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HUS1 [nucleoplasm]
Stable Identifier
R-GGA-176374
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
nucleoplasm
Synonyms
HUS1, A0A1D5PTJ5
Locations in the PathwayBrowser
Expand all
Cell Cycle (Gallus gallus)
Cell Cycle Checkpoints (Gallus gallus)
G2/M Checkpoints (Gallus gallus)
Activation of ATR in response to replication stress (Gallus gallus)
Recruitment of the Rad9-Hus1-Rad1 complex to DNA (Gallus gallus)
RAD9:HUS1:RAD1 [nucleoplasm] (Gallus gallus)
HUS1 [nucleoplasm] (Gallus gallus)
Rad9-Hus1-Rad1 bound to DNA [nucleoplasm] (Gallus gallus)
RAD9:HUS1:RAD1 [nucleoplasm] (Gallus gallus)
HUS1 [nucleoplasm] (Gallus gallus)
DNA Repair (Gallus gallus)
DNA Double-Strand Break Repair (Gallus gallus)
Homology Directed Repair (Gallus gallus)
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Gallus gallus)
HDR through Single Strand Annealing (SSA) (Gallus gallus)
Association of RAD51 with RAD52:DNA double-strand break ends (Gallus gallus)
RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Gallus gallus)
p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Gallus gallus)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Gallus gallus)
RAD9:HUS1:RAD1 [nucleoplasm] (Gallus gallus)
HUS1 [nucleoplasm] (Gallus gallus)
p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Gallus gallus)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Gallus gallus)
RAD9:HUS1:RAD1 [nucleoplasm] (Gallus gallus)
HUS1 [nucleoplasm] (Gallus gallus)
Association of RAD52 with the RPA complex at resected DNA DSBs (Gallus gallus)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Gallus gallus)
RAD9:HUS1:RAD1 [nucleoplasm] (Gallus gallus)
HUS1 [nucleoplasm] (Gallus gallus)
p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Gallus gallus)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Gallus gallus)
RAD9:HUS1:RAD1 [nucleoplasm] (Gallus gallus)
HUS1 [nucleoplasm] (Gallus gallus)
RAD52 promotes single strand annealing at resected DNA DSBs (Gallus gallus)
RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Gallus gallus)
p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Gallus gallus)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Gallus gallus)
RAD9:HUS1:RAD1 [nucleoplasm] (Gallus gallus)
HUS1 [nucleoplasm] (Gallus gallus)
RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Gallus gallus)
p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Gallus gallus)
ATR:ATRIP:p-RPA:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Gallus gallus)
RAD9:HUS1:RAD1 [nucleoplasm] (Gallus gallus)
HUS1 [nucleoplasm] (Gallus gallus)
Processing of DNA double-strand break ends (Gallus gallus)
ATR activation at DNA DSBs (Gallus gallus)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Gallus gallus)
RAD9:HUS1:RAD1 [nucleoplasm] (Gallus gallus)
HUS1 [nucleoplasm] (Gallus gallus)
RAD9:HUS1:RAD1 [nucleoplasm] (Gallus gallus)
HUS1 [nucleoplasm] (Gallus gallus)
ATR phosphorylates RPA2 (Gallus gallus)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Gallus gallus)
RAD9:HUS1:RAD1 [nucleoplasm] (Gallus gallus)
HUS1 [nucleoplasm] (Gallus gallus)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Gallus gallus)
RAD9:HUS1:RAD1 [nucleoplasm] (Gallus gallus)
HUS1 [nucleoplasm] (Gallus gallus)
External Reference Information
External Reference
UniProt:A0A1D5PTJ5
Gene Names
HUS1
Reference Genes
BioGPS Gene:428471 HUS1
ENSEMBL:ENSGALG00000039589
Monarch:428471 HUS1
NCBI Gene:428471 HUS1
UCSC:A0A1D5PTJ5 HUS1
Reference Transcript
RefSeq:XM_015275913.1 HUS1
RefSeq:XM_426029.5 HUS1
Other Identifiers
428471
GO:0000077
GO:0000723
GO:0000724
GO:0005730
GO:0006281
GO:0006289
GO:0006310
GO:0022414
GO:0030896
GO:0031573
GO:0032200
GO:0033314
GO:0035861
GO:0043226
GO:0044778
GT_A_87_P173158
GgaAffx.23916.1.S1_at
Participates
as a component of
RAD9:HUS1:RAD1 [nucleoplasm] (Gallus gallus)
Inferred From
HUS1 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
XP_015131399.1
,
XP_426029.3
ENSEMBL
ENSGALT00010016400
,
ENSGALP00010009329
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