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phospho-Ub-K21,22-p-S32,S36-NFKBIA [cytosol]
Stable Identifier
R-GGA-1168581
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
R4GH80
Locations in the PathwayBrowser
Expand all
Immune System (Gallus gallus)
Adaptive Immune System (Gallus gallus)
Signaling by the B Cell Receptor (BCR) (Gallus gallus)
Downstream signaling events of B Cell Receptor (BCR) (Gallus gallus)
Activation of NF-kappaB in B cells (Gallus gallus)
SCF-beta-TrCP ubiquitinylates IkB (Gallus gallus)
NF-kappaB p50,p65,c-Rel:ub-p-IKB [cytosol] (Gallus gallus)
NF-KappaB p50:p50:ub-p-IKBA [cytosol] (Gallus gallus)
phospho-Ub-K21,22-p-S32,S36-NFKBIA [cytosol] (Gallus gallus)
NF-kappaB p50:c-Rel:ub-p-IKB [cytosol] (Gallus gallus)
ub-p-IKB alpha,beta,epsilon [cytosol] (Gallus gallus)
phospho-Ub-K21,22-p-S32,S36-NFKBIA [cytosol] (Gallus gallus)
NF-kappaB p50:p65:ub-p-IKB [cytosol] (Gallus gallus)
ub-p-IKB alpha,beta,epsilon [cytosol] (Gallus gallus)
phospho-Ub-K21,22-p-S32,S36-NFKBIA [cytosol] (Gallus gallus)
Ubiquitinated IkB is degraded (Gallus gallus)
NF-kappaB p50,p65,c-Rel:ub-p-IKB [cytosol] (Gallus gallus)
NF-KappaB p50:p50:ub-p-IKBA [cytosol] (Gallus gallus)
phospho-Ub-K21,22-p-S32,S36-NFKBIA [cytosol] (Gallus gallus)
NF-kappaB p50:c-Rel:ub-p-IKB [cytosol] (Gallus gallus)
ub-p-IKB alpha,beta,epsilon [cytosol] (Gallus gallus)
phospho-Ub-K21,22-p-S32,S36-NFKBIA [cytosol] (Gallus gallus)
NF-kappaB p50:p65:ub-p-IKB [cytosol] (Gallus gallus)
ub-p-IKB alpha,beta,epsilon [cytosol] (Gallus gallus)
phospho-Ub-K21,22-p-S32,S36-NFKBIA [cytosol] (Gallus gallus)
TCR signaling (Gallus gallus)
Downstream TCR signaling (Gallus gallus)
26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex (Gallus gallus)
K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex [cytosol] (Gallus gallus)
phospho-Ub-K21,22-p-S32,S36-NFKBIA [cytosol] (Gallus gallus)
beta-TRCP ubiquitinates IkB-alpha in p-S32,33-IkB-alpha:NF-kB complex (Gallus gallus)
K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex [cytosol] (Gallus gallus)
phospho-Ub-K21,22-p-S32,S36-NFKBIA [cytosol] (Gallus gallus)
Innate Immune System (Gallus gallus)
C-type lectin receptors (CLRs) (Gallus gallus)
CLEC7A (Dectin-1) signaling (Gallus gallus)
26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex (Gallus gallus)
K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex [cytosol] (Gallus gallus)
phospho-Ub-K21,22-p-S32,S36-NFKBIA [cytosol] (Gallus gallus)
beta-TRCP ubiquitinates IkB-alpha in p-S32,33-IkB-alpha:NF-kB complex (Gallus gallus)
K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex [cytosol] (Gallus gallus)
phospho-Ub-K21,22-p-S32,S36-NFKBIA [cytosol] (Gallus gallus)
Fc epsilon receptor (FCERI) signaling (Gallus gallus)
FCERI mediated NF-kB activation (Gallus gallus)
26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex (Gallus gallus)
K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex [cytosol] (Gallus gallus)
phospho-Ub-K21,22-p-S32,S36-NFKBIA [cytosol] (Gallus gallus)
beta-TRCP ubiquitinates IkB-alpha in p-S32,33-IkB-alpha:NF-kB complex (Gallus gallus)
K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex [cytosol] (Gallus gallus)
phospho-Ub-K21,22-p-S32,S36-NFKBIA [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:R4GH80
Reference Genes
ENSEMBL:ENSGALG00000027864
UCSC:R4GH80
Participates
as a component of
NF-KappaB p50:p50:ub-p-IKBA [cytosol] (Gallus gallus)
K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex [cytosol] (Gallus gallus)
as a member of
ub-p-IKB alpha,beta,epsilon [cytosol] (Gallus gallus)
Other forms of this molecule
monoSUMO1-K21-NFKBIA [nucleoplasm]
NFKBIA [nucleoplasm]
phospho-p-S32,S36-NFKBIA [cytosol]
NFKBIA [cytosol]
Inferred From
Ub-K21,22-p-S32,S36-NFKBIA [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 32 (in Homo sapiens)
Coordinate
32
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 36 (in Homo sapiens)
Coordinate
36
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
ubiquitinylated lysine (K48polyUb [cytosol]) at 21 (in Homo sapiens)
Coordinate
21
Modification
K48polyUb [cytosol]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Name
ubiquitinylated lysine (K48polyUb [cytosol]) at 22 (in Homo sapiens)
Coordinate
22
Modification
K48polyUb [cytosol]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
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