Dimerization of Phospho-IRF3

Stable Identifier
R-GGA-434027
Type
Reaction
Species
Gallus gallus
Compartment
Locations in the PathwayBrowser
Summation

Phosphorylation results in IRF-3 dimerization and removal of an autoinhibitory structure to allow interaction with the coactivators CBP/p300.

Literature References
PubMed ID Title Journal Year
14555995 X-ray crystal structure of IRF-3 and its functional implications Nat Struct Biol 2003
Participants
Participant Of
Inferred From