Reactome | NFKB1 [cytosol]

NFKB1 [cytosol]

Stable Identifier

R-GGA-168168

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

cytosol

Synonyms

NFKB1(1-433), Q04861

Locations in the PathwayBrowser

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Immune System (Gallus gallus)

- Adaptive Immune System (Gallus gallus)
  - Signaling by the B Cell Receptor (BCR) (Gallus gallus)
    - Downstream signaling events of B Cell Receptor (BCR) (Gallus gallus)
      - Activation of NF-kappaB in B cells (Gallus gallus)
        
        NF-kappaB translocates from the cytosol to the nucleus (Gallus gallus)
        
        NF-kappaB p50,p65,c-Rel dimer [cytosol] (Gallus gallus)
        
        NF-kappaB p50:c-Rel [cytosol] (Gallus gallus)
        
        NFKB1 [cytosol] (Gallus gallus)
        
        NF-kappaB p50:p50 [cytosol] (Gallus gallus)
        
        NFKB1 [cytosol] (Gallus gallus)
        
        SCF with beta-TrCP1 or beta-TrCP2 binds NF-kappaB:phospho-IkB (Gallus gallus)
        
        NF-kappa-B p50,p65,c-Rel:p-IKB [cytosol] (Gallus gallus)
        
        NF-KappaB p50:p50:p-IKBA [cytosol] (Gallus gallus)
        
        NF-kappaB p50:p50 [cytosol] (Gallus gallus)
        
        NFKB1 [cytosol] (Gallus gallus)
        
        NF-kappaB p50:c-Rel:p-IKB [cytosol] (Gallus gallus)
        
        NF-kappaB p50:c-Rel [cytosol] (Gallus gallus)
        
        NFKB1 [cytosol] (Gallus gallus)
        
        NF-kappaB:p-IkB:SCF-betaTrCP [cytosol] (Gallus gallus)
        
        NF-kappa-B p50,p65,c-Rel:p-IKB [cytosol] (Gallus gallus)
        
        NF-KappaB p50:p50:p-IKBA [cytosol] (Gallus gallus)
        
        NF-kappaB p50:p50 [cytosol] (Gallus gallus)
        
        NFKB1 [cytosol] (Gallus gallus)
        
        NF-kappaB p50:c-Rel:p-IKB [cytosol] (Gallus gallus)
        
        NF-kappaB p50:c-Rel [cytosol] (Gallus gallus)
        
        NFKB1 [cytosol] (Gallus gallus)
        
        SCF-beta-TrCP ubiquitinylates IkB (Gallus gallus)
        
        NF-kappaB p50,p65,c-Rel:ub-p-IKB [cytosol] (Gallus gallus)
        
        NF-KappaB p50:p50:ub-p-IKBA [cytosol] (Gallus gallus)
        
        NF-kappaB p50:p50 [cytosol] (Gallus gallus)
        
        NFKB1 [cytosol] (Gallus gallus)
        
        NF-kappaB p50:c-Rel:ub-p-IKB [cytosol] (Gallus gallus)
        
        NF-kappaB p50:c-Rel [cytosol] (Gallus gallus)
        
        NFKB1 [cytosol] (Gallus gallus)
        
        NF-kappaB:p-IkB:SCF-betaTrCP [cytosol] (Gallus gallus)
        
        NF-kappa-B p50,p65,c-Rel:p-IKB [cytosol] (Gallus gallus)
        
        NF-KappaB p50:p50:p-IKBA [cytosol] (Gallus gallus)
        
        NF-kappaB p50:p50 [cytosol] (Gallus gallus)
        
        NFKB1 [cytosol] (Gallus gallus)
        
        NF-kappaB p50:c-Rel:p-IKB [cytosol] (Gallus gallus)
        
        NF-kappaB p50:c-Rel [cytosol] (Gallus gallus)
        
        NFKB1 [cytosol] (Gallus gallus)

External Reference Information

External Reference

UniProt:Q04861 NFKB1

Gene Names

NFKB1

Chain

chain:1-983, chain:1-

Reference Genes

BioGPS Gene:396033 NFKB1

ENSEMBL:ENSGALG00000012304 NFKB1

KEGG Gene (Gallus gallus):396033 NFKB1

Monarch:396033 NFKB1

NCBI Gene:396033 NFKB1

Reference Transcript

Other Identifiers

396033

GO:0000122

GO:0000976

GO:0000977

GO:0000978

GO:0001227

GO:0001228

GO:0001818

GO:0003674

GO:0003677

GO:0003682

GO:0003700

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005737

GO:0005739

GO:0005829

GO:0005975

GO:0006355

GO:0006357

GO:0006629

GO:0006950

GO:0007165

GO:0007267

GO:0008092

GO:0008134

GO:0008150

GO:0009058

GO:0010629

GO:0010956

GO:0032695

GO:0034641

GO:0035994

GO:0042025

GO:0042802

GO:0042805

GO:0043226

GO:0043565

GO:0044281

GO:0045892

GO:0045893

GO:0045944

GO:0050728

GO:0051059

GO:0071222

GO:0071260

GO:0071316

GO:0071347

GO:0071354

GO:0071356

GO:0071359

GO:0090263

GO:1900127

GO:1904385

GO:2000630

GT_A_87_P058756

GT_A_87_P191953

Gga.4408.2.S1_a_at

Participant Of

hasComponent

Other forms of this molecule

NFKB1 [secretory granule lumen]

NFKB1 [extracellular region]

NFKB1 [specific granule lumen]

NFkB1_p50 [nucleoplasm]

NFkB1_p50 [cytosol]

NFKB1 [nucleoplasm]

NFKB1 [cytosol]

phospho-NFKB1 [cytosol]

Inferred From

NFKB1(1-433) [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_990465.1, XP_015140901.1

OpenTargets

ENSG00000109320

Ensembl

ENSGALT00000086369, ENSGALG00000012304, ENSGALT00000037607, ENSGALP00000036814, ENSGALP00000060090

PRO

Q04861