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NFkB1_p50 [cytosol]
Stable Identifier
R-GGA-433962
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Innate Immune System (Gallus gallus)
RLR (RIG-like receptor) mediated induction of IFN alpha/beta (Gallus gallus)
TRAF6 mediated NF-kB activation (Gallus gallus)
activated IKKs phosphorylates IkB alpha causing the NFkB complex to dissociate from the phospho-IkB (Gallus gallus)
IkB alpha : NFkB complex [cytosol] (Gallus gallus)
NFkB1_p50 [cytosol] (Gallus gallus)
NFkB complex(p50/p65) [cytosol] (Gallus gallus)
NFkB1_p50 [cytosol] (Gallus gallus)
Toll-like receptors (TLR) cascades (Gallus gallus)
TLR15 cascade (Gallus gallus)
MyD88 cascade initiated on plasma membrane (Gallus gallus)
NFkB and MAPK activation mediated by TRAF6 (Gallus gallus)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Gallus gallus)
Released NFkB complex migrates to the nucleus and turns on transcription (Gallus gallus)
NFkB complex(p50/p65) [cytosol] (Gallus gallus)
NFkB1_p50 [cytosol] (Gallus gallus)
activated IKKs phosphorylates IkB alpha causing the NFkB complex to dissociate from the phospho-IkB (Gallus gallus)
IkB alpha : NFkB complex [cytosol] (Gallus gallus)
NFkB1_p50 [cytosol] (Gallus gallus)
NFkB complex(p50/p65) [cytosol] (Gallus gallus)
NFkB1_p50 [cytosol] (Gallus gallus)
TLR2 subfamily cascade (Gallus gallus)
MyD88:TIRAP-dependent cascade initiated on plasma membrane (Gallus gallus)
NFkB and MAPK activation mediated by TRAF6 (Gallus gallus)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Gallus gallus)
Released NFkB complex migrates to the nucleus and turns on transcription (Gallus gallus)
NFkB complex(p50/p65) [cytosol] (Gallus gallus)
NFkB1_p50 [cytosol] (Gallus gallus)
activated IKKs phosphorylates IkB alpha causing the NFkB complex to dissociate from the phospho-IkB (Gallus gallus)
IkB alpha : NFkB complex [cytosol] (Gallus gallus)
NFkB1_p50 [cytosol] (Gallus gallus)
NFkB complex(p50/p65) [cytosol] (Gallus gallus)
NFkB1_p50 [cytosol] (Gallus gallus)
TLR21 cascade (Gallus gallus)
MyD88-dependent cascade initiated on endosome membrane (Gallus gallus)
NFkB and MAPK activation mediated by TRAF6 upon TLR7 or TLR21 stimulation (Gallus gallus)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Gallus gallus)
Released NFkB complex migrates to the nucleus and turns on transcription (Gallus gallus)
NFkB complex(p50/p65) [cytosol] (Gallus gallus)
NFkB1_p50 [cytosol] (Gallus gallus)
activated IKKs phosphorylates IkB alpha causing the NFkB complex to dissociate from the phospho-IkB (Gallus gallus)
IkB alpha : NFkB complex [cytosol] (Gallus gallus)
NFkB1_p50 [cytosol] (Gallus gallus)
NFkB complex(p50/p65) [cytosol] (Gallus gallus)
NFkB1_p50 [cytosol] (Gallus gallus)
TLR3 cascade (Gallus gallus)
NFkB activation mediated by RIP1 complexed with activated TLR3 (Gallus gallus)
Released NFkB complex migrates to the nucleus and turns on transcription (Gallus gallus)
NFkB complex(p50/p65) [cytosol] (Gallus gallus)
NFkB1_p50 [cytosol] (Gallus gallus)
activated IKKs phosphorylates IkB alpha causing the NFkB complex to dissociate from the phospho-IkB (Gallus gallus)
IkB alpha : NFkB complex [cytosol] (Gallus gallus)
NFkB1_p50 [cytosol] (Gallus gallus)
NFkB complex(p50/p65) [cytosol] (Gallus gallus)
NFkB1_p50 [cytosol] (Gallus gallus)
TRAF6 mediated induction of proinflammatory cytokines (Gallus gallus)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Gallus gallus)
