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C111-AcM-UBE2M-G76-NEDD8 [cytosol]
Stable Identifier
R-GGA-4419895
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
A0A1D5PRI6
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Gallus gallus)
Post-translational protein modification (Gallus gallus)
Neddylation (Gallus gallus)
AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex (Gallus gallus)
NEDD8-AcM-UBE2M:CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Gallus gallus)
NEDD8-AcM-UBE2M [cytosol] (Gallus gallus)
C111-AcM-UBE2M-G76-NEDD8 [cytosol] (Gallus gallus)
AcM-UBE2M transfers NEDD8 to CRL2 E3 ubiquitin ligase complex (Gallus gallus)
NEDD8-AcM-UBE2M:CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Gallus gallus)
NEDD8-AcM-UBE2M [cytosol] (Gallus gallus)
C111-AcM-UBE2M-G76-NEDD8 [cytosol] (Gallus gallus)
AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex (Gallus gallus)
NEDD8-AcM-UBE2M:CRL3 E3 ubiquitin ligase :DCUN1D1,2,4,5 [cytosol] (Gallus gallus)
NEDD8-AcM-UBE2M [cytosol] (Gallus gallus)
C111-AcM-UBE2M-G76-NEDD8 [cytosol] (Gallus gallus)
NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex (Gallus gallus)
NEDD8-AcM-UBE2M [cytosol] (Gallus gallus)
C111-AcM-UBE2M-G76-NEDD8 [cytosol] (Gallus gallus)
NEDD8-AcM-UBE2M:CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Gallus gallus)
NEDD8-AcM-UBE2M [cytosol] (Gallus gallus)
C111-AcM-UBE2M-G76-NEDD8 [cytosol] (Gallus gallus)
NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex (Gallus gallus)
NEDD8-AcM-UBE2M [cytosol] (Gallus gallus)
C111-AcM-UBE2M-G76-NEDD8 [cytosol] (Gallus gallus)
NEDD8-AcM-UBE2M:CRL3 E3 ubiquitin ligase :DCUN1D1,2,4,5 [cytosol] (Gallus gallus)
NEDD8-AcM-UBE2M [cytosol] (Gallus gallus)
C111-AcM-UBE2M-G76-NEDD8 [cytosol] (Gallus gallus)
Transfer of NEDD8 to AcM-UBE2M (Gallus gallus)
NEDD8-AcM-UBE2M [cytosol] (Gallus gallus)
C111-AcM-UBE2M-G76-NEDD8 [cytosol] (Gallus gallus)
Signal Transduction (Gallus gallus)
Signaling by TGFB family members (Gallus gallus)
Signaling by TGF-beta Receptor Complex (Gallus gallus)
TGF-beta receptor signaling activates SMADs (Gallus gallus)
CBL neddylates TGFBR2 (Gallus gallus)
NEDD8-AcM-UBE2M [cytosol] (Gallus gallus)
C111-AcM-UBE2M-G76-NEDD8 [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:A0A1D5PRI6
Reference Genes
ENSEMBL:ENSGALG00000036955
Participates
as a component of
NEDD8-AcM-UBE2M [cytosol] (Gallus gallus)
Other forms of this molecule
C111-AcM-UBE2M-G76-NEDD8 [nucleoplasm]
NEDD8 [nucleoplasm]
C116-AcM-UBE2F-G76-NEDD8 [cytosol]
NEDD8(77-88) [cytosol]
NEDD8(1-88) [cytosol]
C237-UBA3-G76-NEDD8 [cytosol]
NEDD8 [cytosol]
Inferred From
C111-AcM-UBE2M-G76-NEDD8 [cytosol]
(Homo sapiens)
Modified Residues
Name
Inter-chain Crosslink via S-(glycyl)-L-cysteine (Cys-Gly) at 76 and 111 (in Homo sapiens)
Coordinate
76
PsiMod Name
S-(glycyl)-L-cysteine (Cys-Gly)
PsiMod Definition
A protein modification that effectively crosslinks an L-cysteine residue and a glycine residue by a thioester bond to form S-glycyl-L-cysteine.
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