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PLCG1 [cytosol]
Stable Identifier
R-GGA-202320
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
PLCG1, A0A8V0ZHR0
Locations in the PathwayBrowser
Expand all
Developmental Biology (Gallus gallus)
Nervous system development (Gallus gallus)
Axon guidance (Gallus gallus)
RET signaling (Gallus gallus)
2x p-5Y-RET:GDNF:GFRA complexes bind PLCgamma1 (Gallus gallus)
2x p-5Y-RET:GDNF:GFRA complexes:PLCG1 [plasma membrane] (Gallus gallus)
PLCG1 [cytosol] (Gallus gallus)
PLCG1 [cytosol] (Gallus gallus)
Hemostasis (Gallus gallus)
Cell surface interactions at the vascular wall (Gallus gallus)
PECAM1 interactions (Gallus gallus)
Interaction of PECAM-1 and PLC gamma1 (Gallus gallus)
PECAM-1:PLC gamma1 complex [plasma membrane] (Gallus gallus)
PLCG1 [cytosol] (Gallus gallus)
PLCG1 [cytosol] (Gallus gallus)
Immune System (Gallus gallus)
Adaptive Immune System (Gallus gallus)
TCR signaling (Gallus gallus)
Generation of second messenger molecules (Gallus gallus)
Phosphorylation of PLC-gamma1 (Gallus gallus)
PLCG1:p-3Y-SLP-76:Gads:LAT [plasma membrane] (Gallus gallus)
PLCG1 [cytosol] (Gallus gallus)
Innate Immune System (Gallus gallus)
DAP12 interactions (Gallus gallus)
DAP12 signaling (Gallus gallus)
Activation of RAC1 by VAV2/3 (Gallus gallus)
p-5Y-LAT:PLCG1:GADS:p-3Y-SLP-76:BTK:p-VAV [plasma membrane] (Gallus gallus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Gallus gallus)
PLC gamma1,2 [cytosol] (Gallus gallus)
PLCG1 [cytosol] (Gallus gallus)
Phosphorylation of PLC-gamma by p-BTK/p-SYK (Gallus gallus)
p-5Y-LAT:GRB2:SOS1:GADS:p-3Y-SLP-76:PLCG:VAV:p-Y223,Y551-BTK [plasma membrane] (Gallus gallus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Gallus gallus)
PLC gamma1,2 [cytosol] (Gallus gallus)
PLCG1 [cytosol] (Gallus gallus)
Recruitment of PLC-gamma to SLP-76 and p-5Y-LAT (Gallus gallus)
PLC gamma1,2 [cytosol] (Gallus gallus)
PLCG1 [cytosol] (Gallus gallus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:SLP76:PLCG [plasma membrane] (Gallus gallus)
PLC gamma1,2 [cytosol] (Gallus gallus)
PLCG1 [cytosol] (Gallus gallus)
Recruitment of VAV and BTK to p-SLP-76 (Gallus gallus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG:VAV:BTK:PIP3 [plasma membrane] (Gallus gallus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Gallus gallus)
PLC gamma1,2 [cytosol] (Gallus gallus)
PLCG1 [cytosol] (Gallus gallus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Gallus gallus)
PLC gamma1,2 [cytosol] (Gallus gallus)
PLCG1 [cytosol] (Gallus gallus)
Fc epsilon receptor (FCERI) signaling (Gallus gallus)
FCERI mediated Ca+2 mobilization (Gallus gallus)
Autophosphorylation of BTK/ITK (Gallus gallus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-2Y-TEC kinases [plasma membrane] (Gallus gallus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Gallus gallus)
PLC gamma1,2 [cytosol] (Gallus gallus)
PLCG1 [cytosol] (Gallus gallus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-TEC kinases:PIP3 [plasma membrane] (Gallus gallus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Gallus gallus)
PLC gamma1,2 [cytosol] (Gallus gallus)
PLCG1 [cytosol] (Gallus gallus)
Phosphorylation of TEC kinases by p-SYK (Gallus gallus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:TEC kinases:PIP3 [plasma membrane] (Gallus gallus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Gallus gallus)
PLC gamma1,2 [cytosol] (Gallus gallus)
