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SOCS1 [cytosol]
Stable Identifier
R-GGA-204910
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
SOCS1, B6RCQ2
Locations in the PathwayBrowser
Expand all
Immune System (Gallus gallus)
Adaptive Immune System (Gallus gallus)
Class I MHC mediated antigen processing & presentation (Gallus gallus)
Antigen processing: Ubiquitination & Proteasome degradation (Gallus gallus)
Interaction of E3 with substrate and E2-Ub complex (Gallus gallus)
Ag-substrate:E3:E2:Ub [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Gallus gallus)
SOCS-1 and SOCS-3 [cytosol] (Gallus gallus)
SOCS1 [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Gallus gallus)
SOCS-1 and SOCS-3 [cytosol] (Gallus gallus)
SOCS1 [cytosol] (Gallus gallus)
Polyubiquitination of substrate (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Gallus gallus)
SOCS-1 and SOCS-3 [cytosol] (Gallus gallus)
SOCS1 [cytosol] (Gallus gallus)
E3:K48-polyubiquitinated substrate [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Gallus gallus)
SOCS-1 and SOCS-3 [cytosol] (Gallus gallus)
SOCS1 [cytosol] (Gallus gallus)
E3:Ub:substrate [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Gallus gallus)
SOCS-1 and SOCS-3 [cytosol] (Gallus gallus)
SOCS1 [cytosol] (Gallus gallus)
Release of E3 from polyubiquitinated substrate (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Gallus gallus)
SOCS-1 and SOCS-3 [cytosol] (Gallus gallus)
SOCS1 [cytosol] (Gallus gallus)
E3:K48-polyubiquitinated substrate [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Gallus gallus)
SOCS-1 and SOCS-3 [cytosol] (Gallus gallus)
SOCS1 [cytosol] (Gallus gallus)
Transfer of Ub from E2 to substrate and release of E2 (Gallus gallus)
Ag-substrate:E3:E2:Ub [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Gallus gallus)
SOCS-1 and SOCS-3 [cytosol] (Gallus gallus)
SOCS1 [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Gallus gallus)
SOCS-1 and SOCS-3 [cytosol] (Gallus gallus)
SOCS1 [cytosol] (Gallus gallus)
E3:Ub:substrate [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Gallus gallus)
SOCS-1 and SOCS-3 [cytosol] (Gallus gallus)
SOCS1 [cytosol] (Gallus gallus)
Cytokine Signaling in Immune system (Gallus gallus)
Interferon Signaling (Gallus gallus)
Interferon alpha/beta signaling (Gallus gallus)
Activation of JAK kinases (Gallus gallus)
p-TYK2:p-IFNAR1:SOCS-1/SOCS-3:IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Gallus gallus)
p-IFNAR1:p-TYK2:SOCS-1/SOCS-3 [plasma membrane] (Gallus gallus)
SOCS-1 and SOCS-3 [cytosol] (Gallus gallus)
SOCS1 [cytosol] (Gallus gallus)
Interferon gamma signaling (Gallus gallus)
Regulation of IFNG signaling (Gallus gallus)
SOCS-1 and SOCS-3 binds to p-JAK2 (Gallus gallus)
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2:SOCS-1/-3 [plasma membrane] (Gallus gallus)
SOCS-1 and SOCS-3 [cytosol] (Gallus gallus)
SOCS1 [cytosol] (Gallus gallus)
SOCS-1 and SOCS-3 [cytosol] (Gallus gallus)
SOCS1 [cytosol] (Gallus gallus)
Transphosphorylation of JAK1 (Gallus gallus)
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2:SOCS-1/-3 [plasma membrane] (Gallus gallus)
SOCS-1 and SOCS-3 [cytosol] (Gallus gallus)
SOCS1 [cytosol] (Gallus gallus)
Signaling by Interleukins (Gallus gallus)
Interleukin-4 and Interleukin-13 signaling (Gallus gallus)
SOCS5,(SOCS1) bind IL4RA (Gallus gallus)
IL4:IL4R:JAK2:IL13RA:TYK2:SOCS5,(SOCS1) [plasma membrane] (Gallus gallus)
SOCS5,(SOCS1) [cytosol] (Gallus gallus)
SOCS1 [cytosol] (Gallus gallus)
SOCS5,(SOCS1) [cytosol] (Gallus gallus)
SOCS1 [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:B6RCQ2
Gene Names
SOCS1
Reference Genes
BioGPS Gene:416630 SOCS1
ENSEMBL:ENSGALG00000007158
ENSEMBL:ENSGALG00010019269.1 SOCS1
KEGG Gene (Gallus gallus):416630 SOCS1
Monarch:416630 SOCS1
NCBI Gene:416630 SOCS1
Reference Transcript
RefSeq:NM_001137648.1 SOCS1
RefSeq:XM_015294233.1 SOCS1
Other Identifiers
416630
GO:0001817
GO:0001932
GO:0002376
GO:0005159
GO:0005634
GO:0005654
GO:0005942
GO:0006629
GO:0007155
GO:0007259
GO:0009968
GO:0016567
GO:0019210
GO:0019221
GO:0019901
GO:0023052
GO:0030154
GO:0030225
GO:0035556
GO:0036211
GO:0036464
GO:0042509
GO:0042532
GO:0043226
GO:0043372
GO:0043377
GO:0045444
GO:0045591
GO:0046425
GO:0046426
GO:0046627
GO:0046854
GO:0046935
GO:0048856
GO:0071230
GO:0098772
GO:0110165
GT_A_87_P057376
GT_A_87_P151233
Gga.10606.1.S1_at
Participates
as a candidate of
SOCS5,(SOCS1) [cytosol] (Gallus gallus)
as a member of
SOCS-1 and SOCS-3 [cytosol] (Gallus gallus)
Inferred From
SOCS1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_015149719.1
,
NP_001131120.1
OpenTargets
ENSG00000185338
Ensembl
ENSGALG00010019269
,
ENSGALP00010027754
,
ENSGALT00010046591
,
ENSGALP00010027749
,
ENSGALP00010027751
,
ENSGALT00010046593
,
ENSGALT00010046596
PDB
6C7Y
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