Released NFkB complex migrates to the nucleus and turns on transcription (Gallus gallus)
NFkB complex(p50/p65) [cytosol] (Gallus gallus)
NFkB1_p50 [cytosol] (Gallus gallus)
activated IKKs phosphorylates IkB alpha causing the NFkB complex to dissociate from the phospho-IkB (Gallus gallus)
IkB alpha : NFkB complex [cytosol] (Gallus gallus)
NFkB1_p50 [cytosol] (Gallus gallus)
NFkB complex(p50/p65) [cytosol] (Gallus gallus)
NFkB1_p50 [cytosol] (Gallus gallus)
TLR4 cascade (Gallus gallus)
MyD88:TIRAP-dependent cascade initiated on plasma membrane (Gallus gallus)
NFkB and MAPK activation mediated by TRAF6 (Gallus gallus)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Gallus gallus)
Released NFkB complex migrates to the nucleus and turns on transcription (Gallus gallus)
NFkB complex(p50/p65) [cytosol] (Gallus gallus)
NFkB1_p50 [cytosol] (Gallus gallus)
activated IKKs phosphorylates IkB alpha causing the NFkB complex to dissociate from the phospho-IkB (Gallus gallus)
IkB alpha : NFkB complex [cytosol] (Gallus gallus)
NFkB1_p50 [cytosol] (Gallus gallus)
NFkB complex(p50/p65) [cytosol] (Gallus gallus)
NFkB1_p50 [cytosol] (Gallus gallus)
TLR5 cascade (Gallus gallus)
MyD88 cascade initiated on plasma membrane (Gallus gallus)
NFkB and MAPK activation mediated by TRAF6 (Gallus gallus)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Gallus gallus)
Released NFkB complex migrates to the nucleus and turns on transcription (Gallus gallus)
NFkB complex(p50/p65) [cytosol] (Gallus gallus)
NFkB1_p50 [cytosol] (Gallus gallus)
activated IKKs phosphorylates IkB alpha causing the NFkB complex to dissociate from the phospho-IkB (Gallus gallus)
IkB alpha : NFkB complex [cytosol] (Gallus gallus)
NFkB1_p50 [cytosol] (Gallus gallus)
NFkB complex(p50/p65) [cytosol] (Gallus gallus)
NFkB1_p50 [cytosol] (Gallus gallus)
TLR7 cascade (Gallus gallus)
MyD88-dependent cascade initiated on endosome membrane (Gallus gallus)
NFkB and MAPK activation mediated by TRAF6 upon TLR7 or TLR21 stimulation (Gallus gallus)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Gallus gallus)
Released NFkB complex migrates to the nucleus and turns on transcription (Gallus gallus)
NFkB complex(p50/p65) [cytosol] (Gallus gallus)
NFkB1_p50 [cytosol] (Gallus gallus)
activated IKKs phosphorylates IkB alpha causing the NFkB complex to dissociate from the phospho-IkB (Gallus gallus)
IkB alpha : NFkB complex [cytosol] (Gallus gallus)
NFkB1_p50 [cytosol] (Gallus gallus)
NFkB complex(p50/p65) [cytosol] (Gallus gallus)
NFkB1_p50 [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:Q04861 NFKB1
Gene Names
NFKB1
Chain
chain:1-983, chain:1-
Reference Genes
BioGPS Gene:396033 NFKB1
KEGG Gene (Gallus gallus):396033 NFKB1
Monarch:396033 NFKB1
NCBI Gene:396033 NFKB1
Reference Transcript
RefSeq:XM_015285415.1 NFKB1
RefSeq:NM_205134.1 NFKB1
Participates
as a component of
NFkB complex(p50/p65) [cytosol] (Gallus gallus)
IkB alpha : NFkB complex [cytosol] (Gallus gallus)
Other forms of this molecule
NFKB1 [specific granule lumen]
NFKB1 [extracellular region]
NFKB1 [secretory granule lumen]
NFkB1_p50 [nucleoplasm]
NFKB1 [cytosol]
NFKB1 [nucleoplasm]
NFKB1 [cytosol]
phospho-NFKB1 [cytosol]
phospho-NFKB1 [cytosol]
Cross References
RefSeq
NP_990465.1
,
XP_015140901.1
OpenTargets
ENSG00000109320
PRO
Q04861
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