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MAP3K14 [cytosol]
Stable Identifier
R-GGA-168189
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
F1NMZ5
Locations in the PathwayBrowser
Expand all
Immune System (Gallus gallus)
Adaptive Immune System (Gallus gallus)
Costimulation by the CD28 family (Gallus gallus)
CD28 co-stimulation (Gallus gallus)
CD28 dependent PI3K/Akt signaling (Gallus gallus)
p-S400-Cot phosphorylates NIK (Gallus gallus)
MAP3K14 [cytosol] (Gallus gallus)
Cytokine Signaling in Immune system (Gallus gallus)
TNFR2 non-canonical NF-kB pathway (Gallus gallus)
K63polyUb-cIAP1,2 ubiquitinates TRAF3 (Gallus gallus)
TNFSF:TNFRSF heterotrimer:K63polyUb-cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Gallus gallus)
TRAF3:NIK [cytosol] (Gallus gallus)
MAP3K14 [cytosol] (Gallus gallus)
TNFSF:TNFRSF heterotrimer:TRAF2:K63polyUb-cIAP1,2:K48polyUb-TRAF3:NIK [plasma membrane] (Gallus gallus)
K48polyUb-TRAF3:NIK [cytosol] (Gallus gallus)
MAP3K14 [cytosol] (Gallus gallus)
NIK-->noncanonical NF-kB signaling (Gallus gallus)
Activation of NIK (Gallus gallus)
MAP3K14 [cytosol] (Gallus gallus)
Active NIK phosphorylates IKKA dimer (Gallus gallus)
Active NIK:p-S176,180-IKKA dimer [cytosol] (Gallus gallus)
MAP3K14 [cytosol] (Gallus gallus)
MAP3K14 [cytosol] (Gallus gallus)
Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Gallus gallus)
Active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB [cytosol] (Gallus gallus)
Active NIK:p-S176,180-IKKA dimer [cytosol] (Gallus gallus)
MAP3K14 [cytosol] (Gallus gallus)
Active NIK:p-S176,180-IKKA dimer:p100:RELB [cytosol] (Gallus gallus)
Active NIK:p-S176,180-IKKA dimer [cytosol] (Gallus gallus)
MAP3K14 [cytosol] (Gallus gallus)
NIK autophosphorylates on T559 (Gallus gallus)
MAP3K14 [cytosol] (Gallus gallus)
SCF-beta-TRCP binds p-7S-p100 in active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB (Gallus gallus)
Active NIK:p-176,S180-IKKA dimer:p-7S-p100:SCF-beta-TRCP [cytosol] (Gallus gallus)
Active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB [cytosol] (Gallus gallus)
Active NIK:p-S176,180-IKKA dimer [cytosol] (Gallus gallus)
MAP3K14 [cytosol] (Gallus gallus)
Active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB [cytosol] (Gallus gallus)
Active NIK:p-S176,180-IKKA dimer [cytosol] (Gallus gallus)
MAP3K14 [cytosol] (Gallus gallus)
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway (Gallus gallus)
TRAF2:TRAF1:cIAP1,2:TRAF3:NIK regulatory complex binds CD40 (Gallus gallus)
CD40:CD40L trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Gallus gallus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Gallus gallus)
TRAF3:NIK [cytosol] (Gallus gallus)
MAP3K14 [cytosol] (Gallus gallus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Gallus gallus)
TRAF3:NIK [cytosol] (Gallus gallus)
MAP3K14 [cytosol] (Gallus gallus)
TRAF3 binds BAFFR:BAFF (Gallus gallus)
3xBAFFR:BAFF trimer:TRAF3:NIK [plasma membrane] (Gallus gallus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Gallus gallus)
TRAF3:NIK [cytosol] (Gallus gallus)
MAP3K14 [cytosol] (Gallus gallus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Gallus gallus)
TRAF3:NIK [cytosol] (Gallus gallus)
MAP3K14 [cytosol] (Gallus gallus)
TRAFs bind RANK:RANKL (Gallus gallus)
3xRANK:RANKL,sRANKL trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Gallus gallus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Gallus gallus)
TRAF3:NIK [cytosol] (Gallus gallus)
MAP3K14 [cytosol] (Gallus gallus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Gallus gallus)
TRAF3:NIK [cytosol] (Gallus gallus)
MAP3K14 [cytosol] (Gallus gallus)
TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK (Gallus gallus)
Non-canonical NF-kB initiating TNFRSF memebers [plasma membrane] (Gallus gallus)
