Reactome: A Curated Pathway Database

HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA

Stable Identifier
Gallus gallus
Condensation of acetyl CoA with acetoacetyl CoA to form HMG-CoA
Locations in the PathwayBrowser

This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.

Participant Of
This entity is regulated by:
Title Physical Entity Activity
hydroxymethylglutaryl-CoA synthase activity of Homologues of HMGCS1 [cytosol] Homologues of HMGCS1 [cytosol] hydroxymethylglutaryl-CoA synthase activity (0004421)
Inferred From