Reactome | Nuclear Pore Complex (NPC) [nuclear envelope]

Nuclear Pore Complex (NPC) [nuclear envelope]

Stable Identifier

R-GGA-157689

Type

Complex

Species

Gallus gallus

Compartment

nuclear envelope

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

x 8 AAAS [nuclear envelope] (Gallus gallus)
x 32 NDC1 [nuclear envelope] (Gallus gallus)
x 32 Nup107-160 complex [cytosol] (Gallus gallus)
x 8 NUP153 [nucleoplasm] (Gallus gallus)
x 16 NUP188 [nuclear envelope] (Gallus gallus)
x 16 NUP210 [nuclear envelope] (Gallus gallus)
x 8 NUP214 [cytosol] (Gallus gallus)
x 16 NUP42 [cytosol] (Gallus gallus)
x 32 NUP50 [nucleoplasm] (Gallus gallus)
x 32 Nup62 Complex [nuclear envelope] (Gallus gallus)
x 32 NUP88 [cytosol] (Gallus gallus)
x 32 Nup93 complex [nuclear envelope] (Gallus gallus)
x 8 NUP98 [nuclear envelope] (Gallus gallus)
x 16 POM121 [nuclear envelope] (Gallus gallus)
x 48 RAE1 [nuclear envelope] (Gallus gallus)
x 8 RANBP2 [cytosol] (Gallus gallus)
x 16 SEH1L-2 [nuclear envelope] (Gallus gallus)
x 16 TPR [nucleoplasm] (Gallus gallus)

Participates

as an output of

mRNP complex dissociates from cytosolic face of NPC (Gallus gallus)

as a component of

NPC:NXF1,2:NXT1:EJC:CBC:mRNA [nucleoplasm] (Gallus gallus)
NPC:NXF1:NXT1:EJC:CBC:mRNA [cytosol] (Gallus gallus)

as an input of

CDK1 phosphorylates NUP98 (Gallus gallus)

This entity regulates

Positively

snRNP nuclear import and release (Gallus gallus)
Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC (Gallus gallus)
Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC (Gallus gallus)
Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex (Gallus gallus)
Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC (Gallus gallus)
Docking of Mature Replication Dependent Histone mRNA with the NPC (Gallus gallus)
Release of the SLBP independent Histone mRNA from the NPC (Gallus gallus)
Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC (Gallus gallus)
Docking of Mature Histone mRNA complex:TAP at the NPC (Gallus gallus)
mRNP complex dissociates from cytosolic face of NPC (Gallus gallus)
Transport of the export-competent mRNP complex through the NPC (Gallus gallus)

Inferred From

Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)

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