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HDAC1 [nucleoplasm]
Stable Identifier
R-GGA-205021
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
nucleoplasm
Synonyms
HDAC1, P56517
Locations in the PathwayBrowser
Expand all
Cell Cycle (Gallus gallus)
Cell Cycle, Mitotic (Gallus gallus)
Mitotic G1 phase and G1/S transition (Gallus gallus)
G0 and Early G1 (Gallus gallus)
Recruitment of HDAC1 by p107 (RBL1) (Gallus gallus)
HDAC1 [nucleoplasm] (Gallus gallus)
HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Gallus gallus)
HDAC1 [nucleoplasm] (Gallus gallus)
Recruitment of HDAC1 by p130 (RBL2) (Gallus gallus)
HDAC1 [nucleoplasm] (Gallus gallus)
HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2 [nucleoplasm] (Gallus gallus)
HDAC1 [nucleoplasm] (Gallus gallus)
Gene expression (Transcription) (Gallus gallus)
RNA Polymerase II Transcription (Gallus gallus)
Generic Transcription Pathway (Gallus gallus)
Notch-HLH transcription pathway (Gallus gallus)
Formation of CSL NCOR corepressor complex (Gallus gallus)
HDAC [nucleoplasm] (Gallus gallus)
HDAC1 [nucleoplasm] (Gallus gallus)
RBPJ:NCOR corepressor complex [nucleoplasm] (Gallus gallus)
HDAC [nucleoplasm] (Gallus gallus)
HDAC1 [nucleoplasm] (Gallus gallus)
Transcriptional regulation by RUNX1 (Gallus gallus)
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function (Gallus gallus)
PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter (Gallus gallus)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:GP1BA gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Gallus gallus)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Gallus gallus)
HDAC1 [nucleoplasm] (Gallus gallus)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:GP1BA gene:H3K4me2-Nucleosome [nucleoplasm] (Gallus gallus)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Gallus gallus)
HDAC1 [nucleoplasm] (Gallus gallus)
PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter (Gallus gallus)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:ITGA2B gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Gallus gallus)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Gallus gallus)
HDAC1 [nucleoplasm] (Gallus gallus)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:ITGA2B gene:H3K4me2-Nucleosome [nucleoplasm] (Gallus gallus)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Gallus gallus)
HDAC1 [nucleoplasm] (Gallus gallus)
PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter (Gallus gallus)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:MIR27A gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Gallus gallus)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Gallus gallus)
HDAC1 [nucleoplasm] (Gallus gallus)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:MIR27A gene:H3K4me2-Nucleosome [nucleoplasm] (Gallus gallus)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Gallus gallus)
HDAC1 [nucleoplasm] (Gallus gallus)
PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter (Gallus gallus)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:THBS1 gene:H3K4me2-Nucleosome [nucleoplasm] (Gallus gallus)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Gallus gallus)
HDAC1 [nucleoplasm] (Gallus gallus)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:THBS1B gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Gallus gallus)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Gallus gallus)
HDAC1 [nucleoplasm] (Gallus gallus)
Hemostasis (Gallus gallus)
Factors involved in megakaryocyte development and platelet production (Gallus gallus)
REST recruits the BHC complex (Gallus gallus)
BHC complex [nucleoplasm] (Gallus gallus)
HDAC1:HDAC2 [nucleoplasm] (Gallus gallus)
HDAC1 [nucleoplasm] (Gallus gallus)
BHC complex:REST:REST DNA binding sites [nucleoplasm] (Gallus gallus)
BHC complex [nucleoplasm] (Gallus gallus)
