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Caspase-8 dimer [cytosol]
Stable Identifier
R-GGA-139950
Type
Complex
Species
Gallus gallus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Immune System (Gallus gallus)
Cytokine Signaling in Immune system (Gallus gallus)
Signaling by Interleukins (Gallus gallus)
Interleukin-1 family signaling (Gallus gallus)
Interleukin-1 signaling (Gallus gallus)
TAK1-dependent IKK and NF-kappa-B activation (Gallus gallus)
Regulation of NF-kappa B signaling (Gallus gallus)
CASP8 cleaves N4BP1 at D424, D490 (Gallus gallus)
active caspase-8 [cytosol] (Gallus gallus)
Caspase-8 dimer [cytosol] (Gallus gallus)
Innate Immune System (Gallus gallus)
C-type lectin receptors (CLRs) (Gallus gallus)
CLEC7A (Dectin-1) signaling (Gallus gallus)
CLEC7A/inflammasome pathway (Gallus gallus)
Caspase-8 binds MALT (Gallus gallus)
MALT1:active caspase-8 [cytosol] (Gallus gallus)
active caspase-8 [cytosol] (Gallus gallus)
Caspase-8 dimer [cytosol] (Gallus gallus)
active caspase-8 [cytosol] (Gallus gallus)
Caspase-8 dimer [cytosol] (Gallus gallus)
Toll-like Receptor Cascades (Gallus gallus)
Toll Like Receptor 10 (TLR10) Cascade (Gallus gallus)
MyD88 cascade initiated on plasma membrane (Gallus gallus)
TAK1-dependent IKK and NF-kappa-B activation (Gallus gallus)
Regulation of NF-kappa B signaling (Gallus gallus)
CASP8 cleaves N4BP1 at D424, D490 (Gallus gallus)
active caspase-8 [cytosol] (Gallus gallus)
Caspase-8 dimer [cytosol] (Gallus gallus)
Toll Like Receptor 2 (TLR2) Cascade (Gallus gallus)
Toll Like Receptor TLR1:TLR2 Cascade (Gallus gallus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Gallus gallus)
TAK1-dependent IKK and NF-kappa-B activation (Gallus gallus)
Regulation of NF-kappa B signaling (Gallus gallus)
CASP8 cleaves N4BP1 at D424, D490 (Gallus gallus)
active caspase-8 [cytosol] (Gallus gallus)
Caspase-8 dimer [cytosol] (Gallus gallus)
Toll Like Receptor TLR6:TLR2 Cascade (Gallus gallus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Gallus gallus)
TAK1-dependent IKK and NF-kappa-B activation (Gallus gallus)
Regulation of NF-kappa B signaling (Gallus gallus)
CASP8 cleaves N4BP1 at D424, D490 (Gallus gallus)
active caspase-8 [cytosol] (Gallus gallus)
Caspase-8 dimer [cytosol] (Gallus gallus)
Toll Like Receptor 3 (TLR3) Cascade (Gallus gallus)
TAK1-dependent IKK and NF-kappa-B activation (Gallus gallus)
Regulation of NF-kappa B signaling (Gallus gallus)
CASP8 cleaves N4BP1 at D424, D490 (Gallus gallus)
active caspase-8 [cytosol] (Gallus gallus)
Caspase-8 dimer [cytosol] (Gallus gallus)
Toll Like Receptor 4 (TLR4) Cascade (Gallus gallus)
MyD88-independent TLR4 cascade (Gallus gallus)
TRIF (TICAM1)-mediated TLR4 signaling (Gallus gallus)
TAK1-dependent IKK and NF-kappa-B activation (Gallus gallus)
Regulation of NF-kappa B signaling (Gallus gallus)
CASP8 cleaves N4BP1 at D424, D490 (Gallus gallus)
active caspase-8 [cytosol] (Gallus gallus)
Caspase-8 dimer [cytosol] (Gallus gallus)
TRIF-mediated programmed cell death (Gallus gallus)
Caspase-8 processing within TLR4 complex (Gallus gallus)
active caspase-8 [cytosol] (Gallus gallus)
Caspase-8 dimer [cytosol] (Gallus gallus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Gallus gallus)
TAK1-dependent IKK and NF-kappa-B activation (Gallus gallus)
Regulation of NF-kappa B signaling (Gallus gallus)
CASP8 cleaves N4BP1 at D424, D490 (Gallus gallus)
active caspase-8 [cytosol] (Gallus gallus)
Caspase-8 dimer [cytosol] (Gallus gallus)
Toll Like Receptor 5 (TLR5) Cascade (Gallus gallus)
MyD88 cascade initiated on plasma membrane (Gallus gallus)
TAK1-dependent IKK and NF-kappa-B activation (Gallus gallus)
