Interaction between two DNA-PK:DNA complexes at opposing ends of DNA DSB

Stable Identifier
R-GGA-353265
Type
Reaction [binding]
Species
Gallus gallus
Compartment
nucleoplasm
ReviewStatus
5/5
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Interaction between two DNA-PK:DNA complexes at opposing ends of DNA DSB
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The DNA-PK-Ku complex translocates away from the DSB. Subsequently, two DNA-PK-DNA complexes, one on either side of the break, interact to bring the DNA ends together in synaptic complex. This reaction is inferred from its human counterpart.
Participants
Input
Output
Participates
as an event of
Inferred From
Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis (Homo sapiens)
Authored
Saxena, A  (2008-07-07)
Reviewed
Borowiec, JA  (2009-04-24)
Created
Saxena, A  (2008-06-12)
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