HDAC1:HDAC2 [nucleoplasm] (Gallus gallus)
HDAC1 [nucleoplasm] (Gallus gallus)
Metabolism of proteins (Gallus gallus)
Post-translational protein modification (Gallus gallus)
SUMOylation (Gallus gallus)
SUMO E3 ligases SUMOylate target proteins (Gallus gallus)
SUMOylation of chromatin organization proteins (Gallus gallus)
SUMOylation of HDAC1 with SUMO1 (Gallus gallus)
HDAC1 [nucleoplasm] (Gallus gallus)
Signal Transduction (Gallus gallus)
Signaling by Nuclear Receptors (Gallus gallus)
ESR-mediated signaling (Gallus gallus)
Estrogen-dependent gene expression (Gallus gallus)
FOXA1 and GATA3 bind to CCND1 promoter (Gallus gallus)
CCND1 gene:H3K4me2 nucleosome:YY1:HDAC1 [nucleoplasm] (Gallus gallus)
HDAC1 [nucleoplasm] (Gallus gallus)
HDAC1 [nucleoplasm] (Gallus gallus)
Signaling by WNT (Gallus gallus)
TCF dependent signaling in response to WNT (Gallus gallus)
Deactivation of the beta-catenin transactivating complex (Gallus gallus)
beta-catenin is replaced by repression complexes at the promoter (Gallus gallus)
TCF/LEF:TLE:HDAC1 [nucleoplasm] (Gallus gallus)
TLE:HDAC1 [nucleoplasm] (Gallus gallus)
HDAC1 [nucleoplasm] (Gallus gallus)
TLE1:HDAC1 [nucleoplasm] (Gallus gallus)
HDAC1 [nucleoplasm] (Gallus gallus)
Formation of the beta-catenin:TCF transactivating complex (Gallus gallus)
Beta-catenin displaces TLE:HDAC1 from TCF/LEF (Gallus gallus)
HDAC1 [nucleoplasm] (Gallus gallus)
TCF/LEF:TLE:HDAC1 [nucleoplasm] (Gallus gallus)
TLE:HDAC1 [nucleoplasm] (Gallus gallus)
HDAC1 [nucleoplasm] (Gallus gallus)
External Reference Information
External Reference
UniProt:P56517
Gene Names
HDAC1
Reference Genes
BioGPS Gene:373961 HDAC1
ENSEMBL:ENSGALG00000003297
KEGG Gene (Gallus gallus):373961 HDAC1
Monarch:373961 HDAC1
NCBI Gene:373961 HDAC1
Reference Transcript
RefSeq:NM_204156.1 HDAC1
Other Identifiers
373961
GO:0000118
GO:0000122
GO:0000228
GO:0000785
GO:0000790
GO:0000792
GO:0000976
GO:0000978
GO:0000979
GO:0001046
GO:0001085
GO:0001103
GO:0002039
GO:0003674
GO:0003677
GO:0003682
GO:0003714
GO:0004407
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005667
GO:0005694
GO:0005737
GO:0005829
GO:0006325
GO:0006346
GO:0006357
GO:0006464
GO:0006476
GO:0007165
GO:0007267
GO:0007492
GO:0007623
GO:0008134
GO:0008150
GO:0008219
GO:0008283
GO:0008284
GO:0009058
GO:0009790
GO:0009913
GO:0010629
GO:0010870
GO:0016575
GO:0016580
GO:0016581
GO:0016787
GO:0016810
GO:0017053
GO:0019213
GO:0019899
GO:0021766
GO:0030154
GO:0030182
GO:0032041
GO:0032922
GO:0032991
GO:0033558
GO:0033613
GO:0034641
GO:0035851
GO:0042475
GO:0042733
GO:0042826
GO:0043025
GO:0043066
GO:0043124
GO:0043226
GO:0043922
GO:0044403
GO:0045892
GO:0045893
GO:0045944
GO:0047485
GO:0048646
GO:0048714
GO:0048856
GO:0051059
GO:0051276
GO:0052548
GO:0060766
GO:0060789
GO:0061029
GO:0061198
GO:0070491
GO:0070888
GO:0070932
GO:0070933
GO:0090090
GO:1990841
GO:2001243
GT_A_87_P003901
GT_A_87_P064526
GT_A_87_P192028
Gga.4985.1.S1_a_at
Gga.4985.1.S2_at
Participant Of
input
Recruitment of HDAC1 by p107 (RBL1)
Recruitment of HDAC1 by p130 (RBL2)
SUMOylation of HDAC1 with SUMO1
hasComponent
CCND1 gene:H3K4me2 nucleosome:YY1:HDAC1 [nucleoplasm]
HDAC1 homodimer [nucleoplasm]
HDAC1:HDAC2 [nucleoplasm]
HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm]
HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2 [nucleoplasm]
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm]
TLE1:HDAC1 [nucleoplasm]
TLE:HDAC1 [nucleoplasm]
output
Beta-catenin displaces TLE:HDAC1 from TCF/LEF
FOXA1 and GATA3 bind to CCND1 promoter
hasMember
HDAC [nucleoplasm]
Other forms of this molecule
HDAC1 [nucleoplasm]
Inferred From
HDAC1 [nucleoplasm] (Homo sapiens)
Cross References
RefSeq
NP_989487.1
OpenTargets
ENSG00000116478
IntEnz
3.5.1.98
Ensembl
ENSGALT00000084635
,
ENSGALG00000003297
,
ENSGALP00000059784
PRO
P56517
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