Hydrolysis of C4b

Stable Identifier
R-GGA-2859050
Type
Reaction [transition]
Species
Gallus gallus
Compartment
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C4b binding to the target surface is regulated by a hydrolysis reaction that irreversibly inactivates C4b. This event is inferred from the annotated human reaction.

Literature References
PubMed ID Title Journal Year
8495193 Covalent binding properties of the human complement protein C4 and hydrolysis rate of the internal thioester upon activation

Sepp, A, Dodds, AW, Anderson, MJ, Campbell, RD, Willis, AC, Law, SK

Protein Sci 1993
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