viral dsRNA: TLR3: TICAM1 recruits TRAF6

Stable Identifier
R-GGA-433808
Type
Reaction [binding]
Species
Gallus gallus
Related Species
Infectious bronchitis virus
Compartment
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TRAF6 is recruited to the N-terminal domain of TICAM1 and this event is followed by auto polyubiquitination and oligomerization of TRAF6.

Chicken TRAF6 protein, confirmed by transcript evidence, shows 76% amino acid sequence identity with human TRAF6.

Literature References
PubMed ID Title Journal Year
16306937 Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6

Hsu, LC, Raz, E, Häcker, G, Karin, M, Kamps, MP, Mann, M, Kratchmarova, I, Redecke, V, Blagoev, B, Häcker, H, Wagner, H, Wang, GG

Nature 2006
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