3xBAFFR:BAFF trimer:TRAF3:NIK [plasma membrane] (Gallus gallus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Gallus gallus)
TRAF3:NIK [cytosol] (Gallus gallus)
MAP3K14 [cytosol] (Gallus gallus)
3xRANK:RANKL,sRANKL trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Gallus gallus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Gallus gallus)
TRAF3:NIK [cytosol] (Gallus gallus)
MAP3K14 [cytosol] (Gallus gallus)
CD40:CD40L trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Gallus gallus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Gallus gallus)
TRAF3:NIK [cytosol] (Gallus gallus)
MAP3K14 [cytosol] (Gallus gallus)
TNFA:TNFR2 heterotrimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Gallus gallus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Gallus gallus)
TRAF3:NIK [cytosol] (Gallus gallus)
MAP3K14 [cytosol] (Gallus gallus)
TNFSF:TNFRSF heterotrimer:K63polyUb-cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Gallus gallus)
TRAF3:NIK [cytosol] (Gallus gallus)
MAP3K14 [cytosol] (Gallus gallus)
TRAF3:NIK binds TRAF2:cIAP1/2 (Gallus gallus)
TRAF3:NIK [cytosol] (Gallus gallus)
MAP3K14 [cytosol] (Gallus gallus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Gallus gallus)
TRAF3:NIK [cytosol] (Gallus gallus)
MAP3K14 [cytosol] (Gallus gallus)
cIAP1,2 ubiquitinates NIK in cIAP1,2:TRAF2::TRAF3:NIK (Gallus gallus)
TNFSF:TNFRSF heterotrimer:K63polyUb-cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Gallus gallus)
TRAF3:NIK [cytosol] (Gallus gallus)
MAP3K14 [cytosol] (Gallus gallus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Gallus gallus)
TRAF3:NIK [cytosol] (Gallus gallus)
MAP3K14 [cytosol] (Gallus gallus)
Innate Immune System (Gallus gallus)
C-type lectin receptors (CLRs) (Gallus gallus)
CLEC7A (Dectin-1) signaling (Gallus gallus)
Dectin-1 mediated noncanonical NF-kB signaling (Gallus gallus)
Activation of NIK (Gallus gallus)
MAP3K14 [cytosol] (Gallus gallus)
Active NIK phosphorylates IKKA dimer (Gallus gallus)
Active NIK:p-S176,180-IKKA dimer [cytosol] (Gallus gallus)
MAP3K14 [cytosol] (Gallus gallus)
MAP3K14 [cytosol] (Gallus gallus)
Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Gallus gallus)
Active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB [cytosol] (Gallus gallus)
Active NIK:p-S176,180-IKKA dimer [cytosol] (Gallus gallus)
MAP3K14 [cytosol] (Gallus gallus)
Active NIK:p-S176,180-IKKA dimer:p100:RELB [cytosol] (Gallus gallus)
Active NIK:p-S176,180-IKKA dimer [cytosol] (Gallus gallus)
MAP3K14 [cytosol] (Gallus gallus)
SCF-beta-TRCP binds p-7S-p100 in active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB (Gallus gallus)
Active NIK:p-176,S180-IKKA dimer:p-7S-p100:SCF-beta-TRCP [cytosol] (Gallus gallus)
Active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB [cytosol] (Gallus gallus)
Active NIK:p-S176,180-IKKA dimer [cytosol] (Gallus gallus)
MAP3K14 [cytosol] (Gallus gallus)
Active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB [cytosol] (Gallus gallus)
Active NIK:p-S176,180-IKKA dimer [cytosol] (Gallus gallus)
MAP3K14 [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:F1NMZ5
Reference Genes
ENSEMBL:ENSGALG00000000685
Participates
as an input of
NIK autophosphorylates on T559 (Gallus gallus)
p-S400-Cot phosphorylates NIK (Gallus gallus)
Activation of NIK (Gallus gallus)
Active NIK phosphorylates IKKA dimer (Gallus gallus)
as a component of
TRAF3:NIK [cytosol] (Gallus gallus)
K48polyUb-TRAF3:NIK [cytosol] (Gallus gallus)
Active NIK:p-S176,180-IKKA dimer [cytosol] (Gallus gallus)
as an output of
Activation of NIK (Gallus gallus)
Other forms of this molecule
phospho-p-T559-MAP3K14 [cytosol]
K48polyUb-NIK [cytosol]
phospho-p-MAP3K14 [cytosol]
Inferred From
MAP3K14 [cytosol]
(Homo sapiens)
Active NIK [cytosol]
(Homo sapiens)
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