Reactome: A Curated Pathway Database

oxaloacetate + NADH + H+ <=> malate + NAD+

Stable Identifier
R-GGA-372422
Type
Reaction
Species
Gallus gallus
Compartment
Locations in the PathwayBrowser
Summation

Oxaloacetate is reversibly reduced by NADH + H+ to form malate and NAD+. No chicken enzyme capable of catalyzing this reaction has been identified, although an open reading frame capable of encoding a protein closely similar to authentic human mitochondrial malate dehydrogenase (MDH2) has been identified computationally in the ENSEMBL chicken gene set. This reaction is inferred from its human counterpart.

Participants
Participant Of
This entity is regulated by:
Title Physical Entity Activity
L-malate dehydrogenase activity of MDH2 [mitochondrial matrix] MDH2 [mitochondrial matrix] L-malate dehydrogenase activity (0030060)
Inferred From