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ARHGEF7 [cytosol]
Stable Identifier
R-GGA-430346
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
ARHGEF7, A0A3Q2TZR1
Locations in the PathwayBrowser
Expand all
Developmental Biology (Gallus gallus)
Nervous system development (Gallus gallus)
Axon guidance (Gallus gallus)
EPH-Ephrin signaling (Gallus gallus)
Ephrin signaling (Gallus gallus)
GIT1 binds bPIX (Gallus gallus)
ARHGEF7 [cytosol] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Gallus gallus)
ARHGEF7 [cytosol] (Gallus gallus)
PAK binds RAC and bPIX (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Gallus gallus)
ARHGEF7 [cytosol] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Gallus gallus)
ARHGEF7 [cytosol] (Gallus gallus)
PAKs autophosphorylate (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Gallus gallus)
ARHGEF7 [cytosol] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:p-PAK1,3 [plasma membrane] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Gallus gallus)
ARHGEF7 [cytosol] (Gallus gallus)
PAKs phosphorylate MLC (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:p-PAK1,3 [plasma membrane] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Gallus gallus)
ARHGEF7 [cytosol] (Gallus gallus)
bPIX exchanges GTP for GDP on RAC, activating it (Gallus gallus)
ARHGEF7 [cytosol] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Gallus gallus)
ARHGEF7 [cytosol] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Gallus gallus)
ARHGEF7 [cytosol] (Gallus gallus)
Signal Transduction (Gallus gallus)
Death Receptor Signaling (Gallus gallus)
p75 NTR receptor-mediated signalling (Gallus gallus)
Cell death signalling via NRAGE, NRIF and NADE (Gallus gallus)
NRAGE signals death through JNK (Gallus gallus)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Gallus gallus)
GEFs [cytosol] (Gallus gallus)
ARHGEF7 [cytosol] (Gallus gallus)
Signaling by GPCR (Gallus gallus)
GPCR downstream signalling (Gallus gallus)
G alpha (12/13) signalling events (Gallus gallus)
GEFs activate RhoA,B,C (Gallus gallus)
GEFs [cytosol] (Gallus gallus)
ARHGEF7 [cytosol] (Gallus gallus)
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by EGFR (Gallus gallus)
EGFR downregulation (Gallus gallus)
Beta-Pix:CDC42:GTP binds CBL in EGF:p-6Y-EGFR:CBL:CIN85 (Gallus gallus)
Beta-Pix:CDC42:GTP [cytosol] (Gallus gallus)
ARHGEF7 [cytosol] (Gallus gallus)
EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 [plasma membrane] (Gallus gallus)
Beta-Pix:CDC42:GTP [cytosol] (Gallus gallus)
ARHGEF7 [cytosol] (Gallus gallus)
CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix (Gallus gallus)
EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP [plasma membrane] (Gallus gallus)
Beta-Pix:CDC42:GTP [cytosol] (Gallus gallus)
ARHGEF7 [cytosol] (Gallus gallus)
Ub-Beta-Pix:CDC42:GTP [cytosol] (Gallus gallus)
ARHGEF7 [cytosol] (Gallus gallus)
CDC42:GTP binds CBL:Beta-Pix (Gallus gallus)
Beta-Pix:CDC42:GTP [cytosol] (Gallus gallus)
ARHGEF7 [cytosol] (Gallus gallus)
CBL:Beta-Pix:CDC42:GTP [cytosol] (Gallus gallus)
Beta-Pix:CDC42:GTP [cytosol] (Gallus gallus)
ARHGEF7 [cytosol] (Gallus gallus)
