isocitrate + NAD+ => 2-oxoglutarate (alpha-ketoglutarate) + CO2 + NADH + H+

Stable Identifier
R-GGA-373024
Type
Reaction [transition]
Species
Gallus gallus
Compartment
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Mitochondrial isocitrate dehydrogenase (IDH3-like) catalyzes the reaction of isocitrate and NAD+ to form 2-oxoglutarate (alpha-ketoglutarate), CO2, and NADH + H+. No chicken enzyme capable of catalyzing this reaction has been identified, although an open reading frame capable of encoding a protein closely similar to authentic human mitochondrial isocitrate dehydrogenase (IDH3) has been identified computationally in the ENSEMBL chicken gene set. This reaction is inferred from its human counterpart.

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
isocitrate dehydrogenase (NAD+) activity of IDH3-like [mitochondrial matrix]
Physical Entity
Activity
Inferred From
Authored
Created