2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix]

Stable Identifier
R-GGA-372742
Type
Reaction [transition]
Species
Gallus gallus
Compartment
Synonyms
Exchange of cytosolic 2-oxoadipate for mitochondrial 2-oxoglutarate
General
SVG |   | PPTX  | SBGN
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SLC25A21, the mitochondrial 2-oxodicarboxylate carrier, mediates the exchange of 2-oxoadipate and 2-oxoglutarate across the inner mitochondrial membrane. No chicken transport protein capable of mediating this reaction has been identified, although an open reading frame capable of encoding a protein closely similar to authentic human SLC25A21 has been identified computationally in the ENSEMBL chicken gene set. This reaction is inferred from its human counterpart.

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
alpha-ketoglutarate transmembrane transporter activity of SLC25A21 [mitochondrial inner membrane]
Physical Entity
Activity
Inferred From
Authored
Created