucleoplasm] (Influenza A virus)
PB1 [nucleoplasm] (Influenza A virus)
Viral Polymerase [nucleoplasm] (Influenza A virus)
PB1 [nucleoplasm] (Influenza A virus)
Priming and Initiation of Transcription (Homo sapiens)
Initiated vRNA Transcription Complex [nucleoplasm] (Influenza A virus)
Viral Polymerase [nucleoplasm] (Influenza A virus)
PB1 [nucleoplasm] (Influenza A virus)
Viral Polymerase [nucleoplasm] (Influenza A virus)
PB1 [nucleoplasm] (Influenza A virus)
vRNA Transcription Complex [nucleoplasm] (Influenza A virus)
Viral Polymerase [nucleoplasm] (Influenza A virus)
PB1 [nucleoplasm] (Influenza A virus)
cRNA Synthesis (Homo sapiens)
Initiation of cRNA Synthesis (Homo sapiens)
Initiated vRNA-cRNA Complex [nucleoplasm] (Influenza A virus)
Viral Polymerase [nucleoplasm] (Influenza A virus)
PB1 [nucleoplasm] (Influenza A virus)
Viral Polymerase [nucleoplasm] (Influenza A virus)
PB1 [nucleoplasm] (Influenza A virus)
cRNA Extension (Homo sapiens)
Initiated vRNA-cRNA Complex [nucleoplasm] (Influenza A virus)
Viral Polymerase [nucleoplasm] (Influenza A virus)
PB1 [nucleoplasm] (Influenza A virus)
Viral Polymerase [nucleoplasm] (Influenza A virus)
PB1 [nucleoplasm] (Influenza A virus)
vRNA Synthesis (Homo sapiens)
Initiation of vRNA Synthesis (Homo sapiens)
Initiated cRNA-vRNA Complex [nucleoplasm] (Influenza A virus)
Viral Polymerase [nucleoplasm] (Influenza A virus)
PB1 [nucleoplasm] (Influenza A virus)
Viral Polymerase [nucleoplasm] (Influenza A virus)
PB1 [nucleoplasm] (Influenza A virus)
vRNA Extension (Homo sapiens)
Initiated cRNA-vRNA Complex [nucleoplasm] (Influenza A virus)
Viral Polymerase [nucleoplasm] (Influenza A virus)
PB1 [nucleoplasm] (Influenza A virus)
Viral Polymerase [nucleoplasm] (Influenza A virus)
PB1 [nucleoplasm] (Influenza A virus)
vRNP Assembly (Homo sapiens)
Viral Polymerase Assembly (Homo sapiens)
PB1 [nucleoplasm] (Influenza A virus)
Viral Polymerase [nucleoplasm] (Influenza A virus)
PB1 [nucleoplasm] (Influenza A virus)
Transport of Ribonucleoproteins into the Host Nucleus (Homo sapiens)
Docking and transport of the RNP:Karyopherin complex through the nuclear pore (Homo sapiens)
RNP:Karyopherin alpha:Karyopherin beta complex [nucleoplasm] (Homo sapiens)
RNP Complex:Karyopherin alpha [nucleoplasm] (Homo sapiens)
Ribonucleoprotein (RNP) Complex [nucleoplasm] (Influenza A virus)
PB1 [nucleoplasm] (Influenza A virus)
Release of the RNP into the host cell nucleus (Homo sapiens)
RNP:Karyopherin alpha:Karyopherin beta complex [nucleoplasm] (Homo sapiens)
RNP Complex:Karyopherin alpha [nucleoplasm] (Homo sapiens)
Ribonucleoprotein (RNP) Complex [nucleoplasm] (Influenza A virus)
PB1 [nucleoplasm] (Influenza A virus)
Ribonucleoprotein (RNP) Complex [nucleoplasm] (Influenza A virus)
PB1 [nucleoplasm] (Influenza A virus)
External Reference Information
External Reference
UniProt:P03431 PB1
Gene Names
PB1
Chain
chain:1-757
Reference Genes
BioGPS Gene:956534 PB1
dbSNP Gene:956534 PB1
KEGG Gene (Viruses):956534 PB1
KEGG Gene (Viruses):956534 PB1
Monarch:956534 PB1
NCBI Gene:956534 PB1
Reference Transcript
RefSeq:NC_002021.1 PB1
Participant Of
input
Newly synthesized vRNP for export
Viral Polymerase Assembly
hasComponent
Ribonucleoprotein (RNP) Complex [nucleoplasm]
Viral Polymerase [nucleoplasm]
vRNP destined for Export [nucleoplasm]
Other forms of this molecule
PB1 [extracellular region]
PB1 [endosome lumen]
PB1 [cytosol]
Cross References
RefSeq
NP_040985.1
IntEnz
2.7.7.48
PRO
P03431
PDB
2ZNL
,
3A1G
,
2ZTT
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P03433 PA
4
PA [endosome lumen]
(R-FLU-189131)
PA [extracellular region]
(R-FLU-169243)
PA [cytosol]
(R-FLU-195948)
PA [nucleoplasm]
(R-FLU-188877)
0.819
6
UniProt:P03466 NP
6
NP [plasma membrane]
(R-FLU-195752)
NP [Golgi membrane]
(R-FLU-195740)
NP [extracellular region]
(R-FLU-169251)
NP [endosome lumen]
(R-FLU-189141)
NP [cytosol]
(R-FLU-188848)
NP [nucleoplasm]
(R-FLU-188832)
0.737
5
UniProt:P03428 PB2
5
PB2 [endosome lumen]
(R-FLU-189140)
PB2 [extracellular region]
(R-FLU-169238)
PB2 [cytosol]
(R-FLU-188851)
PB2 [cytosol]
(R-FLU-195946)
PB2 [nucleoplasm]
(R-FLU-188857)
0.632
3
UniProt:Q99959 PKP2
2
PKP2 [plasma membrane]
(R-HSA-6814393)
PKP2 [cornified envelope]
(R-HSA-8847734)
0.599
8
UniProt:Q14318 FKBP8
2
PolyUb-FKBP8 [mitochondrial outer membrane]
(R-HSA-6783001)
FKBP8 [mitochondrial outer membrane]
(R-HSA-5696928)
0.499
5
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