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DNA Damage Reversal
Stable Identifier
R-GGA-353239
Type
Pathway
Species
Gallus gallus
Compartment
nucleoplasm
ReviewStatus
5/5
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DNA replication and repair (Gallus gallus)
DNA repair (Gallus gallus)
DNA Damage Reversal (Gallus gallus)
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The direct reversal of DNA damage is obviously the most straightforward mode of DNA repair. A single-step repair reaction is considerably simpler compared to the multi-step biochemical pathways required in other DNA repair pathways (e.g., excision repair, NHEJ, recombination repair). Except for the alkyltransferase mode of repair that is energetically expensive, a reverse mode of DNA repair is in general also kinetically advantageous as it utilizes single gene product for rapid correction of the damage.
Participants
Events
MGMT mediated DNA Damage Reversal
(Gallus gallus)
Reversal of Alkylation Damage By DNA Dioxygenases
(Gallus gallus)
Participates
as an event of
DNA repair (Gallus gallus)
Event Information
Go Biological Process
DNA dealkylation involved in DNA repair (0006307)
Authored
Saxena, A (2008-07-07)
Reviewed
Borowiec, JA (2009-04-24)
Created
Saxena, A (2008-06-12)
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