Reactome: A Curated Pathway Database

NLRX1 inhibits IPS1 signaling

Stable Identifier
R-GGA-1227698
Type
Reaction
Species
Gallus gallus
Compartment
Locations in the PathwayBrowser
Summation

NLRX1 is a member of nucleotide-binding domain and leucine-rich repeat containing (NLR) protein family. Upon viral stimulation mammalian NLRX1 competes with RIG-I for IPS-1 interaction and has been identified as a negative regulator of RLR signaling.

Literature References
PubMed ID Title Journal Year
Participants
Participant Of
Inferred From