Reactome: A Curated Pathway Database

fumarate + H2O <=> malate

Stable Identifier
R-GGA-373145
Type
Reaction
Species
Gallus gallus
Compartment
Locations in the PathwayBrowser
Summation

Mitochondrial FH (fumarate hydratase) catalyzes the reversible reaction of fumarate and H2O to form malate. No chicken enzyme capable of catalyzing this reaction has been identified, although an open reading frame capable of encoding a protein closely similar to authentic human mitochondrial FH has been identified computationally in the ENSEMBL chicken gene set. This reaction is inferred from its human counterpart.

Participants
Participant Of
This entity is regulated by:
Title Physical Entity Activity
fumarate hydratase activity of FH [mitochondrial matrix] FH [mitochondrial matrix] fumarate hydratase activity (0004333)
Inferred From