2 protoporphyrinogen IX + 3 O2 => 2 protoporphyrin IX + 6 H2O

Stable Identifier
R-GGA-421452
Type
Reaction [transition]
Species
Gallus gallus
Compartment
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PPOX dimer in the mitochondrial intermembrane space catalyzes the reaction of two molecules of protoporphyrinogen IX and three of oxygen to form two molecules of protoporphyrin IX and sx of water. While the process of heme biosynthesis, including this reaction, is believed to be well conserved among vertebrates, no chicken gene capable of encoding a PPOX homologue has yet been discovered, and this reaction and all of the properties of chicken PPOX enzyme are inferred from those of their better-studied human counterparts.

Participants
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
oxygen-dependent protoporphyrinogen oxidase activity of PPOX dimer [mitochondrial intermembrane space]
Physical Entity
Activity
Inferred From
Authored
Created
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