PLCG1 [cytosol] (Gallus gallus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-TEC kinases:PIP3 [plasma membrane] (Gallus gallus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Gallus gallus)
PLC gamma1,2 [cytosol] (Gallus gallus)
PLCG1 [cytosol] (Gallus gallus)
FCERI mediated MAPK activation (Gallus gallus)
Activation of RAC1 by VAV (Gallus gallus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV [plasma membrane] (Gallus gallus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Gallus gallus)
PLC gamma1,2 [cytosol] (Gallus gallus)
PLCG1 [cytosol] (Gallus gallus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Gallus gallus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Gallus gallus)
PLC gamma1,2 [cytosol] (Gallus gallus)
PLCG1 [cytosol] (Gallus gallus)
Autophosphorylation of PAK (Gallus gallus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Gallus gallus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Gallus gallus)
PLC gamma1,2 [cytosol] (Gallus gallus)
PLCG1 [cytosol] (Gallus gallus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP:PAK dimer [plasma membrane] (Gallus gallus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Gallus gallus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Gallus gallus)
PLC gamma1,2 [cytosol] (Gallus gallus)
PLCG1 [cytosol] (Gallus gallus)
Phosphorylation and activation of VAV (Gallus gallus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV [plasma membrane] (Gallus gallus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Gallus gallus)
PLC gamma1,2 [cytosol] (Gallus gallus)
PLCG1 [cytosol] (Gallus gallus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV [plasma membrane] (Gallus gallus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Gallus gallus)
PLC gamma1,2 [cytosol] (Gallus gallus)
PLCG1 [cytosol] (Gallus gallus)
Phosphorylation of SLP-76 by p-SYK (Gallus gallus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:SLP76:PLCG [plasma membrane] (Gallus gallus)
PLC gamma1,2 [cytosol] (Gallus gallus)
PLCG1 [cytosol] (Gallus gallus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Gallus gallus)
PLC gamma1,2 [cytosol] (Gallus gallus)
PLCG1 [cytosol] (Gallus gallus)
Recruitment of PAK to the membrane by binding active RAC1 (Gallus gallus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Gallus gallus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Gallus gallus)
PLC gamma1,2 [cytosol] (Gallus gallus)
PLCG1 [cytosol] (Gallus gallus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP:PAK dimer [plasma membrane] (Gallus gallus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Gallus gallus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Gallus gallus)
PLC gamma1,2 [cytosol] (Gallus gallus)
PLCG1 [cytosol] (Gallus gallus)
Recruitment of PLC-gamma to SLP-76 and p-5Y-LAT (Gallus gallus)
PLC gamma1,2 [cytosol] (Gallus gallus)
PLCG1 [cytosol] (Gallus gallus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:SLP76:PLCG [plasma membrane] (Gallus gallus)
PLC gamma1,2 [cytosol] (Gallus gallus)
PLCG1 [cytosol] (Gallus gallus)
Recruitment of VAV to p-SLP-76 (Gallus gallus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Gallus gallus)
PLC gamma1,2 [cytosol] (Gallus gallus)
PLCG1 [cytosol] (Gallus gallus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV [plasma membrane] (Gallus gallus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Gallus gallus)
PLC gamma1,2 [cytosol] (Gallus gallus)
