argininosuccinate <=> fumarate + arginine

Stable Identifier
R-GGA-187617
Type
Reaction [transition]
Species
Gallus gallus
Compartment
cytosol
ReviewStatus
5/5
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argininosuccinate <=> fumarate + arginine
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Cytosolic argininosuccinate lyase (ASL) catalyzes the reversible reaction of argininosuccinate to form fumarate and arginine. The enzyme has been partially purified from kidney tissue (it was undetectable in liver) and biochemically characterized. The ASL gene has not been directly studied but rather has been identified computationally in the ENSEMBL chicken gene set as two open reading frames each capable of encoding a protein similar to human ASL.
Literature References
PubMed ID Title Journal Year
14064979 Enzymes of arginine metabolism in chicks

Ratner, S, Tamir, H

Arch Biochem Biophys 1963
14061730 A study of ornithine, citrulline and arginine synthesis in growing chicks

Ratner, S, Tamir, H

Arch Biochem Biophys 1963
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Catalyst Activity

argininosuccinate lyase activity of ASL-like [cytosol]

Physical Entity
ASL-like [cytosol] (Gallus gallus)
Activity
argininosuccinate lyase activity (GO:0004056)
Authored
Schmidt, C  (2006-09-20)
Reviewed
D'Eustachio, P  (2008-09-10)
Created
Schmidt, C  (2006-09-20)
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