glyceraldehyde 3-phosphate + NAD+ + phosphate <=> 1,3-bisphosphoglycerate + NADH + H+

Stable Identifier
R-GGA-352956
Type
Reaction
Species
Gallus gallus
Compartment
Synonyms
Dehydrogenation of glyceraldehyde 3-phosphate to form 1,3-bisphosphoglycerate
Locations in the PathwayBrowser
Summation

Cytosolic GAPDH catalyzes the reversible reaction of glyceraldehyde 3-phosphate, NAD+, and phosphate to form 1,3-bisphosphoglycerate and NADH + H+. The active form of the enzyme is a homotetramer (Allison and Kaplan 1964; Dugaiczyk et al. 1983).

Participants
Participant Of
hasEvent
Event Information
Catalyst Activity
Catalyst Activity
Title
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity of GAPDH tetramer [cytosol]
Physical Entity
Activity