PLCG1 [cytosol] (Gallus gallus)
Fcgamma receptor (FCGR) dependent phagocytosis (Gallus gallus)
Role of phospholipids in phagocytosis (Gallus gallus)
Phosphorylation and activation of PLCG (Gallus gallus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:PLCG [plasma membrane] (Gallus gallus)
PLC gamma1,2 [cytosol] (Gallus gallus)
PLCG1 [cytosol] (Gallus gallus)
Recruitment of PLCgamma to membrane (Gallus gallus)
PLC gamma1,2 [cytosol] (Gallus gallus)
PLCG1 [cytosol] (Gallus gallus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:PLCG [plasma membrane] (Gallus gallus)
PLC gamma1,2 [cytosol] (Gallus gallus)
PLCG1 [cytosol] (Gallus gallus)
Signal Transduction (Gallus gallus)
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by EGFR (Gallus gallus)
EGFR interacts with phospholipase C-gamma (Gallus gallus)
EGFR activates PLC-gamma1 by phosphorylation (Gallus gallus)
EGF-like ligands:p-6Y-EGFR:PLCG1 [plasma membrane] (Gallus gallus)
PLCG1 [cytosol] (Gallus gallus)
Phospholipase C-gamma1 binds to the activated EGF receptor (Gallus gallus)
EGF-like ligands:p-6Y-EGFR:PLCG1 [plasma membrane] (Gallus gallus)
PLCG1 [cytosol] (Gallus gallus)
PLCG1 [cytosol] (Gallus gallus)
Signaling by VEGF (Gallus gallus)
VEGFA-VEGFR2 Pathway (Gallus gallus)
VEGFR2 mediated cell proliferation (Gallus gallus)
SFKs phosphorylate PLCG1 (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:PLCG1 [plasma membrane] (Gallus gallus)
PLCG1 [cytosol] (Gallus gallus)
p-6Y-VEGFR2 binds PLCG1 (Gallus gallus)
PLCG1 [cytosol] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:PLCG1 [plasma membrane] (Gallus gallus)
PLCG1 [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:A0A8V0ZHR0
Gene Names
PLCG1
Reference Genes
BioGPS Gene:419175 PLCG1
ENSEMBL:ENSGALG00010022365.1
Monarch:419175 PLCG1
NCBI Gene:419175 PLCG1
UCSC:A0A8V0ZHR0 PLCG1
Reference Transcript
RefSeq:XM_040687929.2 PLCG1
RefSeq:XM_025142415.3 PLCG1
Other Identifiers
419175
GO:0001726
GO:0004435
GO:0004629
GO:0005168
GO:0005509
GO:0005515
GO:0005737
GO:0005829
GO:0005886
GO:0006629
GO:0007165
GO:0007173
GO:0008081
GO:0008180
GO:0009395
GO:0010634
GO:0016042
GO:0016477
GO:0016787
GO:0019722
GO:0019901
GO:0030027
GO:0032587
GO:0035556
GO:0042995
GO:0043536
GO:0045766
GO:0046488
GO:0046872
GO:0048015
GO:0048870
GO:0051209
GO:0051281
GO:0055085
GO:0071364
GO:1905564
GO:2000353
GT_A_87_P029770
GT_A_87_P133813
Gga.2589.1.S1_at
GgaAffx.25967.2.S1_s_at
Participates
as an input of
2x p-5Y-RET:GDNF:GFRA complexes bind PLCgamma1 (Gallus gallus)
Interaction of PECAM-1 and PLC gamma1 (Gallus gallus)
p-6Y-VEGFR2 binds PLCG1 (Gallus gallus)
Phospholipase C-gamma1 binds to the activated EGF receptor (Gallus gallus)
as a component of
2x p-5Y-RET:GDNF:GFRA complexes:PLCG1 [plasma membrane] (Gallus gallus)
PECAM-1:PLC gamma1 complex [plasma membrane] (Gallus gallus)
PLCG1:p-3Y-SLP-76:Gads:LAT [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:PLCG1 [plasma membrane] (Gallus gallus)
EGF-like ligands:p-6Y-EGFR:PLCG1 [plasma membrane] (Gallus gallus)
as a member of
PLC gamma1,2 [cytosol] (Gallus gallus)
Other forms of this molecule
phospho-PLCG1 [plasma membrane]
phospho-PLCG1 [cytosol]
PLCG1 [plasma membrane]
phospho-PLCG1 [plasma membrane]
Inferred From
PLCG1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_040543863.1
,
XP_024998183.1
ENSEMBL
ENSGALT00010054399
,
ENSGALG00010022365
,
ENSGALP00010032861
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