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phospho-p-4Y-PLCG1 [plasma membrane]
Stable Identifier
R-GGA-167679
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
plasma membrane
Synonyms
F1NN68
Locations in the PathwayBrowser
Expand all
Immune System (Gallus gallus)
Adaptive Immune System (Gallus gallus)
TCR signaling (Gallus gallus)
Generation of second messenger molecules (Gallus gallus)
PLC-gamma1 hydrolyses PIP2 (Gallus gallus)
p-PLCG [plasma membrane] (Gallus gallus)
phospho-p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
phospho-p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
Translocation of PLC-gamma1 to PIP2 (Gallus gallus)
Activated PLC gamma1 bound to PIP2 [plasma membrane] (Gallus gallus)
phospho-p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
Innate Immune System (Gallus gallus)
DAP12 interactions (Gallus gallus)
DAP12 signaling (Gallus gallus)
Phosphorylation of PLC-gamma by p-BTK/p-SYK (Gallus gallus)
p-5Y-LAT:GRB2:SOS:GADS:p-3Y-SLP-76:p-2Y-BTK:VAV:p-PLCG [plasma membrane] (Gallus gallus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:p-PLCG [plasma membrane] (Gallus gallus)
p-4Y-PLCG [plasma membrane] (Gallus gallus)
phospho-p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
Release of p-PLCG1 (Gallus gallus)
p-4Y-PLCG [plasma membrane] (Gallus gallus)
phospho-p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
p-5Y-LAT:GRB2:SOS:GADS:p-3Y-SLP-76:p-2Y-BTK:VAV:p-PLCG [plasma membrane] (Gallus gallus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:p-PLCG [plasma membrane] (Gallus gallus)
p-4Y-PLCG [plasma membrane] (Gallus gallus)
phospho-p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
Fc epsilon receptor (FCERI) signaling (Gallus gallus)
FCERI mediated Ca+2 mobilization (Gallus gallus)
Hydrolysis of PIP2 by PLCG (Gallus gallus)
p-4Y-PLCG [plasma membrane] (Gallus gallus)
phospho-p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-2Y-BTK/p-2Y-ITK:PIP3 [plasma membrane] (Gallus gallus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:p-PLCG [plasma membrane] (Gallus gallus)
p-4Y-PLCG [plasma membrane] (Gallus gallus)
phospho-p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
Fcgamma receptor (FCGR) dependent phagocytosis (Gallus gallus)
Role of phospholipids in phagocytosis (Gallus gallus)
Phosphorylation and activation of PLCG (Gallus gallus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:p-3Y-PLCG [plasma membrane] (Gallus gallus)
p-PLCG [plasma membrane] (Gallus gallus)
phospho-p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
Release of PLCG from FCGR (Gallus gallus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:p-3Y-PLCG [plasma membrane] (Gallus gallus)
p-PLCG [plasma membrane] (Gallus gallus)
phospho-p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
p-PLCG [plasma membrane] (Gallus gallus)
phospho-p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
Signal Transduction (Gallus gallus)
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by ALK (Gallus gallus)
Active ALK phosphorylates PLCG1 (Gallus gallus)
Active ALK:p-4Y PLCG1 [plasma membrane] (Gallus gallus)
phospho-p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
Signaling by EGFR (Gallus gallus)
EGFR interacts with phospholipase C-gamma (Gallus gallus)
Active PLC-gamma1 dissociates from EGFR (Gallus gallus)
EGF-like ligand:p-6Y-EGFR:p-Y472,771,783,1254-PLCG1 [plasma membrane] (Gallus gallus)
phospho-p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
phospho-p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
EGFR activates PLC-gamma1 by phosphorylation (Gallus gallus)
EGF-like ligand:p-6Y-EGFR:p-Y472,771,783,1254-PLCG1 [plasma membrane] (Gallus gallus)
phospho-p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
Signaling by FGFR (Gallus gallus)
Signaling by FGFR1 (Gallus gallus)
Downstream signaling of activated FGFR1 (Gallus gallus)
Phospholipase C-mediated cascade: FGFR1 (Gallus gallus)
Activated FGFR1 phosphorylates PLCG1 (Gallus gallus)
activated FGFR1:p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
phospho-p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
p-4Y-PLCG1 dissociates from activated FGFR1 (Gallus gallus)
activated FGFR1:p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
phospho-p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
phospho-p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
Signaling by FGFR2 (Gallus gallus)
Downstream signaling of activated FGFR2 (Gallus gallus)
Phospholipase C-mediated cascade; FGFR2 (Gallus gallus)
Activated FGFR2 phosphorylates PLCG1 (Gallus gallus)
activated FGFR2:p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
phospho-p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
p-4Y-PLCG1 dissociates from activated FGFR2 (Gallus gallus)
activated FGFR2:p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
phospho-p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
phospho-p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
Signaling by FGFR3 (Gallus gallus)
Downstream signaling of activated FGFR3 (Gallus gallus)