Regulation of NF-kappa B signaling (Gallus gallus)
CASP8 cleaves N4BP1 at D424, D490 (Gallus gallus)
active caspase-8 [cytosol] (Gallus gallus)
Caspase-8 dimer [cytosol] (Gallus gallus)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Gallus gallus)
MyD88 dependent cascade initiated on endosome (Gallus gallus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Gallus gallus)
TAK1-dependent IKK and NF-kappa-B activation (Gallus gallus)
Regulation of NF-kappa B signaling (Gallus gallus)
CASP8 cleaves N4BP1 at D424, D490 (Gallus gallus)
active caspase-8 [cytosol] (Gallus gallus)
Caspase-8 dimer [cytosol] (Gallus gallus)
Toll Like Receptor 9 (TLR9) Cascade (Gallus gallus)
MyD88 dependent cascade initiated on endosome (Gallus gallus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Gallus gallus)
TAK1-dependent IKK and NF-kappa-B activation (Gallus gallus)
Regulation of NF-kappa B signaling (Gallus gallus)
CASP8 cleaves N4BP1 at D424, D490 (Gallus gallus)
active caspase-8 [cytosol] (Gallus gallus)
Caspase-8 dimer [cytosol] (Gallus gallus)
Programmed Cell Death (Gallus gallus)
Apoptosis (Gallus gallus)
Apoptotic execution phase (Gallus gallus)
Apoptotic cleavage of cellular proteins (Gallus gallus)
Caspase-mediated cleavage of cytoskeletal proteins (Gallus gallus)
Caspase mediated cleavage of vimentin at IDVD (259) (Gallus gallus)
Caspase-8 dimer [cytosol] (Gallus gallus)
active caspase-8 [cytosol] (Gallus gallus)
Caspase-8 dimer [cytosol] (Gallus gallus)
Translocation of active caspase-8 to the mitochondrial membrane (Gallus gallus)
active caspase-8 [cytosol] (Gallus gallus)
Caspase-8 dimer [cytosol] (Gallus gallus)
Caspase activation via extrinsic apoptotic signalling pathway (Gallus gallus)
Caspase activation via Death Receptors in the presence of ligand (Gallus gallus)
Caspase-8 processing within TLR4 complex (Gallus gallus)
active caspase-8 [cytosol] (Gallus gallus)
Caspase-8 dimer [cytosol] (Gallus gallus)
Regulation by c-FLIP (Gallus gallus)
Caspase-8 and FLIP(L) processing at DISC (Gallus gallus)
Caspase-8 dimer [cytosol] (Gallus gallus)
active caspase-8 [cytosol] (Gallus gallus)
Caspase-8 dimer [cytosol] (Gallus gallus)
Intrinsic Pathway for Apoptosis (Gallus gallus)
Activation, myristolyation of BID and translocation to mitochondria (Gallus gallus)
Caspase-8 activates BID by cleavage (Gallus gallus)
Caspase-8 dimer [cytosol] (Gallus gallus)
active caspase-8 [cytosol] (Gallus gallus)
Caspase-8 dimer [cytosol] (Gallus gallus)
Regulated Necrosis (Gallus gallus)
RIPK1-mediated regulated necrosis (Gallus gallus)
Regulation of necroptotic cell death (Gallus gallus)
RIPK1 is cleaved by CASP8 (Gallus gallus)
Caspase-8 dimer [cytosol] (Gallus gallus)
active caspase-8 [cytosol] (Gallus gallus)
Caspase-8 dimer [cytosol] (Gallus gallus)
Signal Transduction (Gallus gallus)
Death Receptor Signaling (Gallus gallus)
TNF signaling (Gallus gallus)
Regulation of TNFR1 signaling (Gallus gallus)
RIPK1 is cleaved by CASP8 (Gallus gallus)
Caspase-8 dimer [cytosol] (Gallus gallus)
active caspase-8 [cytosol] (Gallus gallus)
Caspase-8 dimer [cytosol] (Gallus gallus)
TRAF1 is cleaved by caspases (Gallus gallus)
Caspase-8 dimer [cytosol] (Gallus gallus)
active caspase-8 [cytosol] (Gallus gallus)
Caspase-8 dimer [cytosol] (Gallus gallus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
CASP8(217-374) [cytosol]
(Gallus gallus)
CASP8(385-479) [cytosol]
(Gallus gallus)
Participates
as a component of
active caspase-8 [cytosol] (Gallus gallus)
Inferred From
Caspase-8 dimer [cytosol]
(Homo sapiens)
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