2-oxoglutarate (alpha-ketoglutarate) + CoASH + NAD+ => succinylCoA + CO2 + NADH + H+

Stable Identifier
R-GGA-373042
Type
Reaction [transition]
Species
Gallus gallus
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Mitochondrial 2-oxoglutarate (alpha-ketoglutarate) dehydrogenase complex catalyzes the reaction of 2-oxoglutarate, CoASH, and NAD+ to form succinylCoA, CO2, and NADH + H+. No chicken enzyme complex capable of catalyzing this reaction has been identified, although open reading frames capable of encoding proteins closely similar to each of the three authentic human 2-oxoglutarate dehydrogenase E1, E2, and E3 subunits have been identified computationally in the ENSEMBL chicken gene set. This reaction is inferred from its human counterpart.
Participants
Participates
Catalyst Activity

oxoglutarate dehydrogenase (NAD+) activity of 2-oxoglutarate dehydrogenase complex [mitochondrial matrix]

Inferred From
Authored
Created
Cite Us!