Phospholipase C-mediated cascade; FGFR3 (Gallus gallus)
Activated FGFR3 phosphorylates PLCG1 (Gallus gallus)
activated FGFR3:p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
phospho-p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
p-4Y-PLCG1 dissociates from activated FGFR3 (Gallus gallus)
activated FGFR3:p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
phospho-p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
phospho-p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
Signaling by FGFR4 (Gallus gallus)
Downstream signaling of activated FGFR4 (Gallus gallus)
Phospholipase C-mediated cascade; FGFR4 (Gallus gallus)
Activated FGFR4 phosphorylates PLCG1 (Gallus gallus)
activated FGFR4:p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
phospho-p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
p-4Y-PLCG1 dissociates from activated FGFR4 (Gallus gallus)
activated FGFR4:p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
phospho-p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
phospho-p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
Signaling by NTRKs (Gallus gallus)
Signaling by NTRK2 (TRKB) (Gallus gallus)
Activated NTRK2 signals through PLCG1 (Gallus gallus)
Activated PCLG1 dissociates from NTRK2 (Gallus gallus)
BDNF,NTF4:p-5Y-NTRK2:p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
phospho-p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
phospho-p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
Signaling by NTRK3 (TRKC) (Gallus gallus)
Activated NTRK3 signals through PLCG1 (Gallus gallus)
Activated PCLG1 dissociates from NTRK3 (Gallus gallus)
NTF3:p-5Y-NTRK3 homodimer:p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
phospho-p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
phospho-p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
Signaling by PDGF (Gallus gallus)
Downstream signal transduction (Gallus gallus)
Activated PLC gamma dissociates from the PDGF receptor (Gallus gallus)
PDGF:p-PDGFR dimer:p-PLCgamma [plasma membrane] (Gallus gallus)
phospho-p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
phospho-p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
Phosphorylation of PLCgamma by PDGFR (Gallus gallus)
PDGF:p-PDGFR dimer:p-PLCgamma [plasma membrane] (Gallus gallus)
phospho-p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
Signaling by VEGF (Gallus gallus)
VEGFA-VEGFR2 Pathway (Gallus gallus)
VEGFR2 mediated cell proliferation (Gallus gallus)
PLCG1 disassociates from VEGFR2 and translocate to PM (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
phospho-p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
phospho-p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
SFKs phosphorylate PLCG1 (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
phospho-p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
External Reference Information
External Reference
UniProt:F1NN68
Reference Genes
ENSEMBL:ENSGALG00000003750
Participates
as a component of
Active ALK:p-4Y PLCG1 [plasma membrane] (Gallus gallus)
BDNF,NTF4:p-5Y-NTRK2:p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
NTF3:p-5Y-NTRK3 homodimer:p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
PDGF:p-PDGFR dimer:p-PLCgamma [plasma membrane] (Gallus gallus)
Activated PLC gamma1 bound to PIP2 [plasma membrane] (Gallus gallus)
activated FGFR4:p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
activated FGFR2:p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
EGF-like ligand:p-6Y-EGFR:p-Y472,771,783,1254-PLCG1 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
activated FGFR1:p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
activated FGFR3:p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
as an output of
Activated PCLG1 dissociates from NTRK2 (Gallus gallus)
Activated PCLG1 dissociates from NTRK3 (Gallus gallus)
Activated PLC gamma dissociates from the PDGF receptor (Gallus gallus)
p-4Y-PLCG1 dissociates from activated FGFR4 (Gallus gallus)
p-4Y-PLCG1 dissociates from activated FGFR2 (Gallus gallus)
Active PLC-gamma1 dissociates from EGFR (Gallus gallus)
PLCG1 disassociates from VEGFR2 and translocate to PM (Gallus gallus)
p-4Y-PLCG1 dissociates from activated FGFR1 (Gallus gallus)
p-4Y-PLCG1 dissociates from activated FGFR3 (Gallus gallus)
as a member of
p-4Y-PLCG [plasma membrane] (Gallus gallus)
p-PLCG [plasma membrane] (Gallus gallus)
Other forms of this molecule
phospho-p-Y771,Y783-PLCG1 [plasma membrane]
phospho-p-Y771,Y783,Y1254-PLCG1 [cytosol]
PLCG1 [cytosol]
PLCG1 [plasma membrane]
Inferred From
p-4Y-PLCG1 [plasma membrane]
(Homo sapiens)
Modified Residues
Name
O4'-phospho-L-tyrosine at 472 (in Homo sapiens)
Coordinate
472
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 771 (in Homo sapiens)
Coordinate
771
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 783 (in Homo sapiens)
Coordinate
783
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1253 (in Homo sapiens)
Coordinate
1253
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
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