Reactome | PTK2 [cytosol]

PTK2 [cytosol]

Stable Identifier

R-GGA-201621

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

cytosol

Synonyms

Q00944

Locations in the PathwayBrowser

Expand all

Immune System (Gallus gallus)

- Innate Immune System (Gallus gallus)
  - Fcgamma receptor (FCGR) dependent phagocytosis (Gallus gallus)
    - Regulation of actin dynamics for phagocytic cup formation (Gallus gallus)
      - Src phosphorylate WASP,N-WASP (Gallus gallus)
        
        Src-kinases [cytosol] (Gallus gallus)
        
        PTK2 [cytosol] (Gallus gallus)

External Reference Information

External Reference

UniProt:Q00944

Reference Genes

ENSEMBL:ENSGALG00000031741

KEGG Gene (Gallus gallus):396416

Reference Transcript

RefSeq:NM_205435.1

Participates

as an input of

as a component of

as a member of

Src-kinases [cytosol] (Gallus gallus)

Other forms of this molecule

phospho-pY-PTK2 [cytosol]

phospho-p-Y194,Y397,Y576,Y577-PTK2 [cytosol]

phospho-p-Y194,Y397-PTK2 [cytosol]

phospho-p-5Y-PTK2 [cytosol]

phospho-p-5Y,S732-PTK2 [cytosol]

phospho-p-6Y,S732-PTK2 [cytosol]

PTK2(773-1052) [cytosol]

PTK2(1-772) [cytosol]

phospho-p-Y397-PTK2 [cytosol]

phospho-p-6Y-PTK2 [cytosol]

Inferred From

PTK2 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_990766.1

IntEnz

2.7.10.2

PRO

Q00944

PDB

6GCR, 2J0K, 4C7T, 4D5H, 4D4S, 3ZDT, 2J0L, 2L6H, 4D4R, 1PV3, 6CB0, 2L6G, 2J0J, 1QVX, 6TY3, 2AL6, 4D58, 2AEH, 2JKQ, 2L6F, 6GCX, 2JKK, 4D4Y, 2JKM, 2JKO, 1KTM, 2J0M, 4CYE, 4D55, 4D4V, 4BRX, 6TY4, 4D5K, 6GCW

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q00944	11	phospho-pY-PTK2 [cytosol] (R-GGA-9632393) phospho-p-Y194,Y397,Y576,Y577-PTK2 [cytosol] (R-GGA-8874613) phospho-p-Y194,Y397-PTK2 [cytosol] (R-GGA-8874600) phospho-p-5Y-PTK2 [cytosol] (R-GGA-5218711) phospho-p-5Y,S732-PTK2 [cytosol] (R-GGA-5229006) phospho-p-6Y,S732-PTK2 [cytosol] (R-GGA-5218694) PTK2(773-1052) [cytosol] (R-GGA-202829) PTK2(1-772) [cytosol] (R-GGA-202827) PTK2 [cytosol] (R-GGA-201621) phospho-p-Y397-PTK2 [cytosol] (R-GGA-354068) phospho-p-6Y-PTK2 [cytosol] (R-GGA-354128)	0.656	3
UniProt:P61157 ACTR3	1	ARP3 [cytosol] (R-BTA-419940)	0.612	5
UniProt:P49024 PAXI			0.609	2
UniProt:P08581 MET	7	p-Y1234,Y1235,Y1356-MET [plasma membrane] (R-HSA-6807014) p-Y1349,Y1356-MET [plasma membrane] (R-HSA-6807032) MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane] (R-HSA-8875181) MonoUb-K,p-Y1003,4Y-MET [plasma membrane] (R-HSA-8875180) p-Y1003,4Y-MET [plasma membrane] (R-HSA-8874689) MET [plasma membrane] (R-HSA-419603) p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane] (R-HSA-6806973)	0.602	5
UniProt:P00523 SRC	9	SRC [cytosol] (R-GGA-9628701) phospho-p-Y419-SRC [cytosol] (R-GGA-8964276) Src [cytosol] (R-GGA-3928468) MyrG-SRC [plasma membrane] (R-GGA-8876922) phospho-p-Y419-SRC [cytosol] (R-GGA-377592) phospho-MyrG,p-Y530-SRC [plasma membrane] (R-GGA-377598) SRC-1 [plasma membrane] (R-GGA-65043) phospho-MyrG-p-Y419-SRC [plasma membrane] (R-GGA-1810408) SRC-2 [cytosol] (R-GGA-191648)	0.589	3

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