malate + NAD+ <=> oxaloacetate + NADH + H+

Stable Identifier
R-GGA-373047
Type
Reaction
Species
Gallus gallus
Compartment
Locations in the PathwayBrowser
Summation

MDH2 (mitochondrial malate dehydrogenase) catalyzes the reversible reaction of malate and NAD+ to form oxaloacetate and NADH + H+. No chicken enzyme capable of catalyzing this reaction has been identified, although an open reading frame capable of encoding a protein closely similar to authentic human mitochondrial malate dehydrogenase (MDH2) has been identified computationally in the ENSEMBL chicken gene set. This reaction is inferred from its human counterpart.

Participants
Participant Of
Event Information
Catalyst Activity
Catalyst Activity
Title
L-malate dehydrogenase activity of MDH2 [mitochondrial matrix]
Physical Entity
Activity
Inferred From