Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
ERK2(MAPK1) [cytosol]
Stable Identifier
R-GGA-433942
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Innate Immune System (Gallus gallus)
Toll-like receptors (TLR) cascades (Gallus gallus)
TLR15 cascade (Gallus gallus)
MyD88 cascade initiated on plasma membrane (Gallus gallus)
NFkB and MAPK activation mediated by TRAF6 (Gallus gallus)
MAPK activation in TLR cascade (Gallus gallus)
ERK activation (Gallus gallus)
activated MEK2 binds ERK2 (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
phospho MEK2 : ERK2 [cytosol] (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
activated MEK2 phosphorylates ERK2 (Gallus gallus)
phospho MEK2 : ERK2 [cytosol] (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
TLR2 subfamily cascade (Gallus gallus)
MyD88:TIRAP-dependent cascade initiated on plasma membrane (Gallus gallus)
NFkB and MAPK activation mediated by TRAF6 (Gallus gallus)
MAPK activation in TLR cascade (Gallus gallus)
ERK activation (Gallus gallus)
activated MEK2 binds ERK2 (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
phospho MEK2 : ERK2 [cytosol] (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
activated MEK2 phosphorylates ERK2 (Gallus gallus)
phospho MEK2 : ERK2 [cytosol] (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
TLR21 cascade (Gallus gallus)
MyD88-dependent cascade initiated on endosome membrane (Gallus gallus)
NFkB and MAPK activation mediated by TRAF6 upon TLR7 or TLR21 stimulation (Gallus gallus)
MAPK activation in TLR cascade (Gallus gallus)
ERK activation (Gallus gallus)
activated MEK2 binds ERK2 (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
phospho MEK2 : ERK2 [cytosol] (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
activated MEK2 phosphorylates ERK2 (Gallus gallus)
phospho MEK2 : ERK2 [cytosol] (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
TLR3 cascade (Gallus gallus)
TRAF6 mediated induction of proinflammatory cytokines (Gallus gallus)
MAPK activation in TLR cascade (Gallus gallus)
ERK activation (Gallus gallus)
activated MEK2 binds ERK2 (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
phospho MEK2 : ERK2 [cytosol] (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
activated MEK2 phosphorylates ERK2 (Gallus gallus)
phospho MEK2 : ERK2 [cytosol] (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
TLR4 cascade (Gallus gallus)
MyD88:TIRAP-dependent cascade initiated on plasma membrane (Gallus gallus)
NFkB and MAPK activation mediated by TRAF6 (Gallus gallus)
MAPK activation in TLR cascade (Gallus gallus)
ERK activation (Gallus gallus)
activated MEK2 binds ERK2 (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
phospho MEK2 : ERK2 [cytosol] (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
activated MEK2 phosphorylates ERK2 (Gallus gallus)
phospho MEK2 : ERK2 [cytosol] (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
TLR5 cascade (Gallus gallus)
MyD88 cascade initiated on plasma membrane (Gallus gallus)
NFkB and MAPK activation mediated by TRAF6 (Gallus gallus)
MAPK activation in TLR cascade (Gallus gallus)
ERK activation (Gallus gallus)
activated MEK2 binds ERK2 (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
phospho MEK2 : ERK2 [cytosol] (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
activated MEK2 phosphorylates ERK2 (Gallus gallus)
phospho MEK2 : ERK2 [cytosol] (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
TLR7 cascade (Gallus gallus)
MyD88-dependent cascade initiated on endosome membrane (Gallus gallus)
NFkB and MAPK activation mediated by TRAF6 upon TLR7 or TLR21 stimulation (Gallus gallus)
MAPK activation in TLR cascade (Gallus gallus)
ERK activation (Gallus gallus)
activated MEK2 binds ERK2 (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
phospho MEK2 : ERK2 [cytosol] (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
activated MEK2 phosphorylates ERK2 (Gallus gallus)
phospho MEK2 : ERK2 [cytosol] (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:Q8UWG6 Extracellular signal-regulated kinase 2
Gene Names
MAPK1
Reference Genes
BioGPS Gene:373953 MAPK1
KEGG Gene (Gallus gallus):373953 MAPK1
Monarch:373953 MAPK1
NCBI Gene:373953 MAPK1
Reference Transcript
RefSeq:NM_204150.1 MAPK1
RefSeq:XM_015275131.1 MAPK1
Participant Of
input
activated MEK2 binds ERK2
hasComponent
phospho MEK2 : ERK2 [cytosol]
Other forms of this molecule
phospho-ERK2 [nucleoplasm]
phospho-ERK2 [cytosol]
Cross References
RefSeq
XP_015130617.1
,
NP_989481.1
OpenTargets
ENSG00000100030
© 2021
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text