succinate + FAD <=> fumarate + FADH2

Stable Identifier
R-GGA-373147
Type
Reaction [transition]
Species
Gallus gallus
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

The SDH (succinate dehydrogenase) complex, embedded in the inner mitochondrial membrane, catalyzes the reversible oxidation of succinate to fumarate, coupled to the reduction of SDH-associated FAD to FADH2. No chicken enzyme capable of catalyzing this reaction has been characterized, although open reading frames capable of encoding three of the four proteins predicted from characterization of authentic human mitochondrial succinate dehydrogenase has been identified computationally in the ENSEMBL chicken gene set or in large-scale screens of cDNA clones. This reaction is inferred from its human counterpart.

Participants
Participant Of
Event Information
Catalyst Activity
Catalyst Activity
Title
succinate dehydrogenase (ubiquinone) activity of SDH complex [mitochondrial inner membrane]
Physical Entity
Activity
Inferred From
Authored
Created