coproporphyrinogen III + 2 O2 => protoporphyrinogen IX + 2 H2O2 + 2 CO2

Stable Identifier
R-GGA-421478
Type
Reaction [transition]
Species
Gallus gallus
Compartment
ReviewStatus
5/5
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CPOX (coproporphyrinogen III oxidase) localized in the mitochondrial intermembrane space catalyzes the reaction of coproporphyrinogen III with two molecules of O2 to form protoporphyrinogen IX, rwo molecules of H2O2, and two molecules of CO2. Chicken CPOX is known only as the inferred product of a gene discovered by analysis of the chicken genomic DNA sequence. Its subcellular location, dimerization to form an active enzyme, and catalytic activity are inferred from the properties of its better-studied human counterpart.
Participants
Participates
Catalyst Activity

coproporphyrinogen oxidase activity of CPOX dimer [mitochondrial intermembrane space]

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Authored
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