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MYD88 [cytosol]
Stable Identifier
R-GGA-166059
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
MYD88, A5HNF6
Locations in the PathwayBrowser
Expand all
Immune System (Gallus gallus)
Cytokine Signaling in Immune system (Gallus gallus)
Signaling by Interleukins (Gallus gallus)
Interleukin-1 family signaling (Gallus gallus)
Interleukin-1 signaling (Gallus gallus)
IL1R1:IL1:IL1RAP binds MYD88 homodimer (Gallus gallus)
IL1R1:IL1:IL1RAP:MYD88 dimer [plasma membrane] (Gallus gallus)
MYD88 dimer [cytosol] (Gallus gallus)
MYD88 [cytosol] (Gallus gallus)
MYD88 dimer [cytosol] (Gallus gallus)
MYD88 [cytosol] (Gallus gallus)
IRAK2 is phosphorylated downstream of IRAK4 following IL1 receptor activation (Gallus gallus)
IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP [plasma membrane] (Gallus gallus)
MYD88 dimer [cytosol] (Gallus gallus)
MYD88 [cytosol] (Gallus gallus)
IRAK4 is activated by autophosphorylation (Gallus gallus)
IL1R1:IL1:IL1RAP:IRAK4:MYD88 dimer:TOLLIP [plasma membrane] (Gallus gallus)
IL1R1:IL1:IL1RAP:IRAK4:MYD88 dimer [plasma membrane] (Gallus gallus)
IL1R1:IL1:IL1RAP:MYD88 dimer [plasma membrane] (Gallus gallus)
MYD88 dimer [cytosol] (Gallus gallus)
MYD88 [cytosol] (Gallus gallus)
IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP [plasma membrane] (Gallus gallus)
MYD88 dimer [cytosol] (Gallus gallus)
MYD88 [cytosol] (Gallus gallus)
The Interleukin 1 receptor complex binds Tollip (Gallus gallus)
IL1R1:IL1:IL1RAP:IRAK4:MYD88 dimer [plasma membrane] (Gallus gallus)
IL1R1:IL1:IL1RAP:MYD88 dimer [plasma membrane] (Gallus gallus)
MYD88 dimer [cytosol] (Gallus gallus)
MYD88 [cytosol] (Gallus gallus)
IL1R1:IL1:IL1RAP:IRAK4:MYD88 dimer:TOLLIP [plasma membrane] (Gallus gallus)
IL1R1:IL1:IL1RAP:IRAK4:MYD88 dimer [plasma membrane] (Gallus gallus)
IL1R1:IL1:IL1RAP:MYD88 dimer [plasma membrane] (Gallus gallus)
MYD88 dimer [cytosol] (Gallus gallus)
MYD88 [cytosol] (Gallus gallus)
Innate Immune System (Gallus gallus)
Cytosolic sensors of pathogen-associated DNA (Gallus gallus)
DEx/H-box helicases activate type I IFN and inflammatory cytokines production (Gallus gallus)
DHX36 or DHX9 binds MyD88 (Gallus gallus)
DHX36:CpG:MyD88 [cytosol] (Gallus gallus)
MYD88 [cytosol] (Gallus gallus)
MYD88 [cytosol] (Gallus gallus)
p-IRF7:p-IRF7 translocates to the nucleus (Gallus gallus)
DHX36:CpG:MyD88 [cytosol] (Gallus gallus)
MYD88 [cytosol] (Gallus gallus)
Signal Transduction (Gallus gallus)
Death Receptor Signaling (Gallus gallus)
p75 NTR receptor-mediated signalling (Gallus gallus)
p75NTR signals via NF-kB (Gallus gallus)
p75NTR recruits signalling complexes (Gallus gallus)
IRAK interacts with TRAF6 (Gallus gallus)
NGF ligand:p75NTR:Phospho-IRAK1:MYD88:TRAF6 [plasma membrane] (Gallus gallus)
NGF ligand:p75NTR:p-IRAK1:MYD88 [plasma membrane] (Gallus gallus)
MYD88 dimer [cytosol] (Gallus gallus)
MYD88 [cytosol] (Gallus gallus)
NGF ligand:p75NTR:p-IRAK1:MYD88 [plasma membrane] (Gallus gallus)
MYD88 dimer [cytosol] (Gallus gallus)
MYD88 [cytosol] (Gallus gallus)
MYD88 dissociates (Gallus gallus)
MYD88 dimer [cytosol] (Gallus gallus)
MYD88 [cytosol] (Gallus gallus)
NGF ligand:p75NTR:Phospho-IRAK1:MYD88:TRAF6 [plasma membrane] (Gallus gallus)
NGF ligand:p75NTR:p-IRAK1:MYD88 [plasma membrane] (Gallus gallus)
MYD88 dimer [cytosol] (Gallus gallus)
MYD88 [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:A5HNF6 MYD88
Gene Names
MYD88, RCJMB04_14h3
Chain
chain:1-299
Reference Genes
BioGPS Gene:420420 MYD88
ENSEMBL:ENSGALG00000005947 MYD88
KEGG Gene (Gallus gallus):420420 MYD88
Monarch:420420 MYD88
NCBI Gene:420420 MYD88
Reference Transcript
RefSeq:NM_001030962.3 MYD88
Participates
as an input of
DHX36 or DHX9 binds MyD88 (Gallus gallus)
as a component of
DHX36:CpG:MyD88 [cytosol] (Gallus gallus)
MYD88 dimer [cytosol] (Gallus gallus)
Other forms of this molecule
MyD88 [endosome membrane]
MyD88 [cytosol]
MyD88 [plasma membrane]
Inferred From
MYD88 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001026133.2
OpenTargets
ENSG00000172936
PRO
A5HNF6
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