CIN85 dissociates from EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 (Gallus gallus)
EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP [plasma membrane] (Gallus gallus)
Beta-Pix:CDC42:GTP [cytosol] (Gallus gallus)
ARHGEF7 [cytosol] (Gallus gallus)
EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 [plasma membrane] (Gallus gallus)
Beta-Pix:CDC42:GTP [cytosol] (Gallus gallus)
ARHGEF7 [cytosol] (Gallus gallus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Gallus gallus)
Signaling by Rho GTPases (Gallus gallus)
RHO GTPase cycle (Gallus gallus)
RAC1 GTPase cycle (Gallus gallus)
RAC1 GEFs activate RAC1 (Gallus gallus)
RAC1 GEFs [cytosol] (Gallus gallus)
ARHGEF7 [cytosol] (Gallus gallus)
RHOA GTPase cycle (Gallus gallus)
RHOA GEFs activate RHOA (Gallus gallus)
RHOA GEFs [cytosol] (Gallus gallus)
ARHGEF7 [cytosol] (Gallus gallus)
RHOQ GTPase cycle (Gallus gallus)
RHOQ binds effectors at the plasma membrane (Gallus gallus)
RHOQ effectors [cytosol] (Gallus gallus)
ARHGEF7 [cytosol] (Gallus gallus)
RHOQ:GTP:RHOQ effectors [plasma membrane] (Gallus gallus)
RHOQ effectors [cytosol] (Gallus gallus)
ARHGEF7 [cytosol] (Gallus gallus)
RHOU GTPase cycle (Gallus gallus)
RHOU binds effectors at the plasma membrane (Gallus gallus)
RHOU effectors [cytosol] (Gallus gallus)
ARHGEF7 [cytosol] (Gallus gallus)
RHOU:GTP:RHOU effectors [plasma membrane] (Gallus gallus)
RHOU effectors [cytosol] (Gallus gallus)
ARHGEF7 [cytosol] (Gallus gallus)
RHOV GTPase cycle (Gallus gallus)
RHOV binds effectors at the plasma membrane (Gallus gallus)
RHOV effectors [cytosol] (Gallus gallus)
ARHGEF7 [cytosol] (Gallus gallus)
RHOV:GTP:RHOV effectors [plasma membrane] (Gallus gallus)
RHOV effectors [cytosol] (Gallus gallus)
ARHGEF7 [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:A0A3Q2TZR1
Gene Names
ARHGEF7
Reference Genes
BioGPS Gene:418761 ARHGEF7
ENSEMBL:ENSGALG00000031009
ENSEMBL:ENSGALG00010013080.1 ARHGEF7
KEGG Gene (Gallus gallus):418761 ARHGEF7
Monarch:418761 ARHGEF7
NCBI Gene:418761 ARHGEF7
Reference Transcript
RefSeq:XM_003640531.2 ARHGEF7
Other Identifiers
418761
GO:0000322
GO:0002244
GO:0005085
GO:0005515
GO:0005737
GO:0005773
GO:0005829
GO:0005886
GO:0019901
GO:0023052
GO:0030027
GO:0030032
GO:0030154
GO:0035556
GO:0043226
GO:0048856
GO:0060124
GO:0098772
GO:0098794
GT_A_87_P110513
GgaAffx.10787.1.S1_at
Participates
as a candidate of
RHOA GEFs [cytosol] (Gallus gallus)
RHOV effectors [cytosol] (Gallus gallus)
RHOQ effectors [cytosol] (Gallus gallus)
CDC42 effectors [cytosol] (Gallus gallus)
RAC1 GEFs [cytosol] (Gallus gallus)
RHOJ effectors [cytosol] (Gallus gallus)
RHOU effectors [cytosol] (Gallus gallus)
as an input of
GIT1 binds bPIX (Gallus gallus)
as a component of
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Gallus gallus)
Ub-Beta-Pix:CDC42:GTP [cytosol] (Gallus gallus)
Beta-Pix:CDC42:GTP [cytosol] (Gallus gallus)
as a member of
GEFs [cytosol] (Gallus gallus)
Inferred From
ARHGEF7 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_003640579.1
OpenTargets
ENSG00000102606
Ensembl
ENSGALG00010013080
,
ENSGALT00010031379
,
ENSGALP00010018307
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