succinylCoA + GDP + Pi <=> succinate + CoASH + GTP

Stable Identifier
R-GGA-372980
Type
Reaction [transition]
Species
Gallus gallus
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Mitochondrial succinyl-CoA synthetase catalyzes the reversible reaction of succinylCoA, GDP, and orthophosphate to form succinate, CoASH, and GTP. The enzyme is a heterodimer consisting of an alpha chain and a beta chain that determines whether the reaction involves adenine nucleotides or guanine nucleotides (as here). The biochemical properties of the chicken enzyme have been studied in detail (Hamilton and Ottaway 1981) but the genes encoding its component proteins have not been cloned. The molecular properties of these proteins are inferred from those of their pigeon homologues (Johnson et al. 1998).
Literature References
Participants
Participates
Catalyst Activity

succinate-CoA ligase (GDP-forming) activity of succinyl-CoA synthetase dimer, GDP-forming [mitochondrial matrix]

Authored
Created